Fluorescent Probe ABM and Estimation of Immune State in Patients with Different Pathologies (Review Article)

The fluorescent probe ABM (3-aminobenzanthrone derivative) one of the fluorescent probes synthesized in Riga Technical University proved to be an excellent, independent model for studying cell membranes. In our work we have investigated the possibility of using the fluorescent probe ABM for detection of immune state in patients with different pathologies. There is a strong correlation among all studied ABM spectral parameters, immunological characteristics, clinical and laboratory investigations of the all observed patients groups. The obtained results suggest that ABM spectral parameters in cell suspension reflect the alterations of the cellular mechanisms of immunity. Therefore fluorescent method could be used as preliminary screening test in immune diagnostics instead of more expensive, time consuming methods (subset detection, radioisotope method etc.) used as routine in clinics. Spectral parameters of ABM reflect a wide range of interrelated (interdependent) characteristics of cells (physico-chemical state and microviscosity of membrane, proliferating and lipid metabolic activity of cells, distribution of cells among subsets). The observed change of the studied parameters reflects alterations of the cellular mechanisms of immunity which is a main focus for its application as preliminary screening test in immune diagnostics. The fluorescence based method is sensitive, less expensive and time consuming, technically simple and convenient.     

A Diffusive Strategic Dynamics for Social Systems

We propose a model for the dynamics of a social system, which includes diffusive effects and a biased rule for spin-flips, reproducing the effect of strategic choices. This model is able to mimic some phenomena taking place during marketing or political campaigns. Using a cost function based on the Ising model defined on the typical quenched interaction environments for social systems (Erdös-Renyi graph, small-world and scale-free networks), we find, by numerical simulations, that a stable stationary state is reached, and we compare the final state to the one obtained with standard dynamics, by means of total magnetization and magnetic susceptibility. Our results show that the diffusive strategic dynamics features a critical interaction parameter strictly lower than the standard one. We discuss the relevance of our findings in social systems.     

Diversity oriented heterocyclizations of pyruvic acids,aldehydes and 5-amino-<Emphasis Type=Italic>N</Emphasis>-aryl-1<Emphasis Type=Italic>H</Emphasis>-pyrazole-4-carboxamides: catalytic and temperature control of chemoselectivity

Heterocyclization reactions of pyruvic acids, aromatic aldehydes and 5-amino-N-aryl-1H-pyrazole-4-carboxamides yielding four different types of final compounds are described. The reactions involving arylidenpyruvic acids lead with high degree of selectivity to either 4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acids or 5-[(2-oxo-2,5-dihydrofuran-3-yl)amino]-1H-pyrazoles, depending on the catalyst type or temperature regime. The interactions based on arylpyruvic acids can take place under kinetic or thermodynamic control producing 7-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-7-carboxylic acids or 3-hydroxy-1-(1H-pyrazol-5-yl)-1,5-dihydro-2H-pyrrol-2-ones, respectively.     

Optimization of a holographic memory setup using an LCD and a PVA-based photopolymer

Holographic data pages were stored in a polyvinyl alcohol (PVA)/acrylamide (AA) photopolymer. This material is formed of AA photopolymers which are considered interesting materials for recording holographic memories. A liquid crystal device was used to modify the object beam and store the data pages in the material. During the storage process, some parameters like exposure time, beam ratio and reading beam intensity were controlled to obtain high image quality after the reconstruction process. The bit error rate (BER) was calculated fitting the histograms of the images to determine what parameters improve the quality of the images.     

Carbon-nanotube-based saturable absorbers for near infrared solid state lasers

We demonstrate the passive mode-locking of a diode-pumped Nd⁺³:YAG (central wavelength: 1.32 μm; pulse duration: 50 ps; output energy: up to 70 μJ) laser using a polymer film containing single-wall carbon nanotubes. The mode-locking regime is stable at a pump repetition rate of up to 1 kHz. We also investigate the temporal evolution of the light-induced absorption change of the polymer film containing carbon nanotubes in the spectral range of 1.3–1.5 μm by femtosecond time-resolved pump-probe measurements. The measurements reveal that light-induced transmission exhibits fast and slow components that last 280 fs and more than 10 ps, respectively. The third-order susceptibility of the polymer film containing single wall carbon nanotubes is as high as 10⁻¹¹ esu.     

New far-infrared emissions and frequency measurements in hydrazine

By means of a new CO₂ laser we performed a new investigation of the far-infrared laser emission spectrum of hydrazine excited by the 10P(32) and 10R(8) CO₂ laser lines. We found seven new lines and measured the frequency of four of them; moreover we measured the frequencies of two more lines previously reported in the literature with only wavelength measurements. The frequencies of the far-infrared laser emissions have been measured by means of a frequency-synthesis chain based on new InP Schottky diodes. The detected signal was beat-note generated in a Schottky diode between the far-infrared radiation, the harmonics of a 72 GHz frequency reference and a rf signal. We also characterized all of the observed lines by their polarization relative to the pumping CO₂ laser, the optimum pressure and the offset relative to the CO₂ center frequency. PACS 42.55.Lt; 42.62.Fi     

Energy and momentum losses in the process of neutrino scattering on plasma electrons in the presence of a magnetic field

The neutrino-electron scattering in a dense degenerate magnetized plasma under the conditions μ ² > 2eB ≫ μE is investigated. The volume density of the neutrino energy and momentum losses due to this process are calculated. The results we have obtained demonstrate that plasma in the presence of an external magnetic field is more transparent for neutrino than for non-magnetized plasma. It is shown that neutrino scattering under conditions considered does not lead to the neutrino force acting on plasma.     

Heavy charged Higgs boson production at next generation $\gamma\gamma$ colliders

We investigate the scope of all relevant production modes of charged Higgs bosons in the MSSM, with mass larger than the one of the top quark, at future Linear Colliders operating in mode at the TeV energy scale. Final states with one or two bosons are considered, as produced by both tree- and loop-level interactions. Received: 8 November 2002 / Revised version: 12 February 2003 / Published online: 13 May 2003 RID="a" ID="a" e-mail: stefano.moretti@cern.ch RID="b" ID="b" e-mail: kanemu@post.kek.jp     

Optoacoustic Laser Stark spectroscopy and FIR laser action on CH3Br using a waveguide CO2 laser

The optoacoustic spectrum of CH₃Br around 10 m band lines of a tunable cw waveguide CO₂ laser is investigated. Several new infrared absorptions are observed and most of the correspond ing molecular transitions are assigned. Far infra red laser action is reported by pumping with the same CO₂ laser: pump offsets are given using the Transferred Lambs dip (TLD) technique. A new FIR laser emission is obtained and assigned. An optoacoustic Laser Stark spectroscopy technique is used to investigate off resonance infrared tran sitions.