ATML测试资源与测试需求自动匹配方法研究

基于ATML测试描述文档自动生成测试程序过程中,关键是实现测试资源与测试需求的自动匹配。首先对ATML测试描述文档中测试能力、测试需求、开关、端口、能力与资源的映射等基本数据元素的表示方法进行分析研究,定义了与其对应的C 数据类型。然后在研究图论相关理论的基础上,分析了描述文档中测试路径的表示方法,确定了采用邻接矩阵表示测试路径的方法。最后,在以上研究的基础上,提出了以稀疏矩阵和单链表为基础的测试能力与测试需求匹配算法,实现了测试能力与测试需求的自动匹配。该算法在实际测试程序开发中得到了应用,结果表明该算法能够实现基于ATML描述文档的测试资源与测试需求自动匹配,并能极大提供测试程序开发效率。     

Asymmetric Hydrophosphinylation of Alkynes: Facile Access to Axially Chiral Styrene-Phosphines

A Cu/CPA co-catalytic system has been developed for achieving the direct hydrophosphinylation of alkynes with phosphine oxides in delivering novel axially chiral phosphorus-containing alkenes in high yields and excellent enantioselectivities (up to 99 % yield and 99 % ee). DFT calculations were performed to elucidate the reaction pathway and the origin of enantiocontrol. This streamlined and modular methodology establishes a new platform for the design and application of new axially chiral styrene-phosphine ligands.     

Ullmann diaryl ether synthesis catalyzed by copper (I)/pyridine-functionalized silane

Ullmann-type diaryl ether synthesis was performed under mild conditions in DMF/K₂CO₃ using a pyridine-functionalized silane as a ligand. The products were obtained in good yields. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl ethers.     

On the tautological ring of a Jacobian modulo rational equivalence

We consider the Chow ring with rational coefficients of the Jacobian of a curve. Assume D is a divisor in a base point free of the curve such that the canonical divisor K is a multiple of the divisor D. We find relations between tautological cycles. We give applications for curves having a degree d covering of whose ramification points are all of order d, and then for hyperelliptic curves.      

一锅法合成芳(杂环)胺亚甲基双膦酸四乙酯

以I₂为催化剂,原甲酸三乙酯、芳(杂环)胺和亚磷酸二乙酯为原料,室温无溶剂条件下,一锅合成了系列芳(杂环)胺亚甲基双膦酸四乙酯,收率96%~99%。 当I₂物质的量分数为5%时,产物收率最高。 本方法底物适用范围广,操作简单。 I₂作为催化剂,安全高效。     

Cell polarization energy and its implications for cell migration

Cells usually have a polarized shape in directional cell migration. This cell polarity may result from external cues, such as a gradient of chemo-attractants (chemotaxis), or a gradient of mechanical properties of substrate (durotaxis), and it can also arise from internal cues so that the cells self-polarize spontaneously and maintain the polar motile state for a long time. However, the mechanisms that control cell polarization have not been fully understood, and particularly, the relationship between the polarized shape and cell migration behaviors is not yet clear. In this study, we propose an energy model to study the cell polarization energy by considering the effect of matrix rigidity, cell shape, and organization of the cytoskeleton. We then propose a parameter called “motility factor” for depicting the relationship between the cell shape and the driving force of cell migration. We demonstrate that the fibroblast-like cell shape and keratocyte-like shape both have an optimal polarization angle corresponding to the most stable cell shape. Fibroblast-like cell shape also has an optimal tail length of the polarization. Furthermore, we find that the cell free energy biphasically depends on the matrix rigidity, i.e. that there is an optimum matrix rigidity for the most stable shape. And the motility factor also biphasically depends on the matrix rigidity, but the trends of the dependence are opposite to that of cell's free energy, which implies an optimum matrix rigidity for the highest speed. The optimum matrix rigidity for the most stable cell shape and that for the highest cell speed are consistent, suggesting that the most stable cell shape is favorable to the fastest cell migration. This study provides important insights into the relationship between cell polarization shape and cell migration behaviors.     

电磁波在有缺陷介质中的传播特性

本文以麦克斯韦方程组为基础研究了电磁波在具有缺陷的材料中的传播特性.采用时域有限差分法数值计算了电磁波在具有表面和亚表面缺陷的材料内部传递时电场强度的空间分布.计算结果表明,材料表面、亚表面缺陷扰乱了瞬态电场的均匀分布,导致材料内部某些位置的电场强度成倍增大,从而成为材料热学、力学性质变化的"诱点".文中利用光学知识讨论了缺陷对电磁波调制作用的物理本质.     

CELL AND MOLECULAR BIOMECHANICS: PERSPECTIVES AND CHALLENGES

As an intriguing interdisciplinary research field,cell and molecular biomechanics is at the cutting edge of mechanics in general and biomechanics in particular.It has the potential to provide a quantitative understanding of how forces and deformation at tissue,cellular and molecular levels affect human health and disease.In this article,we review the recent advances in cell and molecular biomechanics,examine the available computational and experimental tools,and discuss important issues including protein deformation in mechanotransduction,cell deformation and constitutive behavior,cell adhesion and migration,and the associated models and theories.The opportunities and challenges in cell and molecular biomechanics are also discussed.We hope to provide readers a clear picture of the current status of this field,and to stimulate a broader interest in the applied mechanics community.