CHEMICAL DERIVATION OF HUMAN INSULIN SUPERAGONISM

The role of three highly conserved insulin residues Tyr^B26 was studied to better understand the relationship between insulin and receptor from rat adipose tissue plasma membranes, lnsulin analogues with a single amino acid substitution or single N-methylation of the peptide bond in the position B26 were all shortened in the C-terminus of the B-chain by four amino acids. The effect of modifications was followed by the binding to the insulin receptor. From our results, we can deduce several conclusions： （1） the replacement of tyrosine in the position B26 by histidine, [N-MeHis^B26]-des-tetrapeptide-（B27-B30）-insulin-B26-amide and [N-MeGlu^B26]-des-tetrapeptide- （B2-B30）-insulin-B26-amide, have no significant effect on the binding affinity and they show binding affinity 105%, 190% and 208%, respectively, of that of human insulin; （2） [Aad^B26] -des-tetrapeptide-（B27-B30）-insulin-B26-amide and [Phe（4-carboxy^B26）]-des-tetrapeptide- （B27~B30）-insulin-B26-amide affect the potency highly positively in vitro studies; they show binding affinity 529 and 289 %, respectively, of that of human insulin.     

Fabrication of Hollow Materials by Fast Pyrolysis of Cellulose Composite Fibers with Heterogeneous Structures

A facile method for the fabrication of inorganic hollow materials from cuprammonium cellulose composite filaments based on fast pyrolysis has been developed. Unlike Ostwald ripening, approaches based on the Kirkendall effect, and other template methods, this process yielded hollow materials within 100 s. The heterogeneous structure of the cellulose composite fibers and the gradient distribution of the metal oxides are the main reasons for the formation of the hollow structure. The diameter, wall thickness, and length of the hollow microfibers could be conveniently controlled. With their perfect morphology, these hollow structural materials have great potential for use in various fields.     

聚环氧氯丙烷聚氨酯／聚甲基丙烯酸甲酯互穿网络聚合物的相容性与力学性能

用同步法合成了聚环氧氯丙烷聚氨酯／聚甲基丙烯酸甲酯互穿网络聚合物［ＰＵ（ＰＥＣＨ）／ＰＭＭＡＩＰＮ］，调节ＩＰＮ中两组分组成比制备出由完全弹性体、增强弹性体、增韧塑料到脆性塑料多种高聚物合金材料．用ＤＳＣ、动态力学谱、ＴＥＭ对ＩＰＮ的研究结果表明，ＰＵ（ＰＥＣＨ）／ＰＭＭＡＩＰＮ的两组分是完全相容的；同时对各种组成比的ＩＰＮ材料进行力学性能测试，用相容性ＩＰＮ中互穿、缠结结构解释其力学行为，并用ＳＥＭ对断面形貌进行了观察解释．     

聚醚醚酮酮（PEEKK）和含联苯结构聚醚醚酮酮（PEBEKK）共聚物的SAXS研究

应用一维电子密度相关函数方法，对含不同联苯结构的ＰＥＥＫＫ－ＰＥＢＥＫＫ共聚物样品小角Ｘ射线散射（ＳＡＸＳ）去模糊强度分析计算表明：ＰＥＥＫＫ－ＰＥＢＥＫＫ共聚物的聚集态结构明显地依赖于共聚物中联苯含量。当联苯含量ｎｂ＝０．３５时，积分不变量Ｑ，长周期Ｌ，平均结晶片层厚ｄ，电子密度差η_ｃ－η_ａ和结晶度Ｗ_（ｃ，ｘ）值为最小，比表面积Ｏ_ｓ为最大。     

Diode-pumped CW Tm:GdVO4 laser at 1.9 μm

A high power cryogenic cooling Tm-doped (2%) GdVO4 laser double-end-pumped by fiber-coupled-diode with the center wavelength of 804.5 nm at 21 ℃ is reported. The highest continuous-wave (CW) power of 2.35 W at 1903 nm is attained at pump power of 24 W. The slope efficiency is 12.5% and the threshold is 3.2 W. Single- and double-end-pumped types are investigated.     

Internal Optical Parametric Oscillator with SBS Phase Conjugate Resonator

It is reported a novel optical parametric oscillator with KTP as medium crystal inside a Nd∶YAG phase conjugate resonator. In the phase conjugate resonator, the laser beam quality is promoted by phase-conjugate mirror, which is realized by stimulated Brillouin scattering effect, and Q-switch is generated simultaneously. With this device, the laser output at 1.57 μm with 15 mJ energy and 8 ns pulse width is obtained.     

Self-assembly of gold nanoparticles into nanoholes through annealing in the fabrication of square lattices of nanocylinders

We demonstrate the self-assembly of solution-processible gold nanoparticles into the nanoholes consisting of patterned substrate through annealing, which facilitates successful fabrication of square lattices of gold nanocylinders with a period of 350 nm, a height of about 200 nm, and an aspect ratio larger than 2.     

受激布里渊散射相位共轭光泵浦的高效率光学参量振荡器

报道了在Ｎｄ：ＹＡＧ１．０６μｍ激光器上，用受激布里渊散射（ＳＢＳ）后向放大输出作泵浦光源，用光学参量振荡（ＯＰＯ）的方法，获得１．５７μｍ激光输出，最大输出能量为２１．６ｍＪ，相应的转换效率为３２％，并与直接用Ｎｄ：ＹＡＧ１．０６μｍ激光泵浦结果相比较，效率提高１．９倍，阈值降低１．７倍，实验结果与理论分析符合的较好。     

Wavelength pre-assignment collision schedule for wavelength-routed optical networks

A novel wavelength assignment scheme called the wavelength pre-assignment collision schedule （WPCS） is proposed for wavelength-routed networks. The WPCS pre-assigns the wavelength at the forward detection phase, and schedules the potential collision by priority. The potential collision is scheduled at the forward detection phase and the blocking of the wavelength assignment is reduced. Simulation is conducted with several other existing schemes. The numerical results show that WPCS performs better than other schemes in blocking probability under various traffic conditions.     

High efficient diode-pumped Tm:YAP laser at room temperature

A high efficient diode-pumped Tm:YAP laser is reported. The maximum output power at 1981 nm is 5.2 W and the slope efficiency is 30%. Unpolarized absorption near 800 nm and unpolarized fluorescence spectra near 1800 nm pumped by laser diode (LD) are measured. In addition, the relationship between operation temperature and output power is discussed.