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51.
In this work, we study a new kind of dark energy (DE), which is named as "Yang-Mills condensate" (YMC). We study the stability and wde-w'de analysis of YMC DE model. Then we correspond it with quintessence, k-essence, tachyon, phantom, dilaton, DBI-essence and hessence scalar field models of DE in FRW spacetime to reconstruct potentials as well as the dynamics for these scalar fields for describing the acceleration of the universe. We also analyze the models in graphically to interpret the nature of the scalar fields and corresponding potentials. 相似文献
52.
Debnath J Dasgupta S Pathak T 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(6):1618-1627
Ribonuclease?A (RNase A) serves as a convenient model enzyme in the identification and development of inhibitors of proteins that are members of the ribonuclease superfamily. This is principally because the biological activity of these proteins, such as angiogenin, is linked to their catalytic ribonucleolytic activity. In an attempt to inhibit the biological activity of angiogenin, which involves new blood vessel formation, we employed different dinucleosides with varied non-natural backbones. These compounds were synthesized by coupling aminonucleosides with dicarboxylic acids and amino- and carboxynucleosides with an amino acid. These molecules show competitive inhibition with inhibition constant (K(i)) values of (59±3) and (155±5) μM for RNase A. The compounds were also found to inhibit angiogenin in a competitive fashion with corresponding K(i) values in the micromolar range. The presence of an additional polar group attached to the backbone of dinucleosides was found to be responsible for the tight binding with both proteins. The specificity of different ribonucleolytic subsites were found to be altered because of the incorporation of a non-natural backbone in between the two nucleosidic moieties. In spite of the replacement of the phosphate group by non-natural linkers, these molecules were found to selectively interact with the ribonucleolytic site residues of angiogenin, whereas the cell binding site and nuclear translocation site residues remain unperturbed. Docked conformations of the synthesized compounds with RNase A and angiogenin suggest a binding preference for the thymine-adenine pair over the thymine-thymine pair. 相似文献
53.
54.
Dr. Joy Debnath Prof. Swagata Dasgupta Prof. Tanmaya Pathak 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(6):1618-1627
Ribonuclease A (RNase A) serves as a convenient model enzyme in the identification and development of inhibitors of proteins that are members of the ribonuclease superfamily. This is principally because the biological activity of these proteins, such as angiogenin, is linked to their catalytic ribonucleolytic activity. In an attempt to inhibit the biological activity of angiogenin, which involves new blood vessel formation, we employed different dinucleosides with varied non‐natural backbones. These compounds were synthesized by coupling aminonucleosides with dicarboxylic acids and amino‐ and carboxynucleosides with an amino acid. These molecules show competitive inhibition with inhibition constant (Ki) values of (59±3) and (155±5) μM for RNase A. The compounds were also found to inhibit angiogenin in a competitive fashion with corresponding Ki values in the micromolar range. The presence of an additional polar group attached to the backbone of dinucleosides was found to be responsible for the tight binding with both proteins. The specificity of different ribonucleolytic subsites were found to be altered because of the incorporation of a non‐natural backbone in between the two nucleosidic moieties. In spite of the replacement of the phosphate group by non‐natural linkers, these molecules were found to selectively interact with the ribonucleolytic site residues of angiogenin, whereas the cell binding site and nuclear translocation site residues remain unperturbed. Docked conformations of the synthesized compounds with RNase A and angiogenin suggest a binding preference for the thymine–adenine pair over the thymine–thymine pair. 相似文献
55.
Samarpita Bhattacharya Ujjal Debnath 《International Journal of Theoretical Physics》2012,51(2):565-576
Here we generalize the results of the work of Myung () in modified Chaplygin gas model and tachyonic field model. Here we have studied the thermodynamical behavior and the equation
of state in terms of volume and temperature for both models. We have used the solution and the corresponding equation of state
of our previous work (Chattopadhyay et al., Astrophys. Space Sci. 314:41, 2008). for tachyonic field model. We have also studied the thermodynamical stability using thermal equation of state for the tachyonic
field model and have shown that there is no critical points during thermodynamical expansion. The determination of T
∗ due to expansion for the tachyonic field have been discussed by assuming some initial conditions. Here, the thermal quantities
have been investigated using some reduced parameters. 相似文献
56.
The paper deals with the interaction between three Griffith cracks propagating under antiplane shear stress at the interface of two dissimilar infinite elastic half-spaces. The Fourier transform technique is used to reduce the elastodynamic problem to the solution of a set of integral equations which has been solved by using the finite Hilbert transform technique and Cooke’s result. The analytical expressions for the stress intensity factors at the crack tips are obtained. Numerical values of the interaction effect have been computed for and results show that interaction effects are either shielding or amplification depending on the location of each crack with respect to other and crack tip spacing. 相似文献
57.
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59.
An initial value investigation is made of the motion of an incompressible viscous conducting fluid with embedded small spherical particles bounded by two infinite rigid non-conducting plates. The flow is generated in the fluid-particle system due to rectilinear oscillations of given frequencies superimposed on the plates in presence of an external transverse magnetic field. The operational method is used to derive exact solutions for the fluid and the particle velocities and the wall shear stress. It is shown that the effect of the dust particles on the fluid velocity depends on the time periods of the oscillating plates. When the time-periods are small, i.e., when the plates oscillate with high frequency, the fluid motion is found to be retarded by the particles. However, when the plates oscillate with larger time periods (smaller frequencies), the fluid velocity is increased by the presence of the particles at the early stage of the motion, and this effect persists until the equilibrium is reached when the particles exert their influence to resist the flow. 相似文献
60.
TheSU(3) F breaking effects are considered to fit the set of anomalous Ward identities in QCD. The solutions are then analysed and compared with a recent work that also deals with such identities. 相似文献