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971.
Cord M Sirjean B Fournet R Tomlin A Ruiz-Lopez M Battin-Leclerc F 《The journal of physical chemistry. A》2012,116(24):6142-6158
This paper revisits the primary reactions involved in the oxidation of n-butane from low to intermediate temperatures (550-800 K) including the negative temperature coefficient (NTC) zone. A model that was automatically generated is used as a starting point and a large number of thermochemical and kinetic data are then re-estimated. The kinetic data of the isomerization of alkylperoxy radicals giving (?)QOOH radicals and the subsequent decomposition to give cyclic ethers has been calculated at the CBS-QB3 level of theory. The newly obtained model allows a satisfactory prediction of experimental data recently obtained in a jet-stirred reactor and in rapid compression machines. A considerable improvement of the prediction of the selectivity of cyclic ethers is especially obtained compared to previous models. Linear and global sensitivity analyses have been performed to better understand which reactions are of influence in the NTC zone. 相似文献
972.
Madrigal-Santillán E Fragoso-Antonio S Valadez-Vega C Solano-Solano G Pérez CZ Sánchez-Gutiérrez M Izquierdo-Vega JA Gutiérrez-Salinas J Esquivel-Soto J Esquivel-Chirino C Sumaya-Martínez T Fregoso-Aguilar T Mendoza-Pérez J Morales-González JA 《Molecules (Basel, Switzerland)》2012,17(4):4435-4451
There are few reports that demonstrate the antigenotoxic potential of cranberries. Although the types of berry fruits consumed worldwide are many, this paper focuses on cranberries that are commonly consumed in Mexico (Vaccinium macrocarpon species). The purpose of the present study is to determine whether cranberry ethanolic extract (CEE) can prevent the DNA damage produced by benzo[a]pyrene (B[a]P) using an in vivo mouse peripheral blood micronucleus assay. The experimental groups were organized as follows: a negative control group (without treatment), a positive group treated with B[a]P (200 mg/kg), a group administered with 800 mg/kg of CEE, and three groups treated with B[a]P and CEE (200, 400, and 800 mg/kg) respectively. The CEE and benzo[a]pyrene were administered orally for a week, on a daily basis. During this period the body weight, the feed intake, and the determination of antigenotoxic potential were quantified. At the end of this period, we continued with the same determinations for one week more (recovery period) but anymore administration of the substances. The animals treated with B[a]P showed a weight increase after the first week of administration. The same phenomenon was observed in the lots combined with B[a]P and CEE (low and medium doses). The dose of 800 mg/kg of CEE showed similar values to the control group at the end of the treatment period. In the second part of the assay, when the substances were not administered, these experimental groups regained their normal weight. The dose of CEE (800 mg/kg) was not genotoxic nor cytotoxic. On the contrary, the B[a]P increases the frequency of micronucleated normochromatic erythrocytes (MNNE) and reduces the rate of polychromatic erythrocytes (PE) at the end of the treatment period. With respect to the combined lots, a significant decrease in the MN rate was observed from the sixth to the eighth day of treatment with the two high doses applied; the highest protection (60%) was obtained with 800 mg/kg of CEE. The same dose showed an anticytotoxic effect which corresponded to an improvement of 62.5% in relation to the animals administered with the B[a]P. In the second period, all groups reached values that have been seen in the control group animals. Our results suggest that the inhibition of clastogenicity of the cranberry ethanolic extract against B[a]P is related to the antioxidant capacity of the combination of phytochemicals present in its chemical composition. 相似文献
973.
Boone MN De Witte Y Dierick M Almeida A Van Hoorebeke L 《Microscopy and microanalysis》2012,18(2):399-405
In conventional X-ray microtomography (μCT), the three-dimensional (3D) distribution of the attenuation coefficient of X-rays is measured and reconstructed in a 3D volume. As spatial resolution increases, the refraction of X-rays becomes a significant phenomenon in the imaging process. Although this so-called phase contrast was initially a cumbersome feature in lab-based μCT, special phase retrieval algorithms were developed to exploit these effects. Clear advantages in terms of visualization and analysis can be seen when phase retrieval algorithms are applied, including an increased signal-to-noise ratio. In this work, this is demonstrated both on simulated and measured data. 相似文献
974.
975.
María del Mar Castro López M.C. Cela PérezMaría Sonia Dopico García José Manuel López VilariñoMaría Victoria González Rodríguez Luis F. Barral Losada 《Analytica chimica acta》2012
Molecularly imprinted polymer (MIP) for solid extraction and preconcentration of catechins have been successfully prepared by a thermal polymerization method using quercetin as template, 4-vinylpyridine as functional monomer and ethylene glycol dimethacrylate as crosslinker. A solution mixture of acetone and acetonitrile was used as porogen. Systematic investigations of the influence of monomer, cross-linker, porogen, as well as polymerization conditions on the properties of the MIPs were carried out. The quercetin MIPs were evaluated according to their selective recognition properties for quercetin, structurally related compounds (catechin, epigallocatechin gallate and epicatechin) and a unrelated compound of similar molecular size (α-tocopherol). Good binding was observed for quercetin, catechin and epigallocatechin gallate with an optimized MIP in a solid phase extraction system. Adsorption and kinetic characteristics were evaluated for catechins which indicated that the synthesized polymer had high adsorption capacity and contained homogeneous binding sites. Chemical and morphological characterization of the MIP was investigated by FTIR, SEM and BET, which confirmed a high degree of polymerization. Finally, the MIP was successfully applied to the clean-up and preconcentration of catechins from several natural samples. 相似文献
976.
977.
Reactions of 3-substituted-5-amino-1H-pyrazoles with 2-acetylcyclopentanone or 2-ethoxycarbo-nylcyclopentanone lead to the regioselective formation of a new series of cyclopentapyrazolo[1,5-a]pyrimidines in good yields. When 2-acetylbutyrolactone was used, the reaction provided 6-(2-hydroxyethyl)pyrazolo[1,5-a]pyrimidinone and/or the intermediate (3Z)-3-{1-[(5-R-1H-pyrazol-3-yl)amino]ethylidene}-4,5-dihydrofuranone. This indicates that the cyclization proceeds with butyrolactone ring opening as the last step. Several aspects of this regioselective reaction, including mechanistic and structural studies, are considered. 相似文献
978.
Interaction studies between photochromic spiropyrans and transition metal cations: the curious case of copper 总被引:1,自引:0,他引:1
A series of four spiropyrans bearing different substituents on the indolic nitrogen were synthesized and their capability of binding mono and bivalent transition metal cations in solution was assessed via UV-visible absorption spectroscopy. All the compounds responded selectively to the presence of Cu(ii) ions producing intense absorption bands in the visible region of their spectra. Bidimensional (1)H-NMR and MALDI-TOF MS spectroscopies revealed the formation of SP dimers mediated by Cu(ii). This is the first example of cross-coupling mediated by copper(ii) in mild conditions causing the symmetric dimerization of spiropyran dyes. 相似文献
979.
Let ${\phi(x)}$ be a rational function of degree >?1 defined over a number field K and let ${\Phi_{n}(x,t) = \phi^{(n)}(x)-t \in K(x,t)}$ where ${\phi^{(n)}(x)}$ is the nth iterate of ${\phi(x)}$ . We give a formula for the discriminant of the numerator of Φ n (x, t) and show that, if ${\phi(x)}$ is postcritically finite, for each specialization t 0 of t to K, there exists a finite set ${S_{t_0}}$ of primes of K such that for all n, the primes dividing the discriminant are contained in ${S_{t_0}}$ . 相似文献
980.
Manuel J.S. Monte Sónia P. Pinto Ana I.M.C. Lobo Ferreira Luísa M.P.F. Amaral Vera L.S. Freitas Maria D.M.C. Ribeiro da Silva 《The Journal of chemical thermodynamics》2012,45(1):53-58
This work reports new experimental thermodynamic results on fluorene. Vapor pressures of both crystalline and liquid phases were measured using a pressure gauge (capacitance diaphragm manometer) and Knudsen effusion methods over a wide temperature range (292.20 to 412.16) K yielding accurate determination of enthalpy and entropy of sublimation and of vaporization. The enthalpy of sublimation was also determined using Calvet microcalorimetry. The enthalpy of fusion was derived from vapor pressure results and from d.s.c. experiments. Static bomb calorimetry was used to determine the enthalpy of combustion of fluorene from which the standard enthalpy of formation in the crystalline phase was calculated. The enthalpy of formation in the gaseous phase was calculated combining the result derived for the crystalline phase with the enthalpy of sublimation. 相似文献