Influence of Annealing Temperature on Structure, Optical Loss and Laser-Induced Damage Threshold of TiO2 Thin Films

TiO2 thin films are prepared on fused silica with conventional electron beam evaporation deposition. After annealed at different temperatures for 4h, the spectra and XRD patterns of the TiO2 thin film are obtained. Weak absorption of coatings is measured by the surface thermal lensing technique, and laser-induced damage threshold （LIDT） is determined. It is found that with the increasing annealing temperature, the transmittance of TiO2 films decreases. Especially when coatings are annealed at high temperature over 1173K, the optical loss is very serious. Weak absorption detection indicates that the absorption of coatings decreases firstly and then increases, and the absorption and defects play major roles in the LIDT of TiO2 thin films.     

Graded Index 532HR/1064HT Filter by Glancing Angle Deposition

Glancing angle deposition is a novel method to prepare graded index coatings. By using this method and physical vapour deposition, ZrO2 is used to engineer graded index filter on BK7 glass substrate. Controlling the deposition rate and the periodic oscillation of oblique angle of deposited material, a 10-period graded index ZrO2 filter with high reflection near 532nm and high transmittance at wavelength 1064nm is fabricated. The causes of difference between the theoretical and experimental results are discussed in detail. The material properties and electron gun nonlinearity are possibly the main origins of the difference, which result in the variations in both thickness control and deposition rate of the film material.     

Impact of organic contamination in vacuum on laser-induced damage threshold of TiO_2/SiO_2 dielectric mirrors

The influence of organic contamination in vacuum on the laser-induced damage threshold (LIDT) of coatings is studied.TiO_2/SiO_2 dielectric mirrors with high reflection at 1064 nm are deposited by the electronbeam evaporation method and their LIDTs are measured in vacuum and atmosphere,respectively. It is found that the contamination in vacuum is easily attracted to optical surfaces because of the low pressure and becomes the source of damage,O_2 molecules in vacuum with contamination can accelerate the laser-induced damage by observing LIDT and damage morphologies.LIDTs of mirrors have a little change in vacuum compared with in atmosphere when the organic contamination is wiped off.The results indicate that organic contamination is a significant reason to decrease the LIDT in vacuum.     

高效液相色谱同时测定芦荟中8种蒽醌类物质的含量

建立了高效液相色谱(HPLC)-二级阵列检测器(DAD)同时测定芦荟中8种蒽醌类物质(芦荟苷B、芦荟苷A、大黄素-8-O-葡萄糖苷、芦荟大黄素、大黄酸、大黄素、大黄酚、大黄素甲醚)的方法。样品经5 mL 90%甲醇在30℃超声提取20 min后,以甲醇-乙腈-0.05%磷酸溶液为流动相梯度洗脱,经Eclipse XDB-C_(18)柱分离,多波长同时检测。8种蒽醌类待测物在14 min内获得满意的分离。方法的检出限(S/N=3)为0.55~1.02μg/g,样品平均加标回收率为90.3%~107.8%,RSD为4.8%。     

基于纳升电喷雾-轨道阱超高分辨质谱对完整单克隆抗体药物进行分子量测定及糖型鉴定的条件探究

整体分子量测定和糖型鉴定是抗体药物研发及生产中不可或缺的表征内容,而在完整蛋白层面进行测定可获得最为直接的测定结果。实现此类测定有赖于可提供较高分辨能力及质量精度的仪器;测定中涉及的相对复杂的参数设置可能受多种条件的干扰而产生误导性结果。该研究考察了利用纳升电喷雾离子源-轨道阱质谱仪以非变性质谱方式测定完整单克隆抗体药时,仪器分辨率、源内裂解、碰撞诱导碎裂、溶液组成等条件对单克隆抗体药物分子量及糖型测定结果的影响,以期为此类质谱分析提供有益的借鉴。     

化学分析实验室质量控制图的建立和应用

正化学分析实验室的内部质量控制是实验室对自己的分析方法和操作程序进行的持续的、严格的评估,CNAS-CL10:2012《检测和校准实验室能力认可准则在化学领域的应用说明》第5.9a)条规定:实验室应建立和实施充分的内部质量控制计划,以确保并证明检测过程受控以及检测结果的准确性和可靠性。质量控制图是内部质量控制的一种重要工具,是将控制值按照特定顺序绘制在图中,它包含一条中心线(CL),通常为数据的平均值,还包含由统计方法确定的两条控制限,位于中心线的各一侧,称为上控制限(UCL)和下控制限(LCL)。     

CuInS2量子点阻变效应

采用改进的热分解法制备了具有半导体效应的CuInS₂量子点,量子点尺寸均匀、大小为4.2 nm。组装的Au/CuInS₂/FTO阻变存储器件表现出典型的双极性阻变特点,其开态电压为-3.8 V,关态电压为4 V,ON/OFF开关比约为10³。对器件的I-V特性曲线线性拟合发现,器件的阻变机制在高阻态时表现为空间限制电荷（SCLC）传导机制,在低阻态时表现为欧姆传导机制。器件的阻变特性主要是由于电荷被CuInS₂薄膜中的缺陷产生的势阱捕获导致。通过调节陷阱势垒高度引起电荷在陷阱中移动,导致导电通路的产生和断裂,使器件处于高阻态和低阻态。     

不同波长激光同时辐照薄膜热效应研究

通过分析两个不同波长激光同时辐照下薄膜体内驻波场分布并求解热传导方程,得到1 064 nm激光和355 nm激光在三倍频分离膜内共同作用下二维温度场分布.研究表明：1 064 nm激光和355 nm激光共同作用引起薄膜体内的温升峰值高于相同能量1 064 nm激光单独作用引起的薄膜体内的温升峰值,低于相同能量355 nm激光单独作用引起的薄膜体内的温升峰值.     

局域浓度调控扩散系数的次氯酸-碘离子-丙二酸系统图灵斑图形成中的反常扩散

通过数值模拟及振幅方程解析解方法,从实空间和倒空间分析了受局域浓度扩散系数调控下次氯酸-碘离子-丙二酸反应扩散系统图灵斑图形成的扩散机理.在零扩散系数调节下,斑图形成为典型的菲克扩散;而在负向正向扩散系数调节下,斑图的形成依赖欠扩散和超扩散.图灵系统的浓度稳态振幅对随机初始条件敏感性随局域浓度扩散调控系数k的增大而增加.