DNP-EPR多功能谱仪中微波桥的设计与实现

在自主研制的动态核极化（Dynamic Nuclear Polarization,DNP）分子影像装置的基础上,提出了一种集DNP和电子顺磁共振（Electron Paramagnetic Resonance,EPR）于一体的多功能谱仪,并对其中的关键部件之一--微波桥进行了设计.微波桥的引入,实现了DNP微波发射机的集成化,以及在DNP谱仪基础上的EPR功能扩展.通过结构设计、电路仿真及系统测试,完成了高频谱纯度、高动态范围的微波发射机以及低噪声系数的微波检测系统的设计与制作.并通过DNP增强实验以及连续波EPR实验对微波桥的性能进行了验证.     

Design,Synthesis, and Evaluation of Tetraethylene Glycol Tethered Isatin–Coumarin Hybrids as Novel Anticancer Agents

Herein, we report the design and synthesis of a new set of tetraethylene glycol tethered isatin–coumarin hybrids 7a – l as anticancer agents. Results revealed that all the synthesized hybrids showed no or weak activities against their in vitro antitumor activities against drug‐sensitive HepG2, Hela, A549, DU145, SKOV3, and MCF‐7 as well as drug‐resistant MCF‐7/DOX (doxorubicin‐resistant MCF‐7) human cancer cell lines. The structure–activity relationship was also discussed, and the enriched structure–activity relationship may pave the way for further rationale design of this kind of hybrids.     

Auq+(q=53-47)激光等离子体的辐射复合速率系数

辐射复合过程在超组态碰撞辐射（SCROLL）模型中真实模拟非局域热动力学平衡（non-LTE）高Z材料Au激光等离子体M带谱5f-3d跃迁中各种复杂离子的电离态特性是一个主要过程。基于准相对论多组态Hartree-Fock理论和扭曲波近似,采用组态平均的方法,从头计算了金M带类铁金离子-类锗金离子的辐射复合速率系数,计算过程中包含了大量的单激发和双激发态,结果表明高Z元素由于自电离能级的广泛分布和复杂的级联效应,致使高Z元素的辐射复合系数不同于低Z元素的,其计算结果可用来模拟Au的激光等离子体M带5f-3d跃迁的平均电离度和电荷态分布及能级布居数。     

Central limit theorem for integrated square error of kernel estimators of spherical density

LetX ₁,…,X _n be iid observations of a random variableX with probability density functionf(x) on the q-dimensional unit sphere Ω_q in R^q+1,q ⩾ 1. Let be a kernel estimator off(x). In this paper we establish a central limit theorem for integrated square error off _n under some mild conditions.     

RATES OF A.S.CONVERGENCE OF THE ESTIMATION OF ERROR VARIANCE IN LINEAR MODELS

Under appropriate conditions we obtain the best rates of a.s.convergence of estimates5_n~2 of error variance σ~2 and establish the law of iterated logarithm     

Nonlinear spinor theory and Weinberg's model

It is shown that the formalism for eliminating vacuum degeneracy can be used to reduce the Heisenberg-Ivanenko nonlinear spinor Lagrangian to a Weinberg-type model Lagrangian of the weak and electromagnetic interactions.     

A novel plasmonic refractive index sensor based on gold/silicon complementary grating structure

A novel complementary grating structure is proposed for plasmonic refractive index sensing due to its strong resonance at near-infrared wavelength.The reflection spectra and the electric field distributions are obtained via the finite-difference time-domain method.Numerical simulation results show that multiple surface plasmon resonance modes can be excited in this novel structure.Subsequently,one of the resonance modes shows appreciable potential in refractive index sensing due to its wide range of action with the environment of the analyte.After optimizing the grating geometric variables of the structure,the designed structure shows the stable sensing performance with a high refractive index sensitivity of 1642 nm per refractive index unit(nm/RIU)and the figure of merit of 409 RIU^-1.The promising simulation results indicate that such a sensor has a broad application prospect in biochemistry.     

Efficient manipulation of terahertz waves by multi-bit coding metasurfaces and further applications of such metasurfaces

Benefiting from the unprecedented superiority of coding metasurfaces at manipulating electromagnetic waves in the microwave band,in this paper,we use the Pancharatnam-Berry(PB)phase concept to propose a high-efficiency reflectivetype coding metasurface that can arbitrarily manipulate the scattering pattern of terahertz waves and implement many novel functionalities.By optimizing the coding sequences,we demonstrate that the designed 1-,2-,and 3-bit coding metasurfaces with specific coding sequences have the strong ability to control reflected terahertz waves.The two proposed1-bit coding metasurfaces demonstrate that the reflected terahertz beam can be redirected and arbitrarily controlled.For normally incident x-and y-polarized waves,a 10 d B radar cross-section(RCS)reduction can be achieved from 2.1 THz to5.2 THz using the designed 2-bit coding metasurface.Moreover,two kinds of orbital angular momentum(OAM)vortex beams with different moduli are generated by a coding metasurface using different coding sequences.Our research provides a new degree of freedom for the sophisticated manipulation of terahertz waves,and contributes to the development of metasurfaces towards practical applications.     

UPLC–Q–TOF–MS/MS Analysis of Phenolic Compounds from the Fruit of Cephalostachyum fuchsianum Gamble and Their Antioxidant and Cytoprotective Activities

Bamboo is a widely distributed graminaceous plant in China and is a potential source of bioactive substances. Incidentally, bamboo’s fruit is rich in phytochemicals such as polyphenols and flavonoids, which are significant to human health. In this study, we identified the phenolic compounds of the fruit and investigated the antioxidant activities of Cephalostachyum fuchsianum Gamble (CFG) fruit polyphenols with in vitro and in vivo tests for the first time. UPLC–Q–TOF–MS/MS analysis results showed that the fruit contained 43 phenolic compounds, including 7 hydroxybenzoic acids, 12 flavonoids, 7 coumarins, 10 hydroxycinnamic acids, 1 terpenoid, and 5 lignans. The TPC of SP extracts was higher than that of IBPs extracts in FP and FF. The SP extracts in FP showed better antioxidant activities in vitro compared to those in FF. In addition, polyphenols from CFG fruits protected against H₂O₂-induced oxidative damage in HepG2 cells, and the protective effect of polyphenols in FP was superior to that in FF. The analysis results showed that CFG fruit has great potential in exploiting natural chemical substances, which can provide valuable pieces of information for the further development and utilization of CFG.     

孔缝对金属腔体强电磁脉冲耦合特性影响研究

核电磁脉冲和高功率微波等强电磁脉冲易造成电子设备功能失效甚至损毁,在实际工程实施中用金属腔体对电子设备进行屏蔽是常用的强电磁脉冲抑制手段。基于电磁仿真计算,对含矩形孔缝金属腔体的强电磁脉冲耦合特性进行了系统研究,阐述了孔缝宽长比、腔体尺寸等因素对多种不同类型强电磁脉冲（核电磁脉冲、宽带高功率微波、窄带高功率微波）作用下腔体内耦合场的影响;并以此为基础,重点分析了强电磁脉冲与含孔缝金属腔体之间的作用机制。研究结果表明：不同类型强电磁脉冲耦合信号差异明显,金属腔体对强电磁脉冲的响应是腔体谐振模式、孔缝谐振频率与强电磁脉冲共同作用的结果;当腔体谐振模式、孔缝谐振频率在强电磁脉冲的带内时,腔体内部的耦合场会出现增强效应;特别地,腔体与孔缝间的相互作用还可造成腔体与缝隙的谐振频率发生偏移。因此,在为电子设备设计金属屏蔽外壳时,应基于不同强电磁脉冲的频带范围,对腔体与孔缝的尺寸进行综合设计,抑制腔体、孔缝谐振及谐振频率偏移,提升其强电磁脉冲防护性能。