Synthese und Kristallstruktur einer Neuen hexagonalen Modifikation von Al2S3 mit fünffach koordiniertem Aluminium

Synthesis and Crystal Structure of a Novel Hexagonal Modification of Al₂S₃ with Five-coordinated Aluminum A new hexagonal high temperature modification of Al₂S₃ could be prepared by chemical vapour transport with iodine (860 → 750°C) or by annealing of α -Al₂S₃ at 550°C. According to the single crystal X-ray structure determination the novel form of Al₂S₃ crystallizes in space group P 6₁ (No. 169) with a = 6.491(1), c = 17.169(4) Å, V = 626.5 ų, Z = 6; R = 0.0253. In this modification one half of the aluminum atoms are tetrahedrally coordinated [d(Al? S): 2.226–2.267 Å], whereas the other half are in trigonal bipyramidal coordination of five S atoms with bond lengths of 2.272–2.315 Å (equatorial) and 2.495–2.521 Å (axial). Aluminum in AlS₅ coordination is observed for the first time in this compound. The crystal structure is isotypic to In₂Se₃ and AlInS₃. In addition, results of a refinement of the α -Al₂S₃ crystal structure are reported which were obtained on crystals prepared also by chemical vapour transport with iodine.     

Structure and diffusion in amorphous aluminum silicate: a molecular dynamics computer simulation

The amorphous aluminum silicate (Al2O3)2(SiO2) [AS2] is investigated by means of large scale molecular dynamics computer simulations. We consider fully equilibrated melts in the temperature range 6100 K> or =T> or =2300 K as well as glass configurations that were obtained from cooling runs from T=2300 to 300 K with a cooling rate of about 10(12) K/s. Already at temperatures as high as 4000 K, most of the Al and Si atoms are fourfold coordinated by oxygen atoms. Thus, the structure of AS2 is that of a disordered tetrahedral network. The packing of AlO4 tetrahedra is very different from that of SiO4 tetrahedra in that Al is involved with a relatively high probability in small-membered rings and in triclusters in which an O atom is surrounded by four cations. We find as typical configurations two-membered rings with two Al atoms in which the shared O atoms form a tricluster. On larger length scales, the system shows a microphase separation in which the Al-rich network structure percolates through the SiO2 network. The latter structure gives rise to a prepeak in the static structure factor at a wave number q=0.5 A(-1). A comparison of experimental x-ray data with the results from the simulation shows good agreement for the structure function. The diffusion dynamics in AS2 is found to be much faster than in SiO2. We show that the self-diffusion constants for O and Al are very similar and that they are by a factor of 2-3 larger than the one for Si.     

The iodine supply of humans depending on site, food offer and water supply

In Central Europe, the iodine content of weathered soils of new red sandstone, Muschelkalk, keuper and lower strata of new red sandstone, which developed from marine sediment is low. Boulder clays and diluvial sands also exhibit low iodine concentrations. In the same areas, the iodine concentration of drinking water decreases from 9 to 1 g/l with increasing distance from the oceans. Cereals and foodstuffs produced from them are extremely iodine-poor. The iodine content of plants increases with the proportion of leaves. Soil contamination raises the iodine content of foodstuffs and improves the iodine supply of animals. The iodination of mineral mixtures increased the iodine content of cow's milk from 17 to 81 g/l. The iodination of packed cooking salt and of the mineral mixtures for cattle and pigs resulted in a mean increase of the iodine intake of adults from about 30 g/day to 48 and 59, respectively. Although iodine intake remained considerably below the calculated requirement for adults (100 to 150 g/day), it led to the disappearance of Struma konnata and reduced the frequency of struma in children.     

Genes encoding enzymes responsible for biosynthesis of L-lyxose and attachment of eurekanate during avilamycin biosynthesis

The oligosaccharide antibiotic avilamycin A is composed of a polyketide-derived dichloroisoeverninic acid moiety attached to a heptasaccharide chain consisting of six hexoses and one unusual pentose moiety. We describe the generation of mutant strains of the avilamycin producer defective in different sugar biosynthetic genes. Inactivation of two genes (aviD and aviE2) resulted in the breakdown of the avilamycin biosynthesis. In contrast, avilamycin production was not influenced in an aviP mutant. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue. Finally, AviE2 was expressed in Escherichia coli and the gene product was characterized biochemically. AviE2 was shown to convert UDP-D-glucuronic acid to UDP-D-xylose, indicating that the pentose residue of avilamycin A is derived from D-glucose and not from D-ribose. Here we report a UDP-D-glucuronic acid decarboxylase in actinomycetes.     

Two-dimensional double-quantum 2H NMR spectroscopy in the solid state under OMAS conditions: correlating 2H chemical shifts with quasistatic line shapes.

Solid-state 2H NMR spectroscopy is a well-established and versatile method to study molecular orientation and dynamics in selectively deuterated samples. Herein, we introduce a 2D 2H double-quantum (DQ) NMR experiment performed under fast magic-angle spinning with a slight offset of the magic angle (OMAS). The experiment combines 2H chemical-shift resolution with DQ-filtered quasistatic 2H line shapes. In this way, it is possible to separate 2H resonances and to independently determine 2H quadrupole couplings at multiple sites. While 2H chemical shifts are resolved in the 2H DQ dimension, the quadrupole parameters can be obtained from characteristic line shapes which are reintroduced in the second dimension by the magic-angle offset. The 2D 2H DQ OMAS experiment is demonstrated on L-histidine which was deuterated at multiple sites by recrystallisation from D2O.     

Reduction of 1,4-dichlorobut-2-yne by titanocene to a 1,2,3-butatriene. Formation of a 1-titanacyclopent-3-yne and a 2,5-dititanabicyclo[2.2.0]hex-1(4)-ene

The 2,5-dititanabicyclo[2.2.0]hex-1(4)-ene (bis-titanocene-mu-(Z)-1,2,3-butatriene complex)3 is formed starting from [Cp2Ti(eta2-Me3SiC2SiMe3)] by in situ generated titanocene and 1,4-dichlorobut-2-yne via the 1-titanacyclobut-3-yne (2).     

Untersuchungen zur Bildung von Doppelringsilicationen in Trimethyl-(2-hydroxyethyl)ammoniumsilicatlösungen

Investigation on the Formation of Double-ring Silicate Ions in Trimethyl-(2-hydroxyethyl) Ammoniumsilicate Solutions The formation of double-four ring silicate ions have been investigated after the mixing of Tetramethoxysilan with Trimethyl-(2-hydroxyethyl)ammoniumhydroxide in the molar ratio 1:1 (c_SiO2 = 1.53 mol · kg^?1) in dependence of the time. About 20–30% of the rapid hydrolysing esters has reacted to double-three- and double-four ring ions after a short time, whereas 70–80% first condense to oligomers and polymers. In the further course of reaction also the oligomers, the polymers and the intermediate formed double-three-ring species changes to double-four-ring ions. After three hours about 90% of the silicon dioxide is in the double-four-ring constitution.     

Three‐Component Reactions with (S)‐Methyl Pyroglutamate: An Efficient Way to Diversely Substituted Asymmetric Amidocyclohexenes

Chiral N‐dienyl lactams are crucial building blocks for the synthesis of complex organic compounds. However, their generation is rather challenging. This paper reports the novel one‐pot reaction of (S)‐methyl pyroglutamate as the a mide component with different a ldehydes and d ienophiles (AAD reaction) to give novel chiral 1‐amido‐2‐cyclohexenes. The corresponding N‐dienyl lactams generated in situ undergo subsequent Diels–Alder reactions in good yield and diastereoselectivity. The scope and limitations of the three‐component protocol were investigated. X‐ray and NMR spectroscopic analysis of the products as well as DFT calculations of the intermediates were also performed to explain the observed stereoselectivity and structural features.