Application of spectroscopic imaging in epilepsy

Functional and anatomical neuroimaging has had a dramatic effect on the evaluation of patients for seizure surgery. The demonstration by PET that the epileptogenic focus has interictal metabolic abnormalities has allowed a greater number of patients to come to seizure surgery, with fewer of these patients requiring intracranial electrode evaluations. Metabolic changes have also been demonstrated utilizing single voxel and whole brain ¹H and ³¹P MRS imaging techniques with the interictal focus characterized by increased Pi, pH, and decreased PME and NAA. These findings can be used to accurately lateralize temporal lobe as well as frontal lobe epilepsy. Furthermore, there is evidence that these findings can be used to localize the seizure focus with the changes specific for the epileptogenic region; although, more diffuse changes both ipsilaterally and contralaterally have been seen. In patients with anterior hippocampal seizure foci the pH is significantly alkaline only in the ipsilateral hippocampus, whereas the increased Pi and decreased PME can be seen throughout the ipsilateral temporal lobe. When compared to controls the contralateral hemisphere is acidotic. Decreased NAA concentrations as well as NAA/Cr ratios have been demonstrated in the epileptogenic region in temporal and frontal lobe epilepsy. The decreased NAA has been correlated with the severity of cell loss, and may be a more sensitive measure than qualitative or quantitative measures of the hippocampal atrophy; however, the NAA decrease is more widespread than just the epileptogenic focus but may be maximal at the site of seizure initiation. In preliminary work, NAA maps of deviation from normality have suggested the maximal change to coincide with the epileptogenic region. These results suggest that in focal epilepsy there is abnormal metabolic activity throughout the brain detectable by MRS, with patterns of metabolic asymmetry that are useful for seizure localization.     

β-榄香烯振动光谱的量子化学从头计算

利用G98及GAMESS从头计算程序的RHF／6－31方法,对β－榄香烯的全部振动基频作了计算,并与实测红外光谱做了对比,归属了它们的振动模式,讨论了它们的特征基频,并对理论计算的振动频率进行了标度校正。     

Solution of Some Structural Analysis Problems by Orthogonal Collocation

Abstract

Application of the method of orthogonal collocation to boundary value problems in structural and applied mechanics is investigated. Typical boundary value problems, such as the torsion of rectangular bars and the bending of plates, are employed as illustrative examples. Simplicity in application and good accuracy of orthogonal collocation are demonstrated by the solution of such complex problems as the large deflection analysis of rectangular isotropic, orthotropic, and sandwich plates. Results are compared wherever possible with existing solutions based on much more laborious and lengthy methods of computation. Excellent agreements are obtained.     

A simple leading particle explanation for linear momentum transfer systematics

A simple formula based on leading particle models of nucleon-nucleon collisions is used to evaluate the average momentum transfer in central heavy ion collisions at energies from 20 to 150 MeV/u. This formula, which reproduces a number of the features of the observed systematics, offers a straightforward explanation for the approximate universality of fractional linear momentum transfer as a function of velocity, the dependence of fractional momentum transfer on target mass and the greater fractional momentum transfer of the proton as compared to heavy ion projectiles.     

Model for the evolution of hot and compressed spherical nuclei

A hydrodynamical approach and the Thomas Fermi approximation have been used to study the evolution of hot and compressed nuclei. Spherical symmetry was assumed in the calculation. The dynamical equations have been transformed into “Schrödinger like” equations (using the Madelung transformation) and were solved numerically. Dissipation was simulated in the same way as in the Navier-Stokes equation by introducing shear and bulk viscosities. Global as well as local thermal equilibrium have been studied. The model has been applied to small amplitude oscillations (the breathing mode) and to the stability of hot and compressed nuclei. It was found that compression is more efficient to break nuclei than thermal excitation. The relaxation time for global equilibrium was estimated to be of the order of 10^?22 s. It was found that the results obtained in the case of global and local thermal equilibrium are very similar.     

Anomalous magnetic moment of theW-bosons and non-standardZ 0 W + W − coupling in polarizede − e + collisions

We study quantitatively the reactions \(e^ + e^ - \to W^ + e\bar \nu _e \) ,e _R ^? e ⁺ and the rare decay \(Z^0 \to W^ \pm l^ \mp \mathop {\nu _e }\limits^{( - )} \) forl=e, μ and τ, as a test for anomalous γW ⁺ W ^? andZ ⁰ W ⁺ W ^? structure. If κ denotes the anomalous magnetic moment of theW-boson and ω its anomalous coupling to theZ ⁰, values of |ω|>2.5 and |κ|>1.5 can be ruled out at LEP and SLC rather easily. This will put constraints on composite model building.     

黑腔靶X光转换,输运的定量测量

为了测量黑腔靶X光引光效率、转换效率,我们设计了相应的分解靶(泄漏靶)实验,1989～1992年在″神光″装置上共进行了四次漏靶分解实验,利用灵敏度作了绝对标定的平响应X光二极管对漏靶注入孔、引光孔流出的X光角分布进行了测量,测出了x光角分布,得到了黑腔靶X光转换效率为50％～60％,引光效率约6％,为以后辐射驱动内爆研究的理论计算和靶的优化设计提供了重要的数据。