基于ICP－MS截尾数据与支持向量机优化模型鉴别蜂蜜植物源

该文开展了一种电感耦合等离子体质谱(ICP－MS)截尾数据和支持向量机(SVM)分类模型识别蜂蜜植物源的研究.实验选取荆条蜜、洋槐蜜、葵花蜜、油菜蜜4种不同植物源的蜂蜜共97例,经微波消解等预处理后,采用ICP-MS分别测得蜂蜜样品中16种金属元素的含量,并研究13种具有显著性差异的金属元素,以含截尾数据和不含截尾数据...     

黄芩-栀子配伍治疗糖尿病肾病大鼠的尿液代谢组学研究

采用基于超高效液相色谱与串联四极杆飞行时间质谱仪(Ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry,UHPLC-Q-TOF MS)联用的代谢组学方法,通过分析大鼠尿液内源性代谢物的变化,研究黄芩-栀子药对治疗糖尿病肾病的作用机制。利用高脂高糖饲料喂养并腹腔注射链脲佐菌素(STZ)建立糖尿病大鼠模型。给药12周后,采用UHPLC-Q-TOF MS对正常对照组、模型组、黄芩-栀子药对治疗组的尿液样品进行代谢轮廓分析。利用正交偏最小二乘判别分析(Orthogonal partial least squares discriminant analysis,OPLS-DA)对实验数据进行分析,挑选出对各组分分离贡献较大(VIP>1,p<0.05)的化合物在Human Metabolome Database(HMDB)等数据库进行质谱信息匹配,共鉴定出糖尿病肾病潜在生物标记物31个,给药后回调生物标记物16个。研究结果表明,黄芩-栀子...     

光交联法合成水凝胶的研究

合成了一种新型光敏性功能单体N -肉桂酰氧甲基丙烯酰胺 (CMMAM)及其与丙烯酸 (AA)的共聚物(CMMAM -AA) ,通过光交联法进一步合成水凝胶 .测定了CMMAM和CMMAM -AA聚合物的红外光谱 ,测定了水凝胶的DSC并对它的溶胀性能进行了初步研究     

卫星激光通信系统设计分析

结合卫星激光通信实验演示系统的研制，对卫星激光通信系统的总体设计以及系统的结构设计、激光器的选择、捕获、对准、跟踪（Acquisition,Pointing and Tracking-APT)技术，背景光抑制与光学滤波器设计，光行程差与超前对准补偿等关键技术进行了深入的分析和讨论，得出了有关结论。     

超细蒙脱石制备及其作为氟尿嘧啶药物控释载体的实验研究

采用超细技术制备出超细蒙脱石，使蒙脱石比表面积大幅提高，吸附能力显著增强；并且利用超细蒙脱石的无毒性、高比表面积、高吸附性等性质，将其作为抗癌药物氟尿嘧啶的控释载体，研究了超细蒙脱石对氟尿嘧啶的吸附及体外释放性能；体外释放实验表明，超细蒙脱石具有良好的控释性能；使超细蒙脱石有望成为一种新型药物控释载体。     

Synthesis and Crystal Structure of N,N′-4-aminomethyl-pyromellitic diimide

The title compound N,N′-4-aminomethyl-pyromellitic diimide (4-pmpmd) crystallizes in monoclinic, space group P21/c with a = 4.785(1), b = 6.200(1), c = 29.907(2) (A), β =93.583(11)°, V= 885.5(2) (A)3, Dc = 1.494 g/cm3, Z = 2, C22H14N4O4, Mr = 398.37,μ(MoKα) = 0.106mm-1 and F(000) = 412, and its structure was refined to R = 0.0469 and wR = 0.1017 for 1194observed reflections (Fo ＞ 4σ(Fo)). The X-ray diffraction shows the existence of the staggered multi-dimensional supramolecular network based on the Z-mode conformation of the title compound.     

从FeSe0.5Te0.5的V～I曲线论磁通动力学的诸模型（英文）

高温超导体的发现动摇了支配磁通动力学二十几年的Kim-Anderson模型.于是人们提出了新的涡旋玻璃态模型,集体钉扎模型和U～j对数关系模型来描述高温超导体的磁通动力学.其中,涡旋玻璃态模型已被人们广泛接受.Fe基超导体发现后,人们它行为十分类似于高温超导体.我们实验上仔细研究了FeSe0.5Te0.5单晶的V～I关系曲线,发现上述诸模型均不能很好的解释我们的实验结果,而张的反跳模型恰能很好的拟合实验结果.本文讨论了诸模型对高温超导体磁通动力学描述的适用性并给出合理的解释.     

Cooling of Akmal-Pandharipande-Ravenhall neutron stars with a rotochemical heating source

Employing phenomenological density-dependent critical temperatures of strong singlet-state proton pairing and of moderate triplet-state neutron pairing, we investigate the effects of rotochemical heating on the thermal evolution of superfluid neutron stars whose cores consist of npe matter with the Akmal-Pandharipande-Ravenhall equation of state. Since the star is not quite in the weak interaction equilibrium state during spin-down, the departure from the chemical equilibrium leads to the rotochemical heating in a rotating NS which will increase the stellar＇s temperature. Our calculations show that the rotochemical heating delays the cooling of superfluid neutron stars considerably and makes the previous classification of NS cooling ambiguous. What＇s more, our model is currently consistent with all the observational data, and in particular some middle-aged and cold NSs （PRS J0205＋6449 in 3C 58, PRS J1357-6429, RX J007.0＋7303 in CTA 1, Vela） can be better explained when taking into account rotochemical heating.     

Cooling of Akmal-Pandharipande-Ravenhall neutron stars with a rotochemical heating source

Employing phenomenological density-dependent critical temperatures of strong singlet-state proton pairing and of moderate triplet-state neutron pairing, we investigate the effects of rotochemical heating on the thermal evolution of superfluid neutron stars whose cores consist of npe matter with the Akmal-Pandharipande-Ravenhall equation of state. Since the star is not quite in the weak interaction equilibrium state during spin-down, the departure from the chemical equilibrium leads to the rotochemical heating in a rotating NS which will increase the stellar's temperature. Our calculations show that the rotochemical heating delays the cooling of superfluid neutron stars considerably and makes the previous classification of NS cooling ambiguous. What's more, our model is currently consistent with all the observational data, and in particular some middle-aged and cold NSs (PRS J0205+6449 in 3C 58, PRS J1357-6429, RX J007.0+7303 in CTA 1, Vela) can be better explained when taking into account rotochemical heating.     

超声乳化溶剂扩散法制备阿奇霉素超细粉体

采用超声乳化溶剂扩散法制备了阿奇霉素超细粉体，讨论了溶剂、温度、阿奇霉素浓度以及稳定剂种类和用量等条件对微粉粒径及形貌的影响．实验结果表明，在实验选定的最佳实验条件下(结晶温度0～5℃，阿奇霉素浓度0．03mol／L，1％聚乙二醇(PEG)、乙醇为溶剂)，可制备出平均粒径为500nm的均匀分散阿奇霉素超细粉体。