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91.
92.
Anamika Das Christoph Marschner Joan Cano Judith Baumgartner Joan Ribas M. Salah El Fallah Samiran Mitra 《Polyhedron》2009
Two new dicyanamido-bridged di- and polynuclear complexes of Co(II), [Co(dca)(tptz)(H2O)]2·2(ClO4) (1) and [Co(dca)2(imz)2]n (2) [dca, dicyanamide; tptz, 2,4,6-tris(2-pyridyl)1,3,5-triazine; and imz, imidazole] have been synthesized and characterized structurally, as well as magnetically. The X-ray single crystal structure determination of complex 1 shows that two symmetry related octahedral Co(II) ions are separated by dca ligand and other coordination sites are satisfied by tptz and aquo ligands. Each dinuclear unit is associated with each other by intramolecular hydrogen bonding interactions, giving rise to a 1D chain structure. On the other hand complex 2 is a 1D coordination polymer having [Co(II)(imz)2] units connected by double bridging dca ligands. These 1D chains interact through face-to-face π–π stacking interactions of the imz rings extending the dimensionality to a 2D supramolecular network. The variable temperature (300–2 K) magnetic measurements of both compounds reveal that dicyanamide exhibits a weak antiferromagnetic interaction between the metal centers. 相似文献
93.
Denise Huber Judith Rudolf Parisa Ansari Brigitte Galler Manuela Führer Christoph Hasenhindl Sabine Baumgartner 《Analytical and bioanalytical chemistry》2009,394(2):539-548
Blocking is an important step before an enzyme-linked immunosorbent assay (ELISA) can be performed. It reduces non-specific
binding to the microtiter plate to a minimum. For detecting food allergens by means of ELISA, the problem with protein blocking
solutions is obvious. The blocker might interfere with the antibodies of the assay and leads to false positive results. Therefore,
other blocking solutions are greatly needed. There are some alternatives like synthetic blockers or carbohydrates. Comparisons
of these different blocking agents, namely proteins, carbohydrates, and synthetic blockers, were made at different reaction
conditions. The incubation periods and temperatures were varied, as well as the pH. The best combinations were evaluated and
compared, in respect of their blocking efficiency. The two best non-proteinaceous blockers, i.e. polyvinylalcohol and Ficoll,
were subsequently applied to ELISA tests for the determination of α-casein and peanut. The study showed that Ficoll and PVA
did as well as BSA in buffer solution. Therefore, they can be considered as alternative blocking reagents for ELISA, especially
for the detection of food allergens. 相似文献
94.
Judith Cudaj 《Tetrahedron letters》2010,51(23):3092-3094
We present a total synthesis of the fungal natural product graphislactone G, a chlorinated resorcylic lactone. The key step is a Suzuki coupling used for the construction of the central biaryl bond. Graphislactone G was prepared in 13 steps with 22% yield starting with orcinol and phloroglucinic acid, where the longest linear sequence consists of nine steps. 相似文献
95.
F. J. Melendez Omar Urzúa M. Judith Percino Victor M. Chapela 《International journal of quantum chemistry》2010,110(4):838-849
Ab initio methods at the levels HF/cc‐pVDZ, HF/6‐31G(d,p), MP2/cc‐pVDZ, and MP2/6‐31G(d,p), as well as methods based on density functional theory (DFT) employing the hybrid functional B3LYP with the basis sets cc‐pVDZ and 6‐31G(d,p), have been applied to study the conformers of 2,6‐distyrylpyridine. Bond distances, bond angles, and dihedral angles have been calculated at the B3LYP level. The calculated values were in good agreement with those measured by X‐ray diffraction analysis of 2,6‐distyrylpyridine. The values calculated using the Hartree‐Fock method and second‐order perturbation theory (MP2) were inconsistent. The optimized lowest‐energy geometries were calculated from the reported X‐ray structural data by the B3LYP/cc‐pVDZ method. Three conformations, A, B, and C, were proposed for 2,6‐distyrylpyridine. Calculations at the three levels of theory indicated that conformation A was the most stable structure, with conformations C and B being higher in energy by 1.10 and 2.57 kcal/mol, respectively, using the same method and basis function. The same trend in the relative energies of the three possible conformations was observed at the two levels of theory and with the different basis sets employed. The reported X‐ray data were utilized to optimize total molecular energy of conformation A at the different calculation levels. The bond lengths, bond angles, and dihedral angles were then obtained from the optimized geometries by ab initio methods and by applying DFT using the two basis functions cc‐pVDZ and 6‐31G(d,p). The values were analyzed and compared. The calculated total energies, the relative energies of the molecular orbitals, the gap between them, and the dipole moment for each conformational structure proposed for 2,6‐distyrylpyridine are also reported. © 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2010 相似文献
96.
Judith Schlagnitweit Gerhard Zuckerstätter Norbert Müller 《Magnetic resonance in chemistry : MRC》2010,48(1):1-8
Standard phase cycled NMR pulse sequences were generalized such that for each individual step of the pulse phase cycle the free induction decay is stored separately without phase correction. This is in contrast to the usual practice, where pulse responses are phase shifted immediately (by applying a ‘receiver phase’) and co‐added as they are stored. The approach used here allows one to extract different types of NMR information, which are usually referred to as different ‘experiments’, from the same raw data set a posteriori by using complex linear combinations. Storing the free induction decays of individual phase cycle steps separately and using specific linear combinations of these data to obtain a particular type of information increase the overall efficiency of a given set of NMR experiments substantially, because all information can be derived from a single multiplexed data set. This ‘super‐experiment’ requires only as much time as the most complex of the derived specific experiments alone. The principle of this multipurpose approach was demonstrated by performing different multiple‐quantum filtered COSY experiments. It also becomes possible to generate linear combinations, which differ from the conventionally acquired spectra a posteriori. For example, we implemented diagonal peak reduction by using zero‐ and single‐quantum filtered COSY contributions without requiring additional experiment time. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
97.
Prof. Dr. Mateo Alajarin Dr. Raul‐Angel Orenes Prof. Dr. Judith A. K. Howard Dr. Elinor C. Spencer Prof. Dr. Jonathan W. Steed Dr. Aurelia Pastor 《Chemistry (Weinheim an der Bergstrasse, Germany)》2012,18(8):2389-2397
Tris(2‐ and 3‐ureidobenzyl)amines with Cs symmetry self‐assemble in solution forming mixtures of regioisomeric capsular aggregates, one of which is chiral and the other centrosymmetric. Under certain conditions, a predominance of the centrosymmetric regioisomer is found before equilibrium, that is, a mixture close to the statistical ratio of the two species is reached. In the solid state, there is a preference for the centrosymmetric capsules. Molecular models of both regioisomeric aggregates have been built and analyzed for comparison. Guests inside capsules formed by self‐assembly of desymmetrized tris(3‐ureidobenzyl)amines feel different magnetic environments, depending on whether they are inside a chiral or an achiral regioisomeric container. Of special significance are the experiments with a more flexible triurea endowed with an ureidopropylic arm, which self‐assembles with the same efficiency as the more rigid tris(ureidobenzyl)amines. 相似文献
98.
Dr. Raquel Andreu Dr. Santiago Franco Prof. Javier Garín Judith Romero Dr. Belén Villacampa Dr. María Jesús Blesa Dr. Jesús Orduna 《Chemphyschem》2012,13(13):3204-3209
Multichromophoric calix[4]arenes with two or four disperse red one (DR1) moieties linked to the lower rim have been synthesized. The second‐order nonlinear optical activity was measured by using the electric‐field‐induced second‐harmonic generation technique and there was a nearly linear increase of the μβ value with the number of chromophores in the molecule without affecting the charge‐transfer absorption wavelength. The effect that the number of DR1 units plays on the hyperpolarizability, the dipole moment, and the absorption maxima has been also studied by using quantum chemical calculations. It was found that it was necessary to synthesize multichromophores with distant chromophores to obtain large nonlinear optical responses. 相似文献
99.
Akutsu H Akutsu-Sato A Turner SS Le Pevelen D Day P Laukhin V Klehe AK Singleton J Tocher DA Probert MR Howard JA 《Journal of the American Chemical Society》2002,124(42):12430-12431
Normal state conductivity and superconductivity together with bulk magnetic susceptibility and magnetization measurements have been measured for two molecular charge-transfer salts: beta' '-(ET)4[(H3O)Ga(C2O4)3]G (ET = bis(ethylenedithio)tetrathiafulvalene, G = pyridine for compound I and nitrobenzene for compound II). With the exception of the included guest molecules (G) the crystal structures are almost identical. Both show minima in their electrical transport at 130 K for I and at 160 K for II, but at lower temperatures their behaviors differ markedly. The resistance of I reaches a maximum at 50 K with a further small peak at 2 K and possible superconductivity only below 2 K, whereas that of II increases continuously down to 7.5 K, where an abrupt transition to a superconducting state occurs. 相似文献
100.
Hao B Zhao G Kang PT Soares JA Ferguson TK Gallucci J Krzycki JA Chan MK 《Chemistry & biology》2004,11(9):1317-1324
L-pyrrolysine, the 22(nd) genetically encoded amino acid, was previously deduced to be (4R, 5R)-4-substituted-pyrroline-5-carboxylate attached to the epsilon-nitrogen of lysine based on the crystal structure of the M. barkeri monomethylamine methyltransferase (MtmB). To confirm L-pyrrolysine's identity, structures of MtmB have been determined following treatment with hydroxylamine, N-methylhydroxylamine, or dithionite. Analysis of these structures has provided additional support for the presence of the pyrroline ring and, together with previous mass spectroscopy data, has led us to assign the C(4)-substituent to a methyl group. Based on this assignment, synthetic L-pyrrolysine was prepared by chemical methods. Detailed study of this chemically synthesized L-pyrrolysine has allowed us to characterize its physical properties, to study its chemical stability, and to elucidate the role of its C(4) substituent. Future applications of this synthetic L-pyrrolysine include its in vivo incorporation into recombinant proteins. 相似文献