Inclusive ϕ production inK − p interactions at 110 GeV/c and search for structure in φ π−

Results on inclusive ? production inK ^? p interactions at 110 GeV/c are presented. The production cross section is found to be larger than in πp andpp interactions at similar energies, suggesting OZI allowed \(s\bar s\) fusion to be the dominant mechanism in ? production. Thex distributions of ? and \(\bar K^{*0} \) are found to be similar to each other over the entirex range suggesting an overall strangeness suppression factor of 0.20±0.04 in the sea to be the dominant source of the difference in the cross section for ? and \(\bar K^{*0} \) . There is no evidence of a narrowφπ ^? state around 2.1 GeV/c² as suggested byK ⁺ experiments, but there is some excess of events in the region 1.94?1.98 GeV/c² consistent with theF-meson mass as observed ine ⁺ e ^? experiments.     

Determination of traces of palladium using radioactive zinc dithizonate as a reagent

A radioreagent method for the analysis of traces of palladium using radioactive zinc dithizonate as the reagent has been developed. The method is rapid, highly selective and palladium concentration down to 2 g present in 10 ml solution can be measured.     

Binding studies of sodium dodecyl benzene sulphonate with poly(N-vinyl-2-pyrrolidone)

The binding of sodium dodecyl benzene sulphonate (SDBS) with poly(N-vinyl-2-pyrrolidone) (PVP) has been investigated at 303.15 and 313.15 K using equilibrium dialysis, surface tension, viscosity, ultrasound velocity and ultrasound absorption techniques. From each of these studies four distinct regions of SDBS-PVP interactions were observed. Interaction of SDBS with PVP was found to involve the binding of surfactant dimers with the polymer molecule followed by usual micellization. The binding data has been analyzed in terms of various models of polymer-surfactant interaction.     

Substitutions of coordinated salicylaldehyde and its Schiff bases

Summary Several bis/tris-salicylaldehyde, salicylaldimine and salicyalethylenediimine chelates of cobalt(III), chromium(III), cobalt(II), nickel(II) and copper(II) readily react with various brominating agents and undergo α-bromo/cyano/succinimido substitution, with or without accompanying bromine substitution of the aryl ring. The selectivity of these reactions on the metal-coordinated salicylaldehyde derivatives allows the preparation in 50–80% yield of hitherto unreported specific α-bromo products. The substituted organic compounds could be isolated by demetallation of the chelate products.     

Purification of monoclonal antibodies from cell culture supernatants using a modified zirconia based cation-exchange support

A method suitable for the isolation of monoclonal antibodies (Mabs) is described. The protocol utilizes a zirconia based column modified with ethylenediamine-N,N'-tetra(methylenephosphonic) acid to create a novel cation-exchange chromatographic support. Initial experiments using a linear salt gradient demonstrate the ability of this support to efficiently separate Mab from transferrin and bovine serum albumin in a model matrix. Results of the purification of Mab from an actual cell culture supernatant over a range in protein concentrations are also shown. Analyses by enzyme-linked immunosorbent assay and gel electrophoresis demonstrate that Mabs can be recovered from a cell culture supernatant at high yield (92-98%) and high purity (> 95%) in a single chromatographic step.     

Heterocyclic inflammation inhibitors

Non steroidal anti-inflammatory drugs are the most widely used medicines for relief of pain. These drugs have some side effects, particularly toxicity in the gastrointestinal tract and kidneys. Various approaches have been used for obtaining safer anti-inflammatory drugs. In this review we have summarized the recent developments in the following areas; (i) mode of action of NSAIDs (ii) Role of COX-1 & COX-2 in inflammation, (iii) Different approaches used to improve gastric tolerance i.e. chemical manipulation, formulation & co-administration, development of non specific (COX-1 & COX-2 inhibitors) and specific (COX-2 inhibitors) inflammation inhibitors, and development of inflammation inhibitors having a mode of action other than COX-1 & COX-2 inhibition. We have also focused on the safety of COX-2 inhibitors and the synthesis of heterocyclic compounds and their role as inflammation inhibitors.     

Determination of Se,Cd, and Hg in an aquatic environment of Bombay by substoichiometric neutron activation analysis

The toxicity of Se, Cd, and Hg as environmental pollutants and the impact of these elements on the aquatic ecosystem is undisputed. The present paper reports an investigation of the concentration of Cd, Se, and Hg in an aquatic environment of a large metropolitan city like Bombay. As the toxicity of these elements manifests itself at micro and submicro levels, the very sensitive technique of neutron activation analysis was employed. A sequential substoichiometric extraction technique for the separation of radiochemically pure²⁰³Hg,⁷⁵Se, and^115–115mCd from the neutron irradiated target has also been employed.     

Simulation of the Adhesion of Particles to Surfaces

The removal of micrometer and submicrometer particles from dielectric and metal films represents a challenge in postchemical mechanical polishing cleaning. Proper modeling of the adhesive force between contaminant particles and these films is needed to develop optimal solutions to postchemical mechanical polishing cleaning. We have previously developed and experimentally validated a model to describe the adhesion between spherical particles and thin films. This simulation expands previous models to characterize the adhesive interaction between asymmetrical particles, characteristic of a polishing slurry, and various films. Our simulation accounts for the contact area between particles and substrates, as well as the morphology of the surfaces. Previous models fail to accurately describe the contact of asymmetrical particles interacting with surfaces. By properly accounting for nonideal and geometry and morphology, the simulation predicts a more accurate adhesive force than predictions based upon an ideal van der Waals model. The simulation is compared to experimental data taken for both semi-ideal particle-substrate systems (polystyrene latex spheres in contact with silicon films) and asymmetrical systems (alumina particles in contact with various films). Copyright 2001 Academic Press.     

Computation of density of perfluoroalkyl methacrylates: a molecular modeling approach

Molecular dynamics simulations have been carried out on different perfluoroalkyl methacrylates to predict their densities. Density calculations on selected perfluoroalkyl methacrylates have been performed using molecular dynamics in the NPT ensemble by employing COMPASS force field. The calculated density values compared quite well with the experimental data reported in the literature.