The 3-D FEL pulse propagation equation: An analytical treatment in the low-gain and small-signal regime

Summary In this paper we show that the transverse mode evolution of a FEL operating with short pulses can be treated, in the small-signal and low-gain regime, using a relatively simple mathematical technique leading to a potentially fast numerical algorithm. We also point out that analytical solutions can be obtained for the cases where the slippage length is small compared to the longitudinal bunch length.     

Paramagnetic defects in BaTiO3 and their role in light-induced charge transport — Optical studies

On the basis of a previous identification of paramagnetic defects in nominally undoped as grown BaTiO₃ single crystals, we have investigated the changes of the concentrations of these centers and their optical absorptions under illumination with light of varying wavelengths. The most pronounced charge transfers occur by hole ionization of Fe⁴⁺ and — to a lesser extent — of Cr⁵⁺ and Cr⁴⁺. At low temperatures the created holes are trapped in the form of O^–-ions next to Al³⁺ or unknown acceptor defects. Corresponding Fe⁴⁺ and O^– absorptions have been identified.     

Characterization of carbide phases in high speed tool steels

A study is reported on carbides electrolytically extracted from two different types of high speed tool steels as quenched and after tempering. According to X-ray diffraction analysis and EDS microanalysis, Mössbauer spectra show the presence of MC and M₆C in every analysed sample. Only a few substitutional Fe atoms should be present in MC and they give a minor contribution to the Mössbauer spectrum. A model for evaluating the Mössbauer spectrum of M₆C is proposed which is based on the symmetry of lattice sites occupied by Fe atoms and partially substituted by other metallic atoms. The proposed model also allows to get information on the amount of this substitution.     

The electron current to a Langmuir probe in a flowing high-pressureplasma

The electron current to a Langmuir probe in a moving high-pressure plasma has been measured and analyzed. The plasma is an atmospheric-pressure propane flame, and the probe's speed relative to the plasma was varied from 10 ms^-1 to 30 ms^-1. The current is linearly dependent on the speed and appears to be comprised of two components-one driven by diffusion and the other by convection. A model is devised which can be used to measure the electron density. By comparing the density computed from this model to that measured from the ion current, it has been possible to measure the electron mobility in the flame gases. The value obtained by the authors is in good agreement with theoretical calculations found in the literature     

Validation of a solid-phase extraction high-performance liquid chromatographic assay for doxazosin.

The determination of doxazosin by high-performance liquid chromatography with fluorescence detection is described. Propanolol was used as the internal standard. Plasma samples were treated with methanol to precipitate the proteins. Doxazosin was isolated with C18 reversed-phase extraction columns. The determination limit is 1 ng/ml of plasma, while the extraction columns can be reused frequently. The method is applied to clinical trial samples.     

Analysis of platelet-activating factor by gas chromatography-mass spectrometry: low-energy electron impact of the corresponding 3-acetyl-2-tert.-butyldimethylsilyl derivative.

A method for the analysis of platelet-activating factor in platelets employing gas chromatography and selected-ion monitoring mass spectrometry with low-energy electron impact and stable isotope dilution was developed. The procedure involved Bligh and Dyer extraction of the sample followed by thin-layer chromatographic purification. Platelet-activating factor is successively hydrolysed to the corresponding 2-acetyl-1-O-alkylglycerol by digestion with phospholipase C, and the product is allowed to isomerize to the more thermodynamically stable 3-acetyl-1-O-alkylglycerol before column purification and derivatization of the free OH with tert.-butyldimethylchlorosaline-imidazole. This reagent is of common use in platelet-activating factor derivatization, but is made to react with 2-acetyl instead of 3-acetyl isomer. The advantages of using the latter for the final derivatization are discussed and this method is compared with others currently available for gas chromatographic-mass spectrometric analysis of platelet-activating factor.     

Direct quantitative digital autoradiography-thin-layer chromatography of 3 alpha,3 beta- and 5 alpha-reduced and 17 beta-dehydrogenated androgens derived from testosterone metabolism.

A digital autoradiographic-thin-layer chromatographic method involving simple steps is described for thorough separation of eight major androgens (testosterone, androstenedione, dihydrotestosterone, androsterone, epiandrosterone, androstanedione, 3 alpha-androstanediol and 3 beta-androstanediol) derived from testosterone metabolism. Their direct quantification is performed by radioscanning, which avoids tedious plate-scraping and liquid scintillation counting. Satisfactory accuracy is obtained by both external standardization of plates by calibrated amounts of radiolabelled standard steroids and internal standardization of bioassays by radiolabelled squalane. Coefficients of variation are below 8.5% in the range 100-500 dpm. Some analytical criteria related to chromatographic conditions and quantification parameters depending on position-sensitive proportional counter are discussed.     

Magnetic resonance imaging (MRI) and pathophysiology of the rat kidney in streptozotocin-induced diabetes.

Proton magnetic resonance imaging was performed on rats before induction of diabetes with streptozotocin (STZ) and at 2 and 12 days postinduction. Images revealed an increase in maximal longitudinal and axial dimensions of the kidneys at 2 days and a further increase at 12 days. Similarly, an increase in the size of the remaining kidney was seen in a rat which underwent uninephrectomy as a positive control. Two major differences were observed between the kidney undergoing compensatory hypertrophy and those developing diabetic nephropathy: (i) Expansion of the renal vasculature was seen only in images of the diabetic rat; (ii) A loss in conspicuity of the normal corticomedullary junction was seen in the T2-weighted images of the diabetic rat but not in the uninephrectomized rat. Histologic examination revealed that the medulla increased to a size greater than the cortex during diabetic nephropathy whereas the medullary volume was less than that of the cortex during compensatory hypertrophy. In vitro T1 relaxation times in cortex, outer medulla and inner medulla of kidneys from control rats were measured and compared with the same respective regions in diabetic rats. When these values were correlated with tissue water content, a linear increase in relaxation rate versus percent water content from cortex to inner medulla was found in the control kidneys, but this correlation was absent in diabetic nephropathy. These studies demonstrate that MRI is an effective noninvasive tool for studying the course of renal hypertrophy and hydration changes in the development of renal disease in STZ-induced diabetes in the rat.     

Electron Energy Distribution Functions in CO2 Laser Mixture: The Effects of Second Kind Collisions from Metastable Electronic States

Electron energy distribution functions (eedf) in CO₂ laser discharge (He—CO₂—N₂—CO mixture) have been calculated by solving the Boltzmann equation in the presence of given concentrations of excited (vibrational and electronic) states. The results show a well structured eedf as a result of second kind collisions coming from metastable electronic states of N₂ and He as well as a strong dependence of rate coefficients for CO₂ dissociation and for the ionization of the different species.