Synthesis of the antiepileptic (R)-Stiripentol by a combination of lipase catalyzed resolution and alkene metathesis

The enantiopure (ee >99%) antiepileptic (R)-(+)-Stiripentol has been stereoselectively synthesized via cross metathesis of 5-vinylbenzo[d][1,3]dioxole 1 and (R)-(+)-4,4-dimethylpent-1-en-3-ol (R)-(+)-2. A novel one-pot two-step pathway for the synthesis of 5-vinylbenzo[d][1,3]dioxole 1 starting from 3,4-dihydroxycinnamic acid has been introduced. A lipase catalyzed kinetic resolution access to enantiopure (R)-(+)-4,4-dimethylpent-1-en-3-ol (R)-(+)-2 (ee >99%) has also been developed.     

An equilibrium model of how regulative and normative institutions influence micro-economic and organizational behavior

This paper investigates how pre-existing institutions foster economic development through trade. A non-cooperative game-theoretic model is proposed that combines three strands of social science: economics, political science, and sociology. Idealized market participants follow rational decision theory within a reward structure that embodies two types of institutions. Regulative institutions operate on threat of punishment, and normative institutions on perceptions of what is good and right. This composite model allows a more quantitative analysis of the question, raised by Douglas North, of how societies diverge from the efficient state predicted by classical micro-economics. The main finding is that value can be created by different types of institution even when they are imperfect, and the range of minimum–maximum effectiveness varies with the types of economic transactions that are technologically possible. It is hoped that further refinements of the model will yield greater understanding of how the success of societies and organizations can be predicted by a few simple rules.     

How M?ssbauer spectroscopy can improve Li-ion batteries

In the domain of Li-ion batteries, M?ssbauer spectroscopy is mainly used for the characterization of electrode materials and the analysis of electrochemical reactions. Depending on the properties under investigation, different approaches are often considered, which are based on ex situ, in situ and operando measurements. The specific electrochemical cells and sample preparations used for such measurements are described in this paper. Applications to selected examples of cathode and anode materials are presented in order to show how M?ssbauer spectroscopy, when associated with other techniques, provides essential information to understand the mechanisms and improves the performances of Li-ion batteries.     

Solvothermal synthesis,thermal and adsorption properties of metal-organic frameworks Zn and CoZn(DPB)

Journal of Thermal Analysis and Calorimetry - New mononuclear and hetero-binuclear MOFs derived from the reaction of 1,4-bis[(3,5-dimethyl)pyrazole-4-yl]benzene (H2DPB) with zinc nitrate or mixture...