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61.
Rostami Mojtaba Aghajanzadeh Mozhgan Zamani Mostafa Manjili Hamidreza Kheiri Danafar Hossein 《Research on Chemical Intermediates》2018,44(3):1889-1904
Research on Chemical Intermediates - In this study, a kind of magnetic Fe3O4@mTiO2-GO (where m was shorted mesoporous) hybrids with core–shell nano-structure for controlled dual targeted drug... 相似文献
62.
Nasser Sally Salama Ismail Mostafa Samia M. Elgawish Mohamed Saleh 《平面色谱法杂志一现代薄层色谱法》2018,31(6):469-476
JPC – Journal of Planar Chromatography – Modern TLC - The discovery of potent antidiabetic drugs is of necessity owing to the rapid prevalence of diabetes worldwide. The investigation... 相似文献
63.
Hashemzadeh Alireza Amini Mostafa M. Najafi Ezzatollah Khavasi Hamid Reza 《Research on Chemical Intermediates》2017,43(10):5741-5753
Research on Chemical Intermediates - To systematically examine the effects of the length and number of aromatic rings in carboxylic acid ligands on the structure and properties of lead(II)... 相似文献
64.
Leila Torkian Mostafa M. Amini Tayebeh Gorji Omid Sadeghi 《Arabian Journal of Chemistry》2019,12(7):1315-1321
In this study, multiwalled carbon nanotube (MWCNT) was modified by the pyridine group using a silane agent and characterized by infrared spectroscopy (IR), thermal analysis (TG/DTA), and elemental analysis (CHN) and scanning electron microscopy (SEM). The application of this sorbent was investigated in determination of lead ions in aqueous samples, using flame atomic absorption spectrometry (FAAS). Through this study, different parameters such as pH and sample flow rate on adsorption process and eluent concentration, volume and flow rate were optimized. The limit of detection (LOD), the relative standard deviation and the recovery of the method were 2 ng mL?1, 1.3% and 99.7%, respectively. Two standard reference materials (NIST 1571 and NIST 1572) were used to verify accuracy of this method. Finally, the sorbent was successfully applied for extraction and determination of low levels of Pb(II) ions in aqueous samples. 相似文献
65.
Dr. Safaa M. Kishk Dr. Kirsty J. McLean Dr. Sakshi Sood Darren Smith Jack W.D. Evans Prof. Mohamed A. Helal Prof. Mohamed S. Gomaa Prof. Ismail Salama Prof. Samia M. Mostafa Dr. Luiz Pedro S. de Carvalho Colin W. Levy Prof. Andrew W. Munro Dr. Claire Simons 《ChemistryOpen》2019,8(7):995-1011
The emergence of untreatable drug-resistant strains of Mycobacterium tuberculosis is a major public health problem worldwide, and the identification of new efficient treatments is urgently needed. Mycobacterium tuberculosis cytochrome P450 CYP121A1 is a promising drug target for the treatment of tuberculosis owing to its essential role in mycobacterial growth. Using a rational approach, which includes molecular modelling studies, three series of azole pyrazole derivatives were designed through two synthetic pathways. The synthesized compounds were biologically evaluated for their inhibitory activity towards M. tuberculosis and their protein binding affinity (KD). Series 3 biarylpyrazole imidazole derivatives were the most effective with the isobutyl ( 10 f ) and tert-butyl ( 10 g ) compounds displaying optimal activity (MIC 1.562 μg/mL, KD 0.22 μM ( 10 f ) and 4.81 μM ( 10 g )). The spectroscopic data showed that all the synthesised compounds produced a type II red shift of the heme Soret band indicating either direct binding to heme iron or (where less extensive Soret shifts are observed) putative indirect binding via an interstitial water molecule. Evaluation of biological and physicochemical properties identified the following as requirements for activity: LogP >4, H-bond acceptors/H-bond donors 4/0, number of rotatable bonds 5–6, molecular volume >340 Å3, topological polar surface area <40 Å2. 相似文献
66.
67.
The spiro-compound 3′H-spiro[indole-3,2′-[1,3]benzothiazole-2(1H)-one (IBTH2) was synthesized and its structure was determined using spectroscopic techniques (FTIR, 1H NMR and mass) and X-ray crystallography. This ligand possesses different centers for coordination. Reactions of [M(CO)6], M = Cr, Mo or W with IBTH2 in THF under reduced pressure were studied. For chromium a complex with molecular formula [Cr(ITP)2] was isolated; where ITP is the opened form of the ligand which occurred through Cspiro–S bond, while [Mo(CO)5(IBTH2)] and [W(CO)5(IBTH2)] were isolated from the reaction of IBTH2 with molybdenum and tungsten carbonyls, respectively. All complexes were characterized by elemental analysis, IR, mass and 1H NMR spectroscopy. The biological activity of the ligand and its complexes were studied and compared with the parent compound isatin. 相似文献
68.
Mohsen M. Mostafa Rafaat M. El-Shazly Tawfik H. Rakha Mohamed H. Abdel-Rahman 《Transition Metal Chemistry》2002,27(2):237-237
Other Index
Forthcoming articles 相似文献69.
70.
MostafaADIMY MostafaLAKLACH KhalilEZZINBI 《数学学报(英文版)》2004,20(5):933-942
In this work, we are concerned with a general class of abstract semilinear autonomous functional differential equations with a non-dense domain on a Banach space. Our objective is to study, using the Crandall-Liggett approach, the solutions as a semigroup of non-linear operators. 相似文献