增压O_2/CO_2气氛下煤燃烧特性实验研究

增压O2/CO2燃烧是一种可高效分离回收CO2的新兴燃烧技术,其燃烧机理与常压空气、常压O2/CO2燃烧存在较大差异。在加压热重分析仪上研究了增压条件下总压、氧浓度、气氛及粒径等反应参数对美国烟煤和淮北无烟煤燃烧特性的影响,确定了煤的着火温度,并对其进行燃烧动力学分析。结果表明,增压O2/CO2气氛下,随着压力或氧浓度的增加,DTG曲线向低温区移动,煤样整体燃烧速率加快。压力提升、氧浓度增加及煤粉细化均可改善O2/CO2气氛下煤样的着火特性。常压O2/CO2气氛下煤粉燃烧基本属于一级反应;增压O2/CO2气氛下,低温区属于0.5级反应,而高温区属于1.5级反应。     

“海水提镁”项目式教学设计与实践*

依托广西北海市丰富的海洋资源,创设了“在北海能否建提镁厂”的驱动性总任务,师生合议将任务规划为3个大问题和6个子任务。学生采用信息收集、分类、比较、推理、实验、系统分析等认知策略,最终以ppt的形式进行成果汇报,通过组间评价、核心问题讨论、决策性问题辩论等方式逐步落实项目目标。     

微生物发酵诱导多孔材料: 制备方法和应用

微生物发酵作为一种新的制备多孔材料的方式, 将微生物发酵工程与发泡工程有机结合起来, 克服了传统制备方法需要特殊设备、 操作复杂、 后处理繁琐、 化学药品污染和成本昂贵等缺点, 受到了广泛关注.本文基于微生物发酵多孔材料的研究, 围绕多孔材料的定义和多孔水凝胶的分类及制备方式进行总结.针对微生物发酵诱导制备多孔材料的制备方法, 综合评述了该方法在染料吸附、 海水蒸发脱盐、 电磁屏蔽以及制备新型功能性生物材料等方面的应用.最后, 对微生物诱导制备多孔材料的未来发展进行了展望.     

有机化学课程思政教学实践*

结合课程思政教学情况的现状,梳理了有机化学课程思政开展的过程实践,解释了有机化学课程思政教学目标的创设思路,列举了有机化学课程思政元素案例,阐述了有机化学课程思政教学的4个措施,并进行了有机化学课程思政教学效果的初步评价。     

Revealing the Cell Entry Dynamic Mechanism of Single Rabies Virus Particle

The rabies virus is a neurotropic virus that causes fatal diseases in humans and animals. Although studying the interactions between a single rabies virus and the cell membrane is necessary for understanding the pathogenesis, the internalization dynamic mechanism of single rabies virus in living cells remains largely elusive. Here, we utilized a novel force tracing technique based on atomic force microscopy(AFM) to record the process of single viral entry into host cell. We revealed that the force of the rabies virus internalization distributed at (65±25) pN, and the time was identified by two peaks with spacings of (237.2±59.1) and (790.3±134.4) ms with the corresponding speed of 0.12 and 0.04 μm/s, respectively. Our results provide insight into the effects of viral shape during the endocytosis process. This report will be meaningful for understanding the dynamic mechanism of rabies virus early infection.     

Metal-Organic Frameworks-derived Indium Clusters/Carbon Nanocomposites for Efficient CO2 Electroreduction

Electrochemical reduction of carbon dioxide into value-added products is a promising way to recycle the greenhouse gas, thus solving the crisis of global warming. Pressing challenges remain in regulating the catalytic selectivity. In this work, we demonstrated a metal-organic frameworks-assisted approach to synthesizing In species loaded on the surface of N doped carbon matrix. By controlling the particle sizes, the catalytic selectivity can be easily altered. The obtained In_c/NC possesses the outstanding capability for converting CO₂ into CO. And 80.09% Faraday efficiency (FE) of CO can be achieved at 0.8 V vs. RHE. While the In₂O₃/C exhibits different catalytic behaviors, the main product is formic acid and the FE is more than 50% at 0.8 V vs. RHE. The selectivity reversal can be attributed to the strong interactions between In clusters and N atoms of carbon supports, which efficiently inhibits the formation of the by-product, formic acid. Our research has paved a new way to modulate catalytic selectivity by manipulating the fine structures of the catalysts.     

Fabrication and Excellent Antibacterial Activity of Well-defined CuO/Graphdiyne Nanostructure

Copper oxide(CuO),due to its low cost,good chemical and physical stability,has recently been given special attention as a potential candidate for antibacterial agents.However,developing novel CuO nanocomposites with improved antibacterial property and unraveling the interface promotion mechanism has been a fundamental challenge for decades.Herein,well-defined CuO/graphdiyne(CuO/GDY)nanostructures with uniformly anchored CuO nanoparticles(ca.4.5 nm)have been fabricated.The CuO/GDY nanostructure exhibited superior E.coli inactivation efficiency,which is nearly 19 times and 7.9 times higher than the bare GDY and commercial CuO,respectively.The improved E.coli inactivation performance was mainly due to the increased reactive O2-species generated by the activation of molecular O2 over CuO/GDY surface.These findings demonstrate the efficient antibacterial activity of well-defined CuO/GDY nanostructures and provide insights on the development of efficient GDY-based antibacterial materials.     

互联网B/S架构交互式软件在核心概念教学中的应用*——以国际IB课程中“电解质”内容为例

基于核心概念教学的思路,国际IB课程互联网B/S架构交互式软件能够使学生围绕“电解质”核心概念,通过自行操作软件获得多个从微观到宏观、定性与定量相结合、可视化的实验证据,有利于学生深度理解概念与概念之间的逻辑和发展关系,促进学科知识系统框架的形成。     

马面鲀鱼皮复制及润湿性研究

以具有防污功能的马面鲀皮为生物复制模板,采用铸膜方法对其微观形貌进行了大面积复制,并对复制表面的润湿性进行了分析研究。研究结果表明,复制的PDMS样品表面产生了与生物样品一致性较好的绒毛结构。该结构大大增加了表面的疏水性,将使海洋生物附着的难度大幅度增大,从而改善表面的污损释放性能。     

藤黄酸诱导肺癌细胞H1975凋亡的机制研究

目的 研究藤黄酸（GA）诱导人肺癌细胞H1975凋亡的分子机制,探讨氧自由基（ROS）和JNK信号通路在GA杀伤 肺癌细胞中的作用。方法 以人肺癌细胞H1975为研究对象,MTT法测定GA抑制细胞增殖的作用,Annexin V/PI 双染法测定细胞凋亡率,DCFH-DA 法测定ROS 含量,JC-1探针染色分析线粒体膜电位（MMP）,Western blot检测JNK 信号通路的激活和线粒体凋亡途径相关蛋白表达的变化。结果 GA 呈剂量依赖性抑制H1975细胞的增殖,各实验组细胞存活率与空白对照组比较,均有统计学差异（P＜0.05 或0.01）。1、2.5 和5滋mol/L GA 作用24h 后,细胞凋亡率分别为25.2%、51.8%和75.1%,剪切型凋亡相关蛋白cleaved caspase-9、cleaved caspase-3 和cleaved PARP 的表达随GA 浓度增高而显著增加,与空白对照组比较,均有统计学差异（P＜0.05或0.01）。GA 作用2h 后H1975细胞ROS 含量显著升高,磷酸化JNK（p-JNK）表达上调（P＜0.05或0.01）。GA 作用16h后各实验组细胞MMP 均明显降低（均P＜0.05）。GA 作用24h后实验组细胞线粒体凋亡途径相关蛋白Bax、Bak、Bik表达增加,而抗凋亡蛋白Bcl-2表达与空白对照组相比明显下降（P＜0.05 或0.01）。结论 GA 具有诱导H1975 细胞凋亡的作用,其可能机制是上调细胞内ROS含量,激活JNK 信号通路,进而引起MMP 降低和线粒体凋亡途径激活。