全文获取类型
收费全文 | 1081篇 |
免费 | 22篇 |
国内免费 | 5篇 |
专业分类
化学 | 731篇 |
晶体学 | 6篇 |
力学 | 25篇 |
数学 | 167篇 |
物理学 | 179篇 |
出版年
2022年 | 14篇 |
2021年 | 27篇 |
2020年 | 27篇 |
2019年 | 19篇 |
2018年 | 24篇 |
2017年 | 15篇 |
2016年 | 32篇 |
2015年 | 23篇 |
2014年 | 49篇 |
2013年 | 87篇 |
2012年 | 69篇 |
2011年 | 82篇 |
2010年 | 43篇 |
2009年 | 58篇 |
2008年 | 68篇 |
2007年 | 50篇 |
2006年 | 57篇 |
2005年 | 58篇 |
2004年 | 41篇 |
2003年 | 35篇 |
2002年 | 30篇 |
2001年 | 14篇 |
2000年 | 13篇 |
1999年 | 17篇 |
1998年 | 10篇 |
1997年 | 9篇 |
1996年 | 17篇 |
1995年 | 7篇 |
1994年 | 15篇 |
1993年 | 5篇 |
1992年 | 3篇 |
1991年 | 3篇 |
1990年 | 5篇 |
1989年 | 9篇 |
1987年 | 5篇 |
1986年 | 6篇 |
1985年 | 8篇 |
1984年 | 4篇 |
1983年 | 2篇 |
1982年 | 3篇 |
1981年 | 5篇 |
1980年 | 6篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1974年 | 2篇 |
1973年 | 3篇 |
1968年 | 2篇 |
1967年 | 2篇 |
排序方式: 共有1108条查询结果,搜索用时 15 毫秒
951.
Edward J. Miracco Bogdan Bogdanov Eugene G. Mueller 《Rapid communications in mass spectrometry : RCM》2011,25(18):2627-2632
As part of the investigation of the pseudouridine synthases, 5‐fluorouridine in RNA was employed as a mechanistic probe. The hydrated, rearranged product of 5‐fluorouridine was isolated as part of a dinucleotide and found to undergo unusual fragmentation during mass spectrometry, with the facile loss of HNCO from the product pyrimidine ring favored over phosphodiester bond rupture. Although the loss of HNCO from uridine and pseudouridine is well established, the pericyclic process leading to their fragmentation cannot operate with the saturated pyrimidine ring in the product of 5‐fluorouridine. Based on the MSn results and calculations reported here, a new mechanism relying on the peculiar disposition of the functional groups of the product pyrimidine ring is proposed to account for the unusually facile fragmentation. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
952.
953.
954.
955.
A reliable protocol for the synthesis of a series of 8-amino analogues of pharmacologically interesting nitroxoline (5-nitro-8-hydroxyquinoline) is described. The unprecedented displacement of the cyanomethoxy group of an O-cyanomethylated quinoline derivative by various primary and secondary amines selectively affords 5-nitroquinolin-8-ylamines in moderate-to-high yields. The reactions were accelerated significantly under microwave conditions in comparison with conventional heating. 相似文献
956.
957.
958.
Oleksiy V. Grygorovych Sofia M. Moskalenko Bogdan A. Marekha Andrey O. Doroshenko 《Journal of fluorescence》2010,20(1):115-124
The new sensing materials based on the microsized silica gel powder with non-covalently immobilized structurally rigid analogs
of 2,6-distyrylpyrydine ((3E,5E)-3,5-dibenzylidene-8-phenyl-1,2,3,5,6,7-hexahydrodicyclopenta[b,e]pyridines) were developed and tested. Most of the investigated compositions demonstrate linear ratiometric fluorescence response
on pH in the physiologically important interval (pH 6–9). The compound with the greatest number of protolytic centers within the studied series demonstrated the widest pH sensitivity range, however in this case the analytical signal was the lowest. The prospects for the practical application
of the investigated materials in the fiber optics sensing devices were outlined. 相似文献
959.