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81.
Ioana ?uvaina 《Annals of Global Analysis and Geometry》2012,41(1):109-123
Let
N0=\mathbb C2/H{N_0={\mathbb C}^2/H} be an isolated quotient singularity with H ì U(2){H\subset U(2)} a finite subgroup. We show that for any
\mathbb Q{\mathbb Q} -Gorenstein smoothings of N
0 a nearby fiber admits ALE Ricci-flat K?hler metrics in any K?hler class. Moreover, we generalize Kronheimer’s results on
hyperk?hler 4-manifolds (J Differ Geom 29(3):685–697, 1989), by giving an explicit classification of the ALE Ricci-flat K?hler surfaces. We construct ALF Ricci-flat K?hler metrics
on the above non-simply connected manifolds. These provide new examples of ALF Ricci-flat K?hler 4-manifolds, with cubic volume
growth and cyclic fundamental group at infinity. 相似文献
82.
It is proved that the solutions to the singular stochastic p-Laplace equation, p∈(1,2) and the solutions to the stochastic fast diffusion equation with nonlinearity parameter r∈(0,1) on a bounded open domain Λ⊂Rd with Dirichlet boundary conditions are continuous in mean, uniformly in time, with respect to the parameters p and r respectively (in the Hilbert spaces L2(Λ), H−1(Λ) respectively). The highly singular limit case p=1 is treated with the help of stochastic evolution variational inequalities, where P-a.s. convergence, uniformly in time, is established. 相似文献
83.
Gisle Atsang Kiki Raluca Maria Pop Octavia Sabin Ioana Corina Bocsan Veronica Sanda Chedea Sonia Ancua Socaci Alina Elena Prvu Egre Finsia Takvou Francis Zramah Mathieu Anca Dana Buzoianu 《Molecules (Basel, Switzerland)》2022,27(17)
Dichrostachys cinerea (L.) Wigth & Arn. (DC) is widely used in traditional medicine against several inflammatory diseases, especially rheumatoid arthritis, because of its antioxidant and anti-inflammatory effects. This study aimed to characterize the polyphenol-rich DC fruit extracts and investigate the analgesic, anti-inflammatory, and antioxidant effects in a rat inflammation model induced by complete Freund’s adjuvant (CFA). Water and ethanolic extracts were characterized using liquid chromatography coupled with mass spectrometry (LC-MS), Fourier-transform infrared (FTIR) spectroscopy, and gas chromatography coupled with mass spectrometry (GC-MS). The polyphenol-rich extracts were administered in three different concentrations for 30 days. Pain threshold, thermal hyperalgesia, edema, and serum biomarkers specific to inflammatory processes or oxidative stress were evaluated. Both extracts were rich in polyphenolic compounds, mainly flavan-3-ols, proanthocyanidins, and flavone glycosides, which had important in vitro antioxidant capacity. DC fruit extracts administration had the maximum antinociceptive and anti-inflammatory effects after one day since the CFA injection and showed promising results for long-term use as well. The measurement of pro-inflammatory cytokines, cortisol, and oxidative stress parameters showed that DC extracts significantly reduced these parameters, being dose and extract-type dependent. These results showed potential anti-inflammatory, analgesic, and antioxidative properties and revealed the necessity of using a standardized polyphenolic DC extract to avoid result variability. 相似文献
84.
Mihai Andrei Raluca Paula Vacaru Anca Coricovac Radu Ilinca Andreea Cristiana Didilescu Ioana Demetrescu 《Molecules (Basel, Switzerland)》2021,26(9)
Dental pulp vitality is a desideratum for preserving the health and functionality of the tooth. In certain clinical situations that lead to pulp exposure, bioactive agents are used in direct pulp-capping procedures to stimulate the dentin-pulp complex and activate reparative dentinogenesis. Hydraulic calcium-silicate cements, derived from Portland cement, can induce the formation of a new dentin bridge at the interface between the biomaterial and the dental pulp. Odontoblasts are molecularly activated, and, if necessary, undifferentiated stem cells in the dental pulp can differentiate into odontoblasts. An extensive review of literature was conducted on MedLine/PubMed database to evaluate the histological outcomes of direct pulp capping with hydraulic calcium-silicate cements performed on animal models. Overall, irrespective of their physico-chemical properties and the molecular mechanisms involved in pulp healing, the effects of cements on tertiary dentin formation and pulp vitality preservation were positive. Histological examinations showed different degrees of dental pulp inflammatory response and complete/incomplete dentin bridge formation during the pulp healing process at different follow-up periods. Calcium silicate materials have the ability to induce reparative dentinogenesis when applied over exposed pulps, with different behaviors, as related to the animal model used, pulpal inflammatory responses, and quality of dentin bridges. 相似文献
85.
Raluca Maria Pop Ioana Corina Bocsan Anca Dana Buzoianu Veronica Sanda Chedea Sonia Ancua Socaci Michela Pecoraro Ada Popolo 《Molecules (Basel, Switzerland)》2020,25(22)
Natural products black cumin—Nigella sativa (N. sativa) and wild garlic—Allium ursinum (AU) are known for their potential role in reducing cardiovascular risk factors, including antracycline chemotherapy. Therefore, this study investigates the effect of N. sativa and AU water and methanolic extracts in a cellular model of doxorubicin (doxo)-induced cardiotoxicity. The extracts were characterized using Ultraviolet-visible (UV-VIS) spectroscopy, Fourier-transform infrared (FT-IR) spectroscopy, Liquid Chromatography coupled with Mass Spectrometry (LC-MS) and Gas Chromatography coupled with Mass Spectrometry (GC-MS) techniques. Antioxidant activity was evaluated on H9c2 cells. Cytosolic and mitochondrial reactive oxygen species (ROS) release was evaluated using 2′,7′-dichlorofluorescin-diacetate (DHCF-DA) and mitochondria-targeted superoxide indicator (MitoSOX red), respectively. Mitochondrial membrane depolarization was evaluated by flow cytometry. LC-MS analysis identified 12 and 10 phenolic compounds in NSS and AU extracts, respectively, with flavonols as predominant compounds. FT-IR analysis identified the presence of carbohydrates, amino acids and lipids in both plants. GC-MS identified the sulfur compounds in the AU water extract. N. sativa seeds (NSS) methanolic extract had the highest antioxidant activity reducing both intracellular and mitochondrial ROS release. All extracts (excepting AU methanolic extract) preserved H9c2 cells viability. None of the investigated plants affected the mitochondrial membrane depolarization. N. sativa and AU are important sources of bioactive compounds with increased antioxidant activities, requiring different extraction solvents to obtain the pharmacological effects. 相似文献
86.
Beteringhe Adrian Baciu Ion Caproiu Miron T. Constantinescu Titus Balaban Alexandru T. 《平面色谱法杂志一现代薄层色谱法》2003,16(4):268-270
JPC – Journal of Planar Chromatography – Modern TLC - The Z (1b and 2b, respectively) and E diastereomers (1c and 2c, respectively) of the O-methyloximes of testosterone (1a) and... 相似文献
87.
Yu.Ts. Oganessian M. Hussonnois Ch. Brianôcon S.A. Karamian Z. Szeglowski D. Ledu R. Meunier M. Constantinescu J.B. Kim O. Constantinescu 《Hyperfine Interactions》1997,107(1-4):129-139
The 178m2Hf with its long-lived (T1/2=31 y), high-spin Iπ = 16+, isomeric state, is a challenge for new and exotic nuclear physics studies. The 178m2Hf isomer has been produced in microweight quantities using the 176Yb(α,2n) nuclear reaction, by irradiation with a high-intensity beam using the U-200 cyclotron in Dubna. Radiochemistry and
mass separation methods have been developed, with the aim to separate and purify the produced Hf material. Thin targets of
isomeric hafnium-178 on carbon backings have been prepared and used in experiments with neutron, proton and deuteron beams.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
88.
Hyperfine structure and isotope shifts in the 5d6s2 a2D3/2--5d6s(a3D)6p z4F5/2
° transition of Hf II
W.Z. Zhao F. Buchinger J.E. Crawford S. Fedrigo S. Gulick J.K.P. Lee O. Constantinescu M. Hussonnois J. Pinard 《Hyperfine Interactions》1997,108(4):483-495
The hyperfine structure and isotope shifts of the transition between the 5d6s2 a2D3/2 ground state and the 5d6s(a3D)6p z4F5/2
° excited state of singly ionized hafnium at \lambda=340 nm have been investigated by laser spectroscopy using a radio-frequency
quadrupole ion trap. The magnetic dipole coupling constant A and electric quadrupole coupling constant B of the two atomic
levels for both stable isotopes 177Hf and 179Hf are determined. The changes of mean square nuclear charge radii \delta[ r2] of the stable Hf isotopes and the radioactive isotope 172Hf (T1/2=1.87a) have been extracted from the data.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
89.
90.