全文获取类型
收费全文 | 681篇 |
免费 | 6篇 |
国内免费 | 6篇 |
专业分类
化学 | 378篇 |
晶体学 | 5篇 |
力学 | 18篇 |
数学 | 148篇 |
物理学 | 144篇 |
出版年
2020年 | 5篇 |
2019年 | 10篇 |
2018年 | 7篇 |
2017年 | 7篇 |
2016年 | 9篇 |
2015年 | 7篇 |
2014年 | 11篇 |
2013年 | 41篇 |
2012年 | 34篇 |
2011年 | 30篇 |
2010年 | 13篇 |
2009年 | 21篇 |
2008年 | 23篇 |
2007年 | 34篇 |
2006年 | 28篇 |
2005年 | 12篇 |
2004年 | 22篇 |
2003年 | 22篇 |
2002年 | 15篇 |
2001年 | 19篇 |
2000年 | 21篇 |
1999年 | 15篇 |
1998年 | 12篇 |
1997年 | 10篇 |
1996年 | 5篇 |
1995年 | 11篇 |
1994年 | 13篇 |
1993年 | 10篇 |
1992年 | 9篇 |
1990年 | 9篇 |
1989年 | 6篇 |
1988年 | 8篇 |
1987年 | 5篇 |
1985年 | 13篇 |
1984年 | 14篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1981年 | 11篇 |
1980年 | 8篇 |
1979年 | 11篇 |
1978年 | 13篇 |
1977年 | 13篇 |
1975年 | 8篇 |
1974年 | 5篇 |
1973年 | 9篇 |
1972年 | 5篇 |
1971年 | 5篇 |
1970年 | 7篇 |
1969年 | 9篇 |
1966年 | 5篇 |
排序方式: 共有693条查询结果,搜索用时 46 毫秒
11.
12.
Let (A) be the coefficient of the second term in the Laurentexpansion about T 1 of the Poincare series p(A, t) of a gradedring A. For a finite extension of integrally closed domains,we prove a formula relating if (B), if (A) and the differentialexponent of B over A. As an application, we prove a conjectureof Carlisle and Kropholler which computes for rings of modularinvariants of finite groups in terms of stabilizers of hyperplanes. 相似文献
13.
14.
Alverson G Baker WF Ballocchi G Benson R Berg D Blusk S Bromberg C Brown D Carey D Chand T Chandlee C Choudhary BC Chung WH de Barbaro L DeSoi W Dlugosz W Dunlea J Easo S Engels E Faissler W Fanourakis G Ferbel T Garelick D Ginther G Glass G Glaubman M Gutierrez P Hartman K Huston J Johnstone C Kapoor V Kourbanis L Lanaro A Lirakis C Lobkowicz F Lukens P Mani S Maul A Mansour J Miller R Nelson CA Oh BY Orris D Pothier E Prebys E Rajaram BM Roser R Ruddick K Shepard P Shivpuri RK Sinanidis A 《Physical review D: Particles and fields》1993,48(1):5-28
15.
Microcalorimetric measurements of excess molar enthalpies, at 298.15 K, are reported for the two ternary systems formed by mixing either diisopropyl ether or 2-methyltetrahydrofuran with binary mixtures of cyclohexane and n-heptane. Smooth representations of the results are presented and used to construct constant excess molar enthalpy contours on Roozeboom diagrams. It is shown that useful estimates of the ternary enthalpies can be obtained from the Liebermann and Fried model, using only the physical properties of the components and their binary mixtures. 相似文献
16.
Metalloprotein tethered CdSe nanoparticles have been generated to provide selective and reagentless maltose biosensing. As opposed to cell or protein detection by semiconducting nanoparticle bioconjugates, a modular method for small-molecule detection using semiconducting nanoparticle bioconjugates has been difficult. Here we report a method for reagentless protein-based semiconducting nanoparticle biosensors. This method uses Ru(II) complex-CdSe nanoparticle interactions and the maltose-induced conformation changes of maltose binding protein to alter the CdSe nanoparticle fluorescence emission intensity. In this proof-of-principle system, the maltose-induced protein conformation changes alter the Ru(II) complex-CdSe nanoparticle interaction, which increases the CdSe emission intensity. Altered CdSe emission intensity effects are best described as electron transfer from the Ru(II) complex to the CdSe excited state forming the nonfluorescent CdSe anion. Four surface-cysteine, Ru(II) complex-attached maltose-binding proteins have been studied for maltose dependent alteration of CdSe emission intensities. With 3.0-3.5 nm diameter CdSe nanoparticles, all ruthenated maltose-binding proteins display similar maltose-dependent increases (1.4-fold) in CdSe emission intensity and maltose binding affinities (KA = 3 x 106 M-1). For these four systems, the only difference was the sample-to-sample variation in maltose-dependent responses. Thus, very few surface cysteine mutations need to be examined to find a successful biosensor, as opposed to analogous systems using organic fluorophores. This strategy generates a unimolecular, or reagentless, semiconducting nanoparticle biosensor for maltose, which could be applied to other proteins with ligand-dependent conformation changes. 相似文献
17.
Volumetric heat capacities of the six binary mixtures formed from cyclopentane, cyclohexane, cycloheptane and cyclooctane were determined at 298.15 K in a Picker flow microcalorimeter. Excess heat capacities obtained from the results are compred with the temperature variation of excess enthalpies from the literature. 相似文献
18.
Brian A. Naughton Benson Sibanda Jory P. Weintraub Julia San Román Vafa Kamali 《Applied biochemistry and biotechnology》1995,54(1-3):65-91
A method of coculturing adult rat hepatic parenchymal cells (PC) and stromal cells in a three-dimensional framework of nylon
filtration screens or biodegradable polymer meshes was developed in our laboratory. Rat liver stroma, which includes vascular
and bile duct endothelial cells, fat-storing cells, fibroblasts, and Kupffer cells, were isolated by gradient centrifugation
afterin situ liver perfusion and expanded in monolayer culture prior to seeding onto nylon screens or bioresorbable polyglycolic acid
(PGA) polymers oriented into a felt-like construct. A second inoculum of freshly isolated PC was applied after the stromal
cells became established. Histological analyses revealed that PC proliferation occurred until all available space for expansion
within the template was exhausted. These cells retained their rounded morphology, and after 4–5 wk 7–9 “layers” of PC filled
the 140-μm deep template. Dioxin-inducible cytochrome P450 activity was detected for up to 58 d in culture, and albumin, fibrinogen,
transferrin, and soluble fibronectin were detected in the medium by enzyme-linked immunosorbent assay (ELISA) for 48 d in
vitro. Immunohistochemical analysis of sections through the cultures confirmed the presence of these proteins as well as cytokeratin
at the cellular level; the extracellular matrix stained for both collagen type III and laminin. Long-term PC proliferation
and function were enhanced by the presence of stromal cells as well as by a meshwork template whose geometry allows the interaction
of PC with stroma and matrix on several different planes. To permit transplantation, co-cultures of hepatic PC and stromal
cells were established on PGA felt constructs instead of nylon screens. After 24 d in vitro, these constructs were grafted
into sites in the mesentery, omentum, and sub-cutaneous tissues of adult Long-Evans rats. The growth of hepatocytes after
30 din situ was evident by histological analysis; grafts of co-cultures regenerated a liver-like architecture consisting of sinusoids
and putative biliary structures. In addition, PC at these extrahepatic graft sites were positive for albumin, transferrin,
and fibrinogen synthesis by immunohistochemistry. Graft survival was enhanced when recipients were subjected to 40% hepatectomy.
Hepatic PC:stromal cell cocultures may prove useful in the restoration of liver function either by direct transplantation
using PGA or similar templates, or as extracorporeal devices, using nylon screens. 相似文献
19.
MacLean EJ Harris KD Kariuki BM Kitchin SJ Tykwinski RR Swainson IP Dunitz JD 《Journal of the American Chemical Society》2003,125(47):14449-14451
The transformation of ammonium cyanate into urea, first studied over 170 years ago by W?hler and Liebig, has an important place in the history of chemistry. To understand the nature of this solid state reaction, knowledge of the crystal structure of ammonium cyanate is a prerequisite. Employing neutron powder diffraction, we demonstrate conclusively that, in the structure of ammonium cyanate, the NH(4)(+) cation forms N-H...N hydrogen bonds to four cyanate N atoms at alternate corners of a distorted cube, rather than our previously proposed alternative arrangement with N-H...O hydrogen bonds to cyanate O atoms at the other four corners. 相似文献
20.