Thermal degradation behavior of some ruthenium complexes with fluoroquinolone derivatives as potential antitumor agents

Three new complexes with ligands belong to the fluoroquinolone class having the general formula [RuL₂Cl₂]Cl nH₂O ((1) L: norfloxacin (nf), n = 4; (2) L: ciprofloxacin (cp), n = 3; (3) L: enrofloxacin (enro), n = 5) were synthesized and characterized by chemical analysis UV–Vis and IR spectroscopy. In all complexes fluoroquinolone derivative acts as bidentate chelate ligand. The thermal behavior steps were investigated in synthetic air flow. The thermal transformations are complex processes according to TG and DTG curves including dehydration, quinolone derivative degradation, as well as RuCl₃ conversion in RuO₂.     

Testing Monotonicity

at arguments of its choice, the test always accepts a monotone f, and rejects f with high probability if it is ε-far from being monotone (i.e., every monotone function differs from f on more than an ε fraction of the domain). The complexity of the test is O(n/ε). The analysis of our algorithm relates two natural combinatorial quantities that can be measured with respect to a Boolean function; one being global to the function and the other being local to it. A key ingredient is the use of a switching (or sorting) operator on functions. Received March 29, 1999     

Long range correlation of hydrophilicity and flexibility along the calcium binding protein chains

Long range correlation concerning hydrophilicity and flexibility along a number of 80 calcium binding protein sequences is confirmed by using spectral analysis and detrended fluctuations analysis methods, as well as by Hurst exponent calculations. There are no significant differences between the correlation properties concerning these properties for the two structural subfamilies, extended and compact, of the calcium binding proteins and they are also similar with the correlation properties revealed by other investigated proteins. This result sustains the hypothesis that the long range correlation of hydrophilicity and flexibility along the chain is a common feature of proteins.     

Tris[2‐(morpholin‐4‐ylmethyl)phenyl‐κ2C1,N]antimony(III)

The title compound, [Sb(C₁₁H₁₄NO)₃], is monomeric with the Sb atom located on a threefold axis. The complex exhibits distorted trigonal–antiprismatic geometry around the Sb atom, owing to the presence of intramolecular N→Sb interactions. H...phenyl intermolecular interactions lead to the formation of dimers stacked along the c axis. The morpholine rings exhibit almost ideal chair conformations. No intermolecular interactions between the morpholine rings of neighbouring molecules were observed.     

Blends of a chlorinated poly(vinyl chloride) with a polyurethane

Blends of a 67% chlorinated poly(vinyl chloride) with a low-molecular-weight polyurethane are partially miscible over the 0–80% urethane compositional range. A single, composition-dependent glass transition temperature is observed from both DSC and dynamic mechanical measurements. The blends exhibit a cocontinuous morphology with domain sizes varying from 0.15 to 1.5 μm. These results point out that the relation between miscibility characteristics and domain size is a complex one, not only dependent upon the degree of miscibility, but also on the nature of the blend components and the test method used. Thus the domain size for a certain degree of miscibility is not a universal constant as was previously believed. The melt rheology of the blends as a function of composition is strongly “positive deviating” from the log additivity rule and fits a simplified version of the McAllister model. The strongly “positive deviating” rheological behavior of the blends is most likely a result of the cocontinuous morphology which makes the system behave as a highly entangled network.     

Monadic <Emphasis Type="Italic">GMV</Emphasis>-algebras

Monadic MV-algebras are an algebraic model of the predicate calculus of the Łukasiewicz infinite valued logic in which only a single individual variable occurs. GMV-algebras are a non-commutative generalization of MV-algebras and are an algebraic counterpart of the non-commutative Łukasiewicz infinite valued logic. We introduce monadic GMV-algebras and describe their connections to certain couples of GMV-algebras and to left adjoint mappings of canonical embeddings of GMV-algebras. Furthermore, functional MGMV-algebras are studied and polyadic GMV-algebras are introduced and discussed. The first author was supported by the Council of Czech Government, MSM 6198959214.     

Silica-based monolithic capillary columns—Effect of preparation temperature on separation efficiency

The temperature effects during the sol–gel process and ageing of the silica-based monolith on the structure and separation efficiency of the capillary columns (100 μm i.d., 150 mm) for HPLC separations were studied. The tested columns were synthesized from a mixture of tetramethoxysilane, polyethylene glycol and urea under the acidic conditions. The temperature was varied from 40 °C to 44 °C and formation of bypass channels between the silica mold and the capillary wall was examined. The temperature of 43 °C was estimated as optimal for preparation of efficient silica capillary columns which were subsequently modified by octadecyldimethyl-N,N-diethylaminosilane or covered by poly(octadecyl methacrylate) and tested using standard mixture of alkylbenzenes under the isocratic conditions.     

Engineering generalized synchronization in chaotic oscillators

We report a method of engineering generalized synchronization (GS) in chaotic oscillators using an open-plus-closed-loop coupling strategy. The coupling is defined in terms of a transformation matrix that maps a chaotic driver onto a response oscillator where the elements of the matrix can be arbitrarily chosen, and thereby allows a precise control of the GS state. We elaborate the scheme with several examples of transformation matrices. The elements of the transformation matrix are chosen as constants, time varying function, state variables of the driver, and state variables of another chaotic oscillator. Numerical results of GS in mismatched Ro?ssler oscillators as well as nonidentical oscillators such as Ro?ssler and Chen oscillators are presented.     

The spontaneous formation of inhomogeneity in a classical one-particle “gas”: An example in silico

A single classical isoergic particle was placed in a cube and allowed to propagate for 100 ns to 10 ms. The interaction of the particle with the inner wall of the cube was modeled as a linear combination of specular and random reflection, the extent of the combination being governed by a user-defined “roughness” parameter α. As a function of α, the particle’s relative pressure and density spontaneously took on an inhomogenous distribution.