Syntheses,Crystal Structures and Bioactivities of Two Isatin Derivatives

The title compounds(Z)-3-(2-(3-chloropyridin-2-yl)hydrazono)indolin-2-one(A) and 7-bromo-(Z)-3-((4-pyridinyl)carboxlichydrazono)-2-indolinone(B) have been synthesized and structurally determined by elemental analysis and single-crystal X-ray diffraction studies.Compound A(C13H8ClN4O) belongs to the orthorhombic crystal system,space group Pca21 with a = 20.799(4),b = 4.9312(10),c = 11.764(2),V = 1206.6(4)3,Mr = 271.68,Dc = 1.496 g/cm3,μ = 0.313 mm-1,F(000) = 556,Z = 4,the final R = 0.0346 and wR = 0.0831 for 2683 observed reflections with I > 2σ(I).Compound B(C14H9BrN4O2) belongs to the triclinic crystal system,space group P1 with a = 6.6834(13),b = 7.0727(14),c = 14.285(3),α = 95.56(3),β = 99.00(3),γ = 102.95(3)°,V = 643.8(2)3,Mr = 345.16,Dc = 1.780 g/cm3,μ = 3.203 mm-1,F(000) = 344,Z = 2,the final R = 0.0487 and wR = 0.1167 for 2334 observed reflections with I > 2σ(I).The preliminary herbicidal bioassay reveals that compounds A and B have some inhibition both in vivo and in vitro against AHAS.     

Inhibition effects of protein-conjugated amorphous zinc sulfide nanoparticles on tumor cells growth

In this article, a facile and environmentally friendly method was applied to fabricate BSA-conjugated amorphous zinc sulfide (ZnS) nanoparticles using bovine serum albumin (BSA) as the matrix. Transmission electron microscopy analysis indicated that the stable and well-dispersed nanoparticles with the diameter of 15.9 ± 2.1 nm were successfully prepared. The energy dispersive X-ray, X-ray powder diffraction, Fourier transform infrared spectrograph, high resolution transmission electron microscope, and selected area electron diffraction measurements showed that the obtained nanoparticles had the amorphous structure and the coordination occurred between zinc sulfide surfaces and BSA in the nanoparticles. In addition, the inhibition effects of BSA-conjugated amorphous zinc sulfide nanoparticles on tumor cells growth were described in detail by cell viability analysis, optical and electron microscopy methods. The results showed that BSA-conjugated amorphous zinc sulfide nanoparticles could inhibit the metabolism and proliferation of human hepatocellular carcinoma cells, and the inhibition was dose dependent. The half maximal inhibitory concentration (IC50) was 0.36 mg/mL. Overall, this study suggested that BSA-conjugated amorphous zinc sulfide nanoparticles had the application potential as cytostatic agents and BSA in the nanoparticles could provide the modifiable site for the nanoparticles to improve their bioactivity or to endow them with the target function.     

Analysis of polarization dependence for OTDM demultiplexers based on four-wavelength mixing in semiconductor optical amplifier

In optical time-division multiplexing (OTDM) systems using the four-wave mixing (FWM) in a semiconductor optical amplifier (SOA) for time demultiplexing, the polarization states of control pulse and OTDM data lights are an important factor in the optical time demultiplexing process, which can influence the bit error rate (BER) of OTDM systems. In this paper, we analyze the effect of light polarization states on the FWM of a SOA, and use a simulation approach to study the BER performance of 100 Gbit/s OTDM systems that use the FWM in a SOA for optical time demultiplexing. It reveals that the BER or Q factor of OTDM systems is dependent on the misalignment θ between the polarization states of OTDM data and control lights. With increasing θ, both the optical power of resulting FWM component and the BER performance (or Q factor) of OTDM systems is degraded. For linearly polarized lights, our results show that the increase of BER and the reduction in Q factor are made smoothly when θ changes its value from 0° to 75°, whereas the degradation of BER and Q factor becomes rapid when θ exceeds 75°. Although the best system BER is obtained for θ = 0°, the BER performance can still tolerate some misalignment θ (e.g., up to 20° in our simulation). This is useful for the engineering design and applications of SOA-based optical time demultiplexers.     

自贡地区恐龙骨骼化石及围岩特征的研究

自贡地区恐龙化石埋藏丰富、分布广泛、保存完整,具有重要的科学价值、社会价值和经济价值。用X荧光衍射研究自贡恐龙骨骼化石及围岩元素组成,XRD结合红外光谱仪分析确定化石的矿物组成,化石切片和显微观察了解骨骼内部构造和填充物质。恐龙骨骼化石及围岩中的含钙量均较高(5%),但化石含钙量达到30%以上;化石中的含硅量较低(0.24%—1.45%),围岩中的含硅量较高(14%);化石中的含磷量为围岩的46倍以上。化石的主要化学成分是碳氟磷灰石,其次是碳酸钙;围岩的主要成分是二氧化硅。实验结果可为恐龙化石的鉴别及保护材料的研制提供理论依据。     

超声提取-反相高效液相色谱法测定黄姜中薯蓣皂甙元

以超声萃取-酸水解-超声萃取进行预处理,结合RP-HPLC测定黄姜中薯蓣皂甙元含量。色谱条件为:采用AglilengtHC-C18色谱柱,流动相为甲醇∶水=95∶5(V∶V),流速为1.0mL/min,UV检测波长为203nm。结果表明,在40—1000μg/mL范围内,薯蓣皂甙元峰面积与其质量浓度具有良好的线性关系(r=0.9996),样品平均加标回收率为99.8%,RSD为1.1%。与直接酸水解-萃取预处理方式进行对比,本方法测得薯蓣皂甙元含量提高了32%。采用本方法对黄姜芽,根茎,表皮及不定根中的薯蓣皂甙元含量进行测定:根茎1.69%,芽0.19%,表皮0.15%,不定根部分含量为0.36%。     

Collective Band Structures and Identification of One-Phonon and Two-Phonon γ-Vibrational Bands in 109Tc

The high spin states of the neutron-rich 109Tc nucleus are reinvestigated by observing prompt γ-rays from the spontaneous fission of 252 Cf. The previously known yrast band based on the 7/2＋ state is updated. A side band built on the 11/2＋ state is expanded and a new band based on the 15/2＋ state is identified. Band crossing in the yrast band occurs around fω≈ 0.36 MeV. This band crossing is associated with the alignment of two h11/2 neutrons according to the cranked shell model calculations. The band based on the 11/2＋ state is proposed as a candidate for the one-phonon γ-vibrational band, and the band built on the 15/2＋ state is proposed as a candidate for the two-phonon γ-vibrational band. Other characteristics for the observed bands are discussed.     

Zr-based bulk metallic glass with super-plasticity under uniaxial compression at room temperature

Commonly, bulk metallic glasses exhibit very limited plastic deformation (<2%) at room temperature. In this letter, through appropriate composition choices, rods of Zr_62.55Cu_17.55Ni_9.9Al₁₀ and Zr_64.80Cu_14.85Ni_10.35Al₁₀ bulk metallic glasses (BMGs) were prepared by using copper-mold suction-casting. X-ray diffraction and differential scanning calorimetry were utilized to determine their structures and thermal stabilities, and uniaxial compression tests were adopted to study their plastic deformation behaviors (PDBs) at room temperature. The results showed that T_g and T_x of the former are 651.5 K and 748 K, respectively, while those of the latter are 646 K and 750 K, respectively. Micro-hardness values are 693 ± 7 Hv and 595 ± 5 Hv for T1 and T2, respectively. During the compression tests, the former underwent about 2.5% engineering strain, i.e., 2.8% true strain, then fractured. While the latter was compressed into a flake-like form, of which, engineering strain values are larger than 70%, i.e., true strain exceeds 120%, showing super-plasticity at room temperature. It can be concluded that micro-hardness and PDBs of BMGs are very sensitive to composition.     

Multiple periodic-soliton solutions of the $$$$-dimensional generalised shallow water equation

Based on the extended variable-coefficient homogeneous balance method and two new ansätz functions, we construct auto-Bäcklund transformation and multiple periodic-soliton solutions of \((3\,{+}\,1)\)-dimensional generalised shallow water equations. Completely new periodic-soliton solutions including periodic cross-kink wave, periodic two-solitary wave and breather type of two-solitary wave are obtained. In addition, cross-kink three-soliton and cross-kink four-soliton solutions are derived. Furthermore, propagation characteristics and interactions of the obtained solutions are discussed and illustrated in figures.     

基于不分裂算法的Euler网格细分方法

 对考虑多物质相互作用的爆炸冲击数值模拟,Euler型流体动力学方法是最有效的方法之一。采用维数不分裂算法处理Euler坐标下的纯物质网格,混合网格在Youngs界面重构技术的基础上进行细分,消除混合网格复杂的输运计算。对纯物质网格和细分后网格,都具体给出了往相邻八个网格输运的所有可能分配量的表达式。最后将该方法加入到自行开发的MMIC-2D通用多物质二维爆炸与冲击问题数值仿真程序中,数值算例显示本文采用方法不仅能有效地提高计算精度,同时能降低问题的计算工作量,节省计算时间。