全文获取类型
收费全文 | 1156篇 |
免费 | 35篇 |
国内免费 | 7篇 |
专业分类
化学 | 867篇 |
晶体学 | 5篇 |
力学 | 21篇 |
数学 | 93篇 |
物理学 | 212篇 |
出版年
2022年 | 17篇 |
2021年 | 10篇 |
2020年 | 22篇 |
2019年 | 11篇 |
2018年 | 16篇 |
2017年 | 12篇 |
2016年 | 21篇 |
2015年 | 14篇 |
2014年 | 22篇 |
2013年 | 40篇 |
2012年 | 47篇 |
2011年 | 71篇 |
2010年 | 31篇 |
2009年 | 18篇 |
2008年 | 63篇 |
2007年 | 76篇 |
2006年 | 75篇 |
2005年 | 58篇 |
2004年 | 65篇 |
2003年 | 55篇 |
2002年 | 27篇 |
2001年 | 23篇 |
2000年 | 17篇 |
1998年 | 15篇 |
1997年 | 23篇 |
1996年 | 25篇 |
1995年 | 12篇 |
1994年 | 8篇 |
1993年 | 15篇 |
1992年 | 11篇 |
1991年 | 16篇 |
1990年 | 21篇 |
1989年 | 7篇 |
1988年 | 13篇 |
1986年 | 8篇 |
1985年 | 9篇 |
1984年 | 8篇 |
1983年 | 12篇 |
1982年 | 13篇 |
1981年 | 6篇 |
1980年 | 9篇 |
1979年 | 10篇 |
1978年 | 10篇 |
1977年 | 16篇 |
1976年 | 19篇 |
1975年 | 20篇 |
1974年 | 9篇 |
1973年 | 8篇 |
1971年 | 7篇 |
1932年 | 7篇 |
排序方式: 共有1198条查询结果,搜索用时 15 毫秒
91.
92.
A new strategy for the combinatorial synthesis of new materials has been developed through the consecutive application of an Ugi 4CC reaction and a ring-opening metathesis polymerization (ROMP) reaction. Norbornenyl aldehydes and carboxylic acids could be used in the Ugi MCR to give highly diverse monomers that were converted to the corresponding polymers by exposure to the second-generation Grubbs' catalyst. These polymers have structural features reminiscent of polypeptides and the process could be extended to the preparation of chiral materials. 相似文献
93.
Lorenzato M Abboud P Lechki C Browarnyj F O'Donohue MF Ploton D Adnet JJ 《Micron (Oxford, England : 1993)》2000,31(2):151-159
There are two ways of measuring the cell proliferation. The first one consists of quantifying the number of cycling cells with the help of antibodies directed against cells either in G1, S, G2 or M phase. The second way is to assess the cell cycle duration by the quantification of AgNOR proteins. Measuring both the features on the same slide represents an attractive way to tackle the proliferating activity of a cell culture or a tumor. Here, we propose a MIB-1 and AgNOR double staining method especially adapted to image cytometry measurement using MIB-1 antibody coupled to FITC in order to avoid the thresholding problems encountered with such a multilabeling technique. We have applied this new method on a series of 39 breast cancer cases, with at least 4 years follow-up, in order to determine the prognosis significance of this measurement. MIB-1 alone is not linked to prognosis, while the global mean AgNOR area is significantly linked to prognosis in terms of development of visceral metastasis or death. However, the global mean AgNOR area is insufficient to determine the time limit of appearance of metastasis or relapse. Our results clearly demonstrate that a high mean AgNOR area within a cell population having a high MIB-1 index can discern tumors with a high metastatic potential. By multiplying AgNOR area by the percentage of MIB-1 positive cells we calculate the proliferative activity, P, which brings very important information concerning the time limit of relapse. 相似文献
94.
Li Yang Paul W. May Lei Yin James A. Smith Keith N. Rosser 《Journal of nanoparticle research》2007,9(6):1181-1185
Crystalline carbon nitride nanopowders and nanorods have been successfully synthesized at room temperature and pressure using
the novel technique of pulsed laser ablation of a graphite target in liquid ammonia solution. High-resolution transmission
electron microscopy (HRTEM), selected area electron diffraction (SAED), and Fourier transform infrared spectroscopy (FTIR)
were used to systematically study the morphology, nanostructure and chemical bonding. The experimental composition and structure
of the nanoparticles are consistent with the theoretical calculations for α-C3N4. After 2 h ablation the particles had a size distribution ∼8–12 nm, whereas after 5 h ablation the particles had grown into
nanorod-like structures with a crystalline C3N4 tip. A formation mechanism for these nanorods is proposed whereby nanoparticles are first synthesized via rapid formation
of an embryonic particle, followed by a slow growth, eventually leading to a one-dimensional nanorod structure. 相似文献
95.
The Canadian Light Source (CLS) is constructing two beamlines for Infrared Spectroscopy using synchrotron radiation (IRSR). One will supply mid-Infrared (2–25 μ) light to a Fourier Transform Infrared (FTIR) spectrometer and microscope for biological applications. The second will have a high resolution FTIR spectrometer for gas-phase and surface spectroscopy in the far-Infrared (beyond 25 μ). The Infrared beamlines will use dipole bending magnet radiation from a special bend magnet port design which provides a 50 mrad square acceptance. Issues with the first mirror and photon mask design, as well as the beamline layout and features are discussed. 相似文献
96.
Wyche TP Hou Y Braun D Cohen HC Xiong MP Bugni TS 《The Journal of organic chemistry》2011,76(16):6542-6547
A marine Verrucosispora sp. isolated from the sponge Chondrilla caribensis f. caribensis was found to produce thiocoraline, a potent cytotoxic compound. Five new analogs of thiocoraline were isolated and represent the first analogs of thiocoraline. 22'-Deoxythiocoraline (2), thiochondrilline C (5), and 12'-sulfoxythiocoraline (6) demonstrated significant cytotoxicity against the A549 human cancer cell line with EC(50) values of 0.13, 2.86, and 1.26 μM, respectively. The analogs provide insight into the SAR and biosynthesis of thiocoraline. The DP4 probability method was used to analyze ab initio NMR calculations to confirm stereochemical assignments. 相似文献
97.
Copping R Gaunt AJ May I Sharrad CA Collison D Helliwell M Fox OD Jones CJ 《Chemical communications (Cambridge, England)》2006,(36):3788-3790
(NH4)14Na4[(Np3W4O15)(H2O)3(BiW9O33)3].62H2O (1) and (NH4)14.5Na3.5[(Np3W4O15)(H2O)3(SbW9O33)3].40.5H2O (2) each contain three neptunyl(v) moieties encapsulated within heteropolyoxotungstate frameworks in which axial {NpO2}+ oxygens form one face of a WO6 octahedron. 相似文献
98.
99.
Hwang-Hsing Chen Jesse A. May Vincent M. Lynch 《Journal of heterocyclic chemistry》1999,36(1):249-256
A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonarnide 6,6-dioxides. These cyclic vinyl sulfones readily underwent addi tion to give predominately that 4,5-cis addition product. 相似文献
100.