(Me2NH2)[(Ph3Sn)3(MoO4)2], ein Triorganozinnmolybdat mit Schichtstruktur

(Me₂NH₂)[(Ph₃Sn)₃(MoO₄)₂], a Triorganotin Molybdate with Layer Structure The reaction of [(Ph₃Sn)₂MoO₄] with (Me₂NH₂)Cl in an acetonitrile/water mixture leads to the formation of (Me₂NH₂)[(Ph₃Sn)₃(MoO₄)₂] ( 1 ). ( 1 ) crystallizes in the space group Pca2₁ with a = 1967.0(4), b = 1353.1(2) and c = 2176.6(5) pm. In the crystal structure of 1 Ph₃SnO₂ bipyramides and MoO₄ tetrahedra are linked by corner sharing to give a layer structure. Additionally the layers are connected by O···H···N hydrogen bridges between MoO₄ groups and [Me₂NH₂]⁺ ions to give a 3D network structure.     

Contribution à la phytochimie du genre Gentiana. VII. Etude des composés flavoniques et xanthoniques dans les feuilles de Gentiana vernaL. (1ère communication)

A new xanthone-O-glycoside, the 1,7-dihydroxy-3-methoxyxanthone-8-O-β-D-glucopyranoside ( 7 ), has been isolated from the leaves of Gentiana verna L. by means of column chromatography on polyamid. Six known xanthones: 1-hydroxy-3,7,8-trimethoxyxanthone-1-O-primerveroside ( 2 ); 1,7,8-trihydroxy-3-methoxyxanthone ( 3 ); 7-hydroxy-3,8-dimethoxyxanthone-1-O-primeveroside ( 4 ); 7,8-dihydroxy-3-methoxyxanthone-1-O-primeveroside ( 5 ); mangiferin 6 and the flavone C-glycoside isoorientin 8 have also been isolated and identified.     

Supernovae and the Arrow of Time

Supernovae are explosions of stars and are a central problem in astrophysics. Rayleigh–Taylor (RT) and Richtmyer–Meshkov (RM) instabilities develop during the star’s explosion and lead to intense interfacial RT/RM mixing of the star materials. We handle the mathematical challenges of the RT/RM problem based on the group theory approach. We directly link the conservation laws governing RT/RM dynamics to the symmetry-based momentum model, derive the model parameters, and find the analytical solutions and characteristics of RT/RM dynamics with variable accelerations in the linear, nonlinear and mixing regimes. The theory outcomes explain the astrophysical observations and yield the design of laboratory experiments. They suggest that supernova evolution is a non-equilibrium process directed by the arrow of time.     

A rapid and selective HPLC‐UV method for the quantitation of efavirenz in plasma from patients on concurrent HIV/AIDS and tuberculosis treatments

Owing to heterogeneity in therapeutic response, efavirenz is of research and clinical interest. There is a need to quantitate it using noncostly and selective methods. A method for efavirenz quantitation in plasma containing HIV and tuberculosis drugs was developed. Chromatographic separation was carried out using a C₁₈ column. The mobile phase consisted of 0.1% formic acid and acetonitrile, and was pumped at a flow rate of 0.3 mL/min. Efavirenz and ritonavir (internal standard) were monitored at 247 nm. Plasma proteins were precipitated by centrifugation. The analysis time was 6 min. The response was linear (r = 0.9997). The accuracy ranged between 98 and 115% (intraday) and between 99 and 117% (interday). The precision ranged from 1.670 to 4.087% (intraday) and from 3.447 to 13.347% (interday). Recovery ranged from 98 to 132%. Stability ranged between 99 and 123%. The selectivity was proven by analysis of drugs used for the management of HIV/AIDS and tuberculosis. Plasma sample analysis showed an efavirenz retention time of 5.57 min and a peak plasma concentration of 2.4 µg/mL occurring at 2 h. This method is rapid and selective, and thus suitable for monitoring efavirenz in patients with HIV/AIDS alone or co‐infected with tuberculosis in a less resourced setting. Copyright © 2013 John Wiley & Sons, Ltd.     

Chaotic dynamics of resistively coupled DC-driven distinct Josephson junctions and the effects of circuit parameters

Two distinct Josephson junctions (JJs) connected with a constant coupling resistance R_cp are theoretically considered to investigate the overall dynamics below and above the critical current I_c. The circuit model of the device is driven by two DC current sources, I₁ and I₂. Each junction is characterized by a nonlinear resistive–capacitive junction (NRCSJ). Having constructed the circuit model, time-dependent simulations are carried out for a variety of control parameter sets. Common techniques such as bifurcation diagrams, two-dimensional attractors and Lyapunov exponents are applied for the determination of chaotic as well as periodic dynamics of the superconducting junction devices. According to the findings, two states (namely superconducting and ordinary conducting) are determined as functions of the source currents. The chaotic current which flows through R_cp exhibits a very rich behavior depending on the source currents I₁ and I₂ and junction capacitances C₁ and C₂. The device characteristics are summarized by a number of three-dimensional phase diagrams in the parameter space. In addition, for certain parameters, hyper-chaotic cases with two positive Lyapunov exponents are encountered. In contrast to earlier studies claiming the need for a sinusoidal feeding current for generating a chaotic signal, our circuitry can easily generate one via a DC source.     

Port-Hamiltonian representation for pdes with second-order derivatives in the energy density

In this contribution we consider a port-Hamiltonian setting for partial differential equations. A crucial property of this system class is the property to be able to link a power balance relation to the structure of the equations. However, one has to take into account also the effects of energy flows via the boundary. This is straightforward when the Hamiltonian depends on derivative variables of first order, e.g. by using integration by parts. If second-order derivatives appear then integration by parts cannot be used without due care, thus we suggest an approach by using the so-called Cartan-form. We visualize the derivation of a power balance relation by using the Kirchhoff plate as an example. (© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)     

Novel Dithiolene Complexes and Tetrathiafulvalenes

Abstract

Novel dithiolene metal complexes, some of which absorb in the near infrared, and tetrathiafulvalenes, in particular tetraiodotetrathia- fulvalene, have been prepared, and their magnetic properties studied.     

Substrate Envelope-Designed Potent HIV-1 Protease Inhibitors to Avoid Drug Resistance

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