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121.
122.
Avner Ash 《Mathematische Annalen》1983,264(3):277-281
123.
Michael Shwartz Lisa I. Iezzoni Arlene S. Ash Susan M. C. Payne Joseph D. Restuccia 《Annals of Operations Research》1996,67(1):23-44
Data on outcomes of medical care are becoming much more available in health care organizations and systems of care. This will create new opportunities for operations researchers to make contributions to health care policy and management. To provide some background to those new to the health care area, in this article we do the following: (1) provide a brief exposure to major administrative databases that are available and useful for analyzing outcomes data; (2) discuss the strengths and limitations of the diagnostic information contained in these databases; (3) describe several systems that use this information, or in some cases information from the medical record, to determine patient severity, thus providing a basis for severity-adjustment before considering outcomes; and (4) finally, provide an overview of some recent advances in obtaining improved parameter estimates from large databases. 相似文献
124.
Abe K Abt I Ahn CJ Akagi T Ash WW Aston D Bacchetta N Baird KG Baltay C Band HR Barakat MB Baranko G Bardon O Barklow T Bazarko AO Ben-David R Benvenuti AC Bienz T Bilei GM Bisello D Blaylock G Bogart JR Bolton T Bower GR Brau JE Breidenbach M Bugg WM Burke D Burnett TH Burrows PN Busza W Calcaterra A Caldwell DO Calloway D Camanzi B Carpinelli M Cassell R Castaldi R Castro A Cavalli-Sforza M Church E Cohn HO Coller JA Cook V Cotton R Cowan RF Coyne DG D'Oliveira A Damerell CJ Dasu S 《Physical review letters》1995,74(15):2890-2894
125.
Abe K Abt I Ahn CJ Akagi T Allen NJ Ash WW Aston D Baird KG Baltay C Band HR Barakat MB Baranko G Bardon O Barklow T Bazarko AO Ben-David R Benvenuti AC Bienz T Bilei GM Bisello D Blaylock G Bogart JR Bolton T Bower GR Brau JE Breidenbach M Bugg WM Burke D Burnett TH Burrows PN Busza W Calcaterra A Caldwell DO Calloway D Camanzi B Carpinelli M Cassell R Castaldi R Castro A Cavalli-Sforza M Church E Cohn HO Coller JA Cook V Cotton R Cowan RF Coyne DG D'Oliveira A Damerell CJ Daoudi M 《Physical review D: Particles and fields》1995,52(9):4828-4838
126.
Abe K Abt I Ahn CJ Akagi T Allen NJ Ash WW Aston D Baird KG Baltay C Band HR Barakat MB Baranko G Bardon O Barklow T Bazarko AO Ben-David R Benvenuti AC Bienz T Bilei GM Bisello D Blaylock G Bogart JR Bolton T Bower GR Brau JE Breidenbach M Bugg WM Burke D Burnett TH Burrows PN Busza W Calcaterra A Caldwell DO Calloway D Camanzi B Carpinelli M Cassell R Castaldi R Castro A Cavalli-Sforza M Church E Cohn HO Coller JA Cook V Cotton R Cowan RF Coyne DG D'Oliveira A Damerell CJ Daoudi M 《Physical review letters》1995,75(20):3609-3613
127.
A tin oxide, gas-sensitive semiconductor sensor was configured as a gas chromatographic detector and its performance was optimized. Two sensor housings were compared but little difference was found in performance. The flow rate and temperature of the column and the internal heater voltage of the sensor affected both the sensitivity and peak shape. The temperature of the sensor surface was the most critical parameter. Optimal conditions for the gas chromatographic detection of a mixture of alkanes (C1–C5) and hydrogen were identified by using the simplex technique. The detection limit for hydrogen was improved by a factor of five to 20 ppb (v/v), illustrating the value of optimization and the excellent sensitivity of the detector. It is concluded that semiconductor gas sensors offer significant advantages as gas chromatographic detectors for the determination of reducing gases. 相似文献
128.
Anica Markovac Ambalal R. Patel Maurice P. MontagneLa Arthur B. Ash 《Journal of heterocyclic chemistry》1977,14(1):147-148
The preparation of 4-(3-nitrophenyl)-2-pieoline (3) was accomplished in one step by the Zecher-Krohnke ring-closure reaction. Compound 3 is the starling material for 2-lormyl-4-(3-arninophenyl)pyridine thiosemicarbazone (4-APPT), a promising antineoplastie agent. 相似文献
129.
Ash WW Band HR Camporesi T Chadwick GB Delfino MC De Sangro R Ford WT Gettner MW Goderre GP Groom DE Hurst RB Johnson JR Lau KH Lavine TL Leedy RE Maruyama T Messner RL Moromisato JH Moss LJ Muller F Nelson HN Peruzzi I Piccolo M Prepost R Pyrlik J Qi N Read AL Ritson DM Ronga F Rosenberg LJ Shambroom WD Sleeman JC Smith JG Venuti JP Verdini PG von Goeler E Wald HB Weinstein R Wiser DE Zdarko RW 《Physical review letters》1987,58(11):1080-1083
130.
Amit Fischer Avner Ehrlich Yevgeni Plotkin Yu Ouyang Klil Asulin Ioannidis Konstantinos Prof. Chunhai Fan Prof. Yaakov Nahmias Prof. Itamar Willner 《Angewandte Chemie (International ed. in English)》2023,62(43):e202311590
The combination of gene therapy and immunotherapy concepts, along recent advances in DNA nanotechnology, have the potential to provide important tools for cancer therapies. We present the development of stimuli-responsive microcapsules, loaded with a viral immunogenetic agent, harnessing the immune response against the Coronavirus Disease 2019, COVID-19, to selectively attack liver cancer cells (hepatoma) or recognize breast cancer or hepatoma, by expression of green fluorescence protein, GFP. The pH-responsive microcapsules, modified with DNA-tetrahedra nanostructures, increased hepatoma permeation by 50 %. Incorporation of a GFP-encoding lentivirus vector inside the tumor-targeting pH-stimulated miRNA-triggered and Alpha-fetoprotein-dictated microcapsules enables the demonstration of neoplasm selectivity, with approximately 5,000-, 8,000- and 50,000-fold more expression in the cancerous cells, respectively. The incorporation of the SARS-CoV-2 spike protein in the gene vector promotes specific recognition of the immune-evading hepatoma by the COVID-19-analogous immune response, which leads to cytotoxic and inflammatory activity, mediated by serum components taken from vaccinated or recovered COVID-19 patients, resulting in effective elimination of the hepatoma (>85 % yield). 相似文献