In this paper we introduce the multiscale cell boundary element method (MsCBE method). The method is obtained by applying the oversampling technique of the MsFEM by Hou and Wu [T.Y. Hou, X.H. Wu, A multiscale finite element method for elliptic problems in composite materials and porous media, J. Comput. Phys. 134 (1997) 169–189] to the newly developed numerical method, the cell boundary element(CBE) method by the author and his colleagues. The advantage of the MsCBE method is that it preserves flux exactly on arbitrary subdomain without needing the dual mesh. A complete H1 convergence analysis and numerical examples confirming our analysis are presented. 相似文献
The aim of this study is to characterize urban spaces, which combine landscape, acoustics, and lighting, and to investigate people's perceptions of urban soundscapes through quantitative and qualitative analyses. A general questionnaire survey and soundwalk were performed to investigate soundscape perception in urban spaces. Non-auditory factors (visual image, day lighting, and olfactory perceptions), as well as acoustic comfort, were selected as the main contexts that affect soundscape perception, and context preferences and overall impressions were evaluated using an 11-point numerical scale. For qualitative analysis, a semantic differential test was performed in the form of a social survey, and subjects were also asked to describe their impressions during a soundwalk. The results showed that urban soundscapes can be characterized by soundmarks, and soundscape perceptions are dominated by acoustic comfort, visual images, and day lighting, whereas reverberance in urban spaces does not yield consistent preference judgments. It is posited that the subjective evaluation of reverberance can be replaced by physical measurements. The categories extracted from the qualitative analysis revealed that spatial impressions such as openness and density emerged as some of the contexts of soundscape perception. 相似文献
Reactive oxygen species (ROS) has been implicated as an inducer of NF-kappaB activity in numbers of cell types where exposure of cells to ROS such as H(2)O(2) leads to NF-kappaB activation. In contrast, exposure to oxidative stress in certain cell types induced reduction of tumor necrosis factor (TNF)- induced NF-kappaB activation. And various thiol-modifying agents including gold compounds and cyclopentenone prostaglandins inhibit NF-kappaB activation by blocking IkappaB kinase (IKK). To understand such conflicting effect of oxidative stress on NF- kappakB activation, HeLa cells were incubated with H(2)O(2) or diamide and TNF-induced expression of NF-kappaB reporter gene was measured. NF-kappaB activation was significantly blocked by these oxidizing agents, and the inhibition was accompanied with reduced nuclear NF-kappaB and inappropriate cytosolic IkappaB degradation. H(2)O(2) and diamide also inhibited IKK activation in HeLa and RAW 264.7 cells stimulated with TNF and lipopolysaccharide, respectively, and directly blocked IKK activity in vitro. In cells treated with H(2)O(2) alone, nuclear NF-kappaB was induced after 2 h without detectable degradation of cytosolic IkappaBalphaa or activation of IKK. Our results suggest that ROS has a dual effect on NF-kappaB activation in the same HeLa cells: it inhibits acute IKK-mediated NF-kappakB activation induced by inflammatory signals, while longer-term exposure to ROS induces NF-kappaB activity through an IKK-independent pathway. 相似文献
We review and extend the composite fermion theory for semiconductor quantum dots in high magnetic fields. The mean-field model
of composite fermions is unsatisfactory for the qualitative physics at high angular momenta.
Extensive numerical calculations demonstrate that the microscopic CF theory,
which incorporates interactions between composite fermions, provides an excellent qualitative and quantitative account
of the quantum dot ground state down to the largest angular momenta studied,
and allows systematic improvements by inclusion of mixing between composite
fermion Landau levels (called Λ levels). 相似文献
Russian Journal of Physical Chemistry A - In the present work, the effect of temperature and moisture has been studied on nano-porous polycarbonate membranes of size 15, 50, and 80 nm, respectively... 相似文献
Apoptosis is one of the fundamental phenomena behind successful radiation and chemotherapy treatments. Non-invasive imaging of apoptosis can offer an early diagnosis of disease and the true efficiency of an ongoing treatment procedure. The present study describes an attempt to develop 99mTc-labeled 2-methyl-2-pentylmalonic acid ([99mTc] 8) as a new SPECT based apoptosis imaging agent. An optimized chemical and radiosynthesis procedure provided desired product [99mTc] 8 with high radiochemical yield (84%, n = 3) and radiochemical purity (>99%) as determined by radio HPLC. Biodistribution data indicated that the radiotracer has a rapid clearance from blood and other background tissues. High testes accumulation confirmed the ability of the radiotracer to detect testicular apoptosis in mice.
Optical Review - A dual-path handheld system is proposed for cornea and retina imaging using spectral domain optical coherence tomography. The handheld sample arm is designed to acquire two images... 相似文献
A three-dimensional (3D) particle image velocimetry measurement technique capable of simultaneously monitoring 3D fluid flows and the structure of an arbitrarily moving surface embedded in the flow was proposed with a heavy emphasis on image processing methods. The costs associated with the experimental apparatus were reduced by recording the surface and the trace particles at one image plane without the use of additional cameras or illumination devices. An optimal exposure time for surface and particle imaging was identified using red fluorescent tracer particles in conjunction with a long-pass glass filter. The particle image and surface image were then separated using an image separation process that relied on the feature scaling differences between the particles and the surface texture. A feature detection process and a matching process facilitated estimation of the 3D surface points, and the 3D surface structure was modeled by Delaunay triangulation. The particle volume reconstruction algorithm constrained the voxels inside the surface structure to zero values to minimize ghost particle generation. Volume self-calibration was employed to improve the reconstruction quality and the triangulation accuracy. To conserve computing resources in the presence of numerous zero voxels, the MLOS-SMART reconstruction and the direct non-zero voxel cross-correlation method were applied. Three-dimensional experiments that modeled the flows around an eccentric rotating cylinder and a flapping flag were conducted to validate the present technique. 相似文献