全文获取类型
收费全文 | 574篇 |
免费 | 26篇 |
国内免费 | 6篇 |
专业分类
化学 | 424篇 |
晶体学 | 8篇 |
力学 | 31篇 |
数学 | 59篇 |
物理学 | 84篇 |
出版年
2024年 | 1篇 |
2023年 | 3篇 |
2022年 | 13篇 |
2021年 | 21篇 |
2020年 | 14篇 |
2019年 | 15篇 |
2018年 | 18篇 |
2017年 | 12篇 |
2016年 | 17篇 |
2015年 | 15篇 |
2014年 | 25篇 |
2013年 | 40篇 |
2012年 | 53篇 |
2011年 | 37篇 |
2010年 | 27篇 |
2009年 | 31篇 |
2008年 | 29篇 |
2007年 | 37篇 |
2006年 | 25篇 |
2005年 | 31篇 |
2004年 | 24篇 |
2003年 | 25篇 |
2002年 | 25篇 |
2001年 | 7篇 |
2000年 | 15篇 |
1999年 | 3篇 |
1998年 | 3篇 |
1997年 | 4篇 |
1996年 | 11篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1991年 | 5篇 |
1990年 | 1篇 |
1986年 | 1篇 |
1985年 | 4篇 |
1984年 | 1篇 |
1979年 | 1篇 |
1961年 | 1篇 |
排序方式: 共有606条查询结果,搜索用时 15 毫秒
601.
Iman Fatima Akhtar Rasul Shahid Shah Malik Saadullah Nayyer Islam Ahmed Khames Ahmad Salawi Muhammad Masood Ahmed Yosif Almoshari Ghulam Abbas Mohammed A. S. Abourehab Sajid Mehmood Khan Zunera Chauhdary Meshal Alshamrani Nader Ibrahim Namazi Demiana M. Naguib 《Molecules (Basel, Switzerland)》2022,27(9)
The occurrence of fungal infections has increased over the past two decades. It is observed that superficial fungal infections are treated by conventional dosage forms, which are incapable of treating deep infections due to the barrier activity possessed by the stratum corneum of the skin. This is why the need for a topical preparation with advanced penetration techniques has arisen. This research aimed to encapsulate fluconazole (FLZ) in a novasome in order to improve the topical delivery. The novasomes were prepared using the ethanol injection technique and characterized for percent entrapment efficiency (EE), particle size (PS), zeta potential (ZP), drug release, Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and antifungal activity. The FN7 formulation with 94.45% EE, 110 nm PS and −24 ZP proved to be the best formulation. The FN7 formulation showed a 96% release of FLZ in 8 h. FTIR showed the compatibility of FLZ with excipients and DSC studies confirmed the thermal stability of FLZ in the developed formulation. The FN7 formulation showed superior inhibition of the growth of Candida albicans compared to the FLZ suspension using a resazurin reduction assay, suggesting high efficacy in inhibiting fungal growth. 相似文献
602.
Salama A. Salama Zarraq E. AL-Faifi Mostafa F. Masood Yasser A. El-Amier 《Molecules (Basel, Switzerland)》2022,27(10)
The objective of this study was to assess the biological potency and chemical composition of Rumex vesicarius aboveground parts using GC–MS. In this approach, 44 components were investigated, comprising 99.99% of the total volatile compounds. The major components were classified as fatty acids and lipids (51.36%), oxygenated hydrocarbons (33.59%), amines (7.35%), carbohydrates (6.06%), steroids (1.21%), and alkaloids (0.42%). The major components were interpreted as 1,3-dihydroxypropan-2-yl oleate (oxygenated hydrocarbons, 18.96%), ethyl 2-hydroxycyclohexane-1-carboxylate (ester of fatty acid, 17.56%), and 2-propyltetrahydro-2H-pyran-3-ol (oxygenated hydrocarbons, 11.18%). The DPPH antioxidant activity of the extracted components of R. vesicarius verified that the shoot extract was the most potent with IC50 = 28.89 mg/L, with the percentages of radical scavenging activity at 74.28% ± 3.51%. The extracted plant, on the other hand, showed substantial antibacterial activity against the diverse bacterial species, namely, Salmonella typhi (23.46 ± 1.69), Bacillus cereus (22.91 ± 0.96), E. coli (21.07 ± 0.80), and Staphylococcus aureus (17.83 ± 0.67). In addition, the extracted plant was in vitro assessed as a considerable anticancer agent on HepG2 cells, in which MTT, cell proliferation cycle, and DNA fragmentation assessments were applied on culture and treated cells. The larvicidal efficacy of the extracted plant was also evaluated against Aedes aegypti, the dengue disease vector. As a result, we may infer that R. vesicarius extract increased cytocompatibility and cell migratory capabilities, and that it may be effective in mosquito control without causing harm. 相似文献
603.
The newly discovered crystal structures of CH3(OCH2CH2)OCH3(LiCF3SO3)2, monoglyme:(LiTf)2, and CH3(OCH2CH2)3OCH3(LiCF3SO3)2, triglyme:(LiTf)2, are briefly described. The coordination of lithium cations and the CF3SO3− anions in these structures is compared with the cation and anion coordination in the crystalline phase of high molecular weight P(EO)3LiCF3SO3. Comparison is also made with the previously reported crystalline phase of CH3(OCH2CH2)2OCH3LiCF3SO3, diglyme:LiTf. A tendency to form trans-gauche-trans conformations for the bond order -O-C-C-O- is noted in adjacent ethylene oxide sequences interacting with a five-coordinate lithium ion. 相似文献
604.
605.
606.
Carsten E. Seyfert Christoph Porten Dr. Biao Yuan Selina Deckarm Dr. Fabian Panter Dr. Chantal D. Bader Janetta Coetzee Felix Deschner Dr. Kamaleddin H. M. E. Tehrani Prof. Dr. Paul G. Higgins Prof. Dr. Harald Seifert Prof. Dr. Thomas C. Marlovits Dr. Jennifer Herrmann Prof. Dr. Rolf Müller 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2023,135(2):e202214094