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51.
Th. Arnd Kühne Sven Odén U. Pratolongo Th. Schloesing E. W. Hilgard G. Richter A. Atterberg J. König J. Hasenbäumer O. Kleine-Möllhof D. J. Hissink M. L. Plonski Ch. J. Moore W. H. Fry H. E. Middleton J. B. Rather O. Lemmermann L. Fresenius L. J. Gillespie L. E. Wise N. M. Comber Ch. Brioux E. A. Fisher Neuman O. Nolte 《Analytical and bioanalytical chemistry》1924,64(5-6):241-248
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Celestyn M. Brotek George M. Shopp Sharon L Ryan Patricia M. Gillespie Donna F. Kusewitt M. S. Rajagopalan Kenneth D. Ley Ronald D. Ley 《Photochemistry and photobiology》1992,56(3):287-295
LP-BM5 murine leukemia virus (MuLV) induces an immunodeficiency syndrome (MAIDS) in C57BL/6 mice which resembles immunological abnormalities observed in early stages of human AIDS. In our study, MAIDS virus-infected mice were exposed to low doses of ultraviolet radiation (UVR) before and after virus inoculation and compared with MAIDS-infected but not UVR-exposed mice. In all tested parameters (blood IgM levels; mitogenic responses to PHA, ConA, LPS and anti-mu; MLR; antigenic response to SRBC; enlargement and histopathologic changes of the spleen) we observed the same trend: changes due to MAIDS infection were more pronounced in the UVR-exposed group than in the unexposed group. Statistically significant differences between these two groups were seen for mitogenic responses at two different time points after virus inoculation. These results demonstrate that in vivo UVR exposure enhances the immunosuppressive effects of a retroviral infection. UVR exposure may affect the progression of AIDS in a similar manner. 相似文献
54.
J. L. Oscarson S. E. Gillespie J. J. Christensen R. M. Izatt P. R. Brown 《Journal of solution chemistry》1988,17(9):865-885
The aqueous reactions, {ie865-1}were studied as a function of ionic strength at 275, 300, and 320°C using a flow calorimetric technique. Log K, H and S values were determined from the fits of the calculated and experimental heats while Cp values were calculated from the variation of H values with temperature. The log K and H values for the first two reactions agree well with literature values at these temperatures. No previous results have been reported for the third reaction. The use of equations containing identical numbers of positive and identical numbers of negative charges on both sides of the equal sign (isocoulombic reaction principle) was applied to the log K values determined in this study. The resulting plots of log K for the isocoulombic reactions vs. I/T were approximately linear, which demonstrates that the Cp values for these reactions are approximately zero.Deceased 5 September 1987 相似文献
55.
Th. Arnd Kühne Sven Odén U. Pratolongo Th. Schloesing E. W. Hilgard G. Richter A. Atterberg J. König J. Hasenbäumer O. Kleine-Möllhof D. J. Hissink M. L. Plonski Ch. J. Moore W. H. Fry H. E. Middleton J. B. Rather O. Lemmermann L. Fresenius L. J. Gillespie L. E. Wise N. M. Comber Ch. Brioux E. A. Fisher Neuman und O. Nolte 《Fresenius' Journal of Analytical Chemistry》1924,64(5-6):241-248
Ohne Zusammenfassung 相似文献
56.
Yu X Munge B Patel V Jensen G Bhirde A Gong JD Kim SN Gillespie J Gutkind JS Papadimitrakopoulos F Rusling JF 《Journal of the American Chemical Society》2006,128(34):11199-11205
We describe herein the combination of electrochemical immunosensors using single-wall carbon nanotube (SWNT) forest platforms with multi-label secondary antibody-nanotube bioconjugates for highly sensitive detection of a cancer biomarker in serum and tissue lysates. Greatly amplified sensitivity was attained by using bioconjugates featuring horseradish peroxidase (HRP) labels and secondary antibodies (Ab(2)) linked to carbon nanotubes (CNT) at high HRP/Ab(2) ratio. This approach provided a detection limit of 4 pg mL(-)(1) (100 amol mL(-)(1)), for prostate specific antigen (PSA) in 10 microL of undiluted calf serum, a mass detection limit of 40 fg. Accurate detection of PSA in human serum samples was demonstrated by comparison to standard ELISA assays. PSA was quantitatively measured in prostate tissue samples for which PSA could not be differentiated by the gold standard immunohistochemical staining method. These easily fabricated SWNT immunosensors show excellent promise for clinical screening of cancer biomarkers and point-of-care diagnostics. 相似文献
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58.
Amanda S. Lim Sergey L. Lopatnikov Norman J. Wagner John W. Gillespie 《ournal of non Newtonian Fluid Mechanics》2010,165(19-20):1342-1350
The behavior of a concentrated, hard-sphere colloidal suspension is evaluated using the split Hopkinson pressure bar (SHPB) experimental technique. The composition of the suspension is measured using thermograviometric analysis before and after loading. This, combined with recorded pressure distributions, result in the conclusion that the suspension undergoes high rate squeezing flow. Experimental results demonstrate that the suspension exhibits shear thickening consistent with that observed in standard rotational rheometry. At sufficiently high stresses the suspension exhibits a second regime of shear thinning behavior that is consistent with elastohydrodynamic theory that incorporates the shear modulus of the particles themselves. Further increases in stress result in irreversible behavior, i.e., rather than fracturing or crushing, the particles form non-reversible agglomerates during testing. This fact is demonstrated through the use of dynamic light scattering and electron microscopy. This behavior occurs within a regime of viscous material response which is seen to occur at normal strain rates and stresses over 104 s?1 and 40 MPa, respectively. 相似文献
59.
A high yielding one-pot procedure for the generation of 2-substituted benzimidazoles directly from 2-nitroanilines by in situ reduction and cyclization using a microwave procedure is described. 相似文献
60.
Spin—orbit relaxation of I(52P)(ΔE = 0.94 eV) by benzene-d6, has been studied at 297 K, using time-resolved atomic resonance fluorescence. A large isotope effect is observed, kC6H6 = (4.6 ± 0.7) × 10?13 cm3 molecule?1 s?1, and kC6D6 = (9.9 ± 1.0) × 10?15 cm3 molecule?1 s?1, despite evidence that formation of a bound collision complex may contribute to the quenching mechanism. The roles of resonant energy transfer channels, Franck—Condon factors and the density of final states, in the quenching process, are discussed. 相似文献