Non-Cayley Vertex-Transitive Graphs of Order Twice the Product of Two Odd Primes

For a positive integer n, does there exist a vertex-transitive graph Γ on n vertices which is not a Cayley graph, or, equivalently, a graph Γ on n vertices such that Aut Γ is transitive on vertices but none of its subgroups are regular on vertices? Previous work (by Alspach and Parsons, Frucht, Graver and Watkins, Marusic and Scapellato, and McKay and the second author) has produced answers to this question if n is prime, or divisible by the square of some prime, or if n is the product of two distinct primes. In this paper we consider the simplest unresolved case for even integers, namely for integers of the form n = 2pq, where 2 < q < p, and p and q are primes. We give a new construction of an infinite family of vertex-transitive graphs on 2pq vertices which are not Cayley graphs in the case where p ≡ 1 (mod q). Further, if p ? 1 (mod q), p ≡ q ≡ 3(mod 4), and if every vertex-transitive graph of order pq is a Cayley graph, then it is shown that, either 2pq = 66, or every vertex-transitive graph of order 2pq admitting a transitive imprimitive group of automorphisms is a Cayley graph.     

Caractérisation du module d'une fonction additive à l'aide d'une équation fonctionnelle

Sans résumé     

‘All‐supramolecular’ Nanocapsules from Low‐Molecular Weight Ureas Through Interfacial Addition Reaction in Miniemulsion

This contribution presents a new strategy for preparing nanocapsules with a shell made of a supramolecular polymer which repeating units are held together by reversible interactions rather than covalent bonds. These nanocapsules were prepared in classical miniemulsion through interfacial addition reaction of a diisocyanate (IPDI) and a monoamine (iBA), forming low‐molecular weight bis‐ureas moieties which are strong self‐complementary interacting molecules through hydrogen‐bonding. The nanocapsules present a diameter around 100 nm, and MALDI‐TOF MS and ¹H NMR analyses confirm the expected molecular characteristics for the shell. This strategy opens the scope of a new type of nanomaterials exhibiting stimuli‐responsiveness due to the reversible interaction linking the repeating units.

     

Symplectic automorphisms on Kummer surfaces

Nikulin proved that the isometries induced on the second cohomology group of a K3 surface X by a finite abelian group G of symplectic automorphisms are essentially unique. Moreover he computed the discriminant of the sublattice of H²(X,\mathbbZ){H^2(X,\mathbb{Z})} which is fixed by the isometries induced by G. However for certain groups these discriminants are not the same as those found for explicit examples. Here we describe Kummer surfaces for which this phenomena happens and we explain the difference.     

Reversible activation of diblock copolymer monolayers at the interface by pH modulation, 2: Membrane interactions at the solid/liquid interface

A monolayer of the pH-responsive poly[2-(dimethylamino)ethyl methacrylate-block-methyl methacrylate] diblock copolymer [PDMAEMA-PMMA] was transferred from the air/water interface to a silicon substrate for evaluation as a tunable interlayer between biological material and solid substrates. Specular neutron reflectivity experiments revealed that the weak polyelectrolyte PDMAEMA chains at the solid/liquid interface can be reversibly activated by pH modulation. The thickness, scattering length density, and surface roughness of the polymer film can be systematically controlled by pH titration. As a simple model of plasma membranes, a lipid bilayer was deposited onto the polymer film. The membrane-substrate interaction was characterized by neutron reflectivity experiments, demonstrating that the membrane-substrate distance could be reversibly regulated by pH titration. These results confirm the potential of stimuli-responsive polymers for precise control of cell-surface interactions.     

The Moduli Space of 3-Dimensional Associative Algebras

In this article, we give a classification of the 3-dimensional associative algebras over the complex numbers, including a construction of the moduli space, using versal deformations to determine how the space is glued together.     

Fucoxanthin Holds Potential to Become a Drug Adjuvant in Breast Cancer Treatment: Evidence from 2D and 3D Cell Cultures

Fucoxanthin (Fx) is a carotenoid derived from marine organisms that exhibits anticancer activities. However, its role as a potential drug adjuvant in breast cancer (BC) treatment is still poorly explored. Firstly, this study investigated the cytotoxic effects of Fx alone and combined with doxorubicin (Dox) and cisplatin (Cis) on a panel of 2D-cultured BC cell lines (MCF7, SKBR3 and MDA-MB-231) and one non-tumoral cell line (MCF12A). Fucoxanthin induced cytotoxicity against all the cell lines and potentiated Dox cytotoxic effects towards the SKBR3 and MDA-MB-231 cells. The combination triggering the highest cytotoxicity (Fx 10 µM + Dox 1 µM in MDA-MB-231) additionally showed significant induction of cell death and genotoxic effects, relative to control. In sequence, the same combination was tested on 3D cultures using a multi-endpoint approach involving bioactivity assays and microscopy techniques. Similar to 2D cultures, the combination of Fx and Dox showed higher cytotoxic effects on 3D cultures compared to the isolated compounds. Furthermore, this combination increased the number of apoptotic cells, decreased cell proliferation, and caused structural and ultrastructural damages on the 3D models. Overall, our findings suggest Fx has potential to become an adjuvant for Dox chemotherapy regimens in BC treatment.     

A Characterization of Nilpotent Leibniz Algebras

W. A. Moens proved that a Lie algebra is nilpotent if and only if it admits an invertible Leibniz-derivation. In this paper, using the definition of a Leibniz-derivation from Moens (2010), we show that a similar result for non-Lie Leibniz algebras is not true. Namely, we give an example of non-nilpotent Leibniz algebra that admits an invertible Leibniz-derivation. In order to extend the results of the paper by Moens (2010) for Leibniz algebras, we introduce a definition of a Leibniz-derivation of Leibniz algebras that agrees with Leibniz-derivation of the Lie algebra case. Further, we prove that a Leibniz algebra is nilpotent if and only if it admits an invertible Leibniz-derivation of Definition 3.4. Moreover, the result that a solvable radical of a Lie algebra is invariant with respect to a Leibniz-derivation was extended to the case of Leibniz algebras.     

Localization and delocalization of eigenvectors for heavy-tailed random matrices

Consider an $n \times n$ Hermitian random matrix with, above the diagonal, independent entries with $\alpha $ -stable symmetric distribution and $0 < \alpha < 2$ . We establish new bounds on the rate of convergence of the empirical spectral distribution of this random matrix as $n$ goes to infinity. When $1 < \alpha < 2$ and $ p > 2$ , we give vanishing bounds on the $L^p$ -norm of the eigenvectors normalized to have unit $L^2$ -norm. On the contrary, when $0 < \alpha < 2/3$ , we prove that these eigenvectors are localized.