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71.
In the course of screening of angiogenesis inhibitor from natural products, cryptotanshinone from Salvia miltiorrhiza was isolated as a potent small molecule inhibitor of angiogenesis. Cryptotanshinone inhibits bFGF-induced angiogenesis of BAECs at ten micromolar ranges in vitro without cytotoxicity. Tanshinone IIA, another tanshinone isolated from S. miltiorrhiza, which is structurally very similar to cryptotanshinone except C-15 position of dihydrofuran ring does not inhibit angiogenesis induced by bFGF. These results demonstrate that cryptotanshinone is a new anti-angiogenic agent and double bond at C-15 position of the dihydrofuran ring plays a crucial role in the activity. 相似文献
72.
In this note, we study the action of finite groups of symplectic automorphisms on K3 surfaces which yield quotients birational
to generalized Kummer surfaces. For each possible group, we determine the Picard number of the K3 surface admitting such an
action and for singular K3 surfaces we show the uniqueness of the associated abelian surface.
Received: 9 April 1998 / Revised version: 17 July 1998 相似文献
73.
Sun-Ae Moon Tae-Gu Lee Jin-Huek Hur Ki-Moo Heo Hoseon Yoo Seung-Jae Moon Jae-Heon Lee 《Heat and Mass Transfer》2008,44(11):1345-1353
In this paper, the averaged reentering rates of the densely built cooling towers, which form banks on the building roof in
Seoul, Korea have been predicted by a numerical method according to various summer wind conditions and roof wall types. The
averaged reentering rates of all the cooling towers are compared according to two wall types to study the effect of the intake
outdoor air louver on the reentering rates. Consequently, two findings are drawn as follows. (1) With a curtain wall, the
averaged reentering rates of the total cooling towers against the west and the south wind at ν = 5 m/s are 13.3 and 24.4%, respectively. Therefore, it is strongly needed to find a method to reduce the reentering of the
discharged air from the cooling towers. (2) In the case of a louver wall, the averaged reentering rates of the cooling towers
with the west and south wind at ν = 5 m/s are 2.5 and 9.74%, respectively, which have been estimated to be lower than those of the curtain wall. Therefore,
the louver wall can be suitably adopted to reduce the reentering of the discharged air from the cooling towers in the present
study. 相似文献
74.
75.
We show that the Bose-Fermi Kondo model (BFKM), which may find applicability both to certain dissipative mesoscopic qubit devices and to heavy-fermion systems described by the Kondo lattice model, can be mapped exactly onto the Caldeira-Leggett model. This mapping requires an ohmic bosonic bath and an Ising-type coupling between the latter and the impurity spin. This allows us to conclude unambiguously that there is an emergent Kosterlitz-Thouless quantum phase transition in the BFKM with an ohmic bosonic bath. By applying a bosonic numerical renormalization group approach, we thoroughly probe physical quantities close to the quantum phase transition. 相似文献
76.
Background
Glioblastoma multiforme (GBM) is the most frequently encountered brain cancer. Although the existence of cancer stem cells in GBM has been previously established, there is little evidence to explain the difference between cancer stem cells and radio-resistant cells in GBM. In an effort to increase our understanding of whether cellular radio-resistance is a characteristic associated with cancer stem cells, we developed a dissociated cell system of subpopulations derived from GBM, and demonstrated radiotherapy resistance therein. 相似文献77.
Sharma PA Ahn JS Hur N Park S Kim SB Lee S Park JG Guha S Cheong SW 《Physical review letters》2004,93(17):177202
The thermal conductivity of the magnetically frustrated, ferroelectric YMnO3 exhibits an isotropic suppression in the cooperative paramagnetic state, followed by a sudden increase upon magnetic ordering. This unprecedented behavior without an associated static structural distortion probably originates from the strong dynamic coupling between acoustic phonons and low-energy spin fluctuations in geometrically frustrated magnets. The replacement of magnetic Ho for Y at the ferroelectrically active site results in an even larger effect, suggestive of the strong influence of multiferroicity. 相似文献
78.
Sharma PA Hur N Horibe Y Chen CH Kim BG Guha S Cieplak MZ Cheong SW 《Physical review letters》2002,89(16):167003
Our results from various transport experiments on Mg1-xB2 indicate a surprising effect associated with the presence of a Mg deficiency in MgB2: the phase separation between Mg-vacancy rich and Mg-vacancy poor phases. The Mg-vacancy poor phase is superconducting, but the insulating nature of the Mg-vacancy rich phase probably originates from the Anderson (disorder-induced) localization of itinerant carriers. Furthermore, electron diffraction measurements indicate that within vacancy-rich regions these defects tend to order with intriguing patterns. This electronic phase separation in Mg1-xB2 shows similar, but also distinct characteristics compared with that observed in La(2)CuO(4+delta). 相似文献
79.
We investigate the dynamical charge response of the Anderson model viewed as a quantum RC circuit. Applying a low-energy effective Fermi liquid theory, a generalized Korringa-Shiba formula is derived at zero temperature, and the charge relaxation resistance is expressed solely in terms of static susceptibilities which are accessible by Bethe ansatz. We identify a giant charge relaxation resistance at intermediate magnetic fields related to the destruction of the Kondo singlet. The scaling properties of this peak are computed analytically in the Kondo regime. We also show that the resistance peak fades away at the particle-hole symmetric point. 相似文献
80.