Synthesis and Antifungal Activity of Novel Chiral α-Aminophosphonates Containing Fluorine Moiety

Chiral α-aminophosphonates were synthesized using （R） or （S）-1-phenylethylamine in the presence of BF3·Et2O under microwave irradiation in moderate to good yields. The new compounds were identified by ^1H NMR, ^19F NMR, IR and elemental analysis. Their antifungal activities were evaluated and some compounds were found to exhibit excellent antifungal activities. To the best of our knowledge, this is the first report on antifungal activity of chiral α-aminophosphonates containing fluorine moiety.     

云南丽江野生香薷籽微量元素成分分析

应用电感耦合氩等离子体原子发射光谱仪（ICP－AES），对采自云南丽江的野生香薷籽进行了微量元素成分分析，其结果为开发利用野生香薷籽提供了依据。     

O,O'-二烷基-α-(取代苯并噻唑-2-基)氨基-(取代苯基甲基)膦酸酯的合成与抗烟草花叶病毒活性

采用无溶剂无催化剂合成方法, 分别进行了以O,O'-二烷基亚磷酸酯、3,4,5-三甲氧基苯甲醛、2-氨基取代苯并噻唑为原料的类Mannich一锅法合成反应研究, 经合成筛选, 优选出控制反应温度100 ℃, 无溶剂、无催化剂加热反应120 min的合成方法, 实验结果表明该方法经济、简便、对环境友好. 经元素分析, IR, ¹H NMR, ¹³C NMR对所合成的化合物进行了结构确认和表征. 培养并测定了化合物4a的晶体结构. 初步生物活性测试表明, 化合物具有一定的抗烟草花叶病毒活性.     

肟类衍生物的合成与农药生物活性的研究进展

肟类化合物具有优良的杀虫、杀菌及除草活性, 不少品种还具有低毒、低残留等优点. 目前该类化合物的分子设计和合成及生物活性研究是农药创制的热点之一. 按照不同的生物活性和结构进行分类, 对近年来肟类化合物在农业中应用作了综述, 着重从分子合成和生物活性进行讨论, 并对它的发展趋势、应用前景作了进一步展望.     

O,O''''-二烷基-α-(取代苯并噻唑-2-基)氨基-(取代苯基甲基)膦酸酯的合成与抗烟草花叶病毒活性

采用无溶剂无催化剂合成方法,分别进行了以O,O'-二烷基亚磷酸酯、3,4,5-三甲氧基苯甲醛、2-氨基取代苯并噻唑为原料的类Mannich一锅法合成反应研究,经合成筛选,优选出控制反应温度100℃,无溶剂、无催化剂加热反应120min的合成方法,实验结果表明该方法经济、简便、对环境友好.经元素分析,IR,1HNMR,13CNMR对所合成的化合物进行了结构确认和表征.培养并测定了化合物4a的晶体结构.初步生物活性测试表明,化合物具有一定的抗烟草花叶病毒活性.     

Fabry–Prot resonance coupling associated exceptional points in a composite grating structure

The exceptional point(EP) is a significant and attractive phenomenon in an open quantum system. The scattering properties of light are similar to those in the open quantum system, which makes it possible to achieve EP in the optic system. Here we investigate the EP in a Fabry–P′erot(F–P) resonant coupling structure. The coupling between different types of F–P resonances leads to a near zero reflection, which results in a degeneration of eigenstates and thus the appearing of EP. Furthermore, the multi-wavelength EPs and unidirectional invisibility can be achieved which may be used in integrated photonics systems.     

5-吡唑酰胺类化合物的合成及其杀虫活性研究

采用活性基团拼接法,以2,3-二氯吡啶和马来酸二乙酯为起始原料,由胺基化合物与中间体6合成了10个新的5-吡唑酰胺类化合物,通过IR,1HNMR,13CNMR和元素分析对其结构进行了表征.初步生物活性测试结果表明,在100μg/mL浓度下,化合物7a～7j具有一定杀虫活性.其中化合物7a和7d对褐飞虱的防治效果分别为57.6%和64.4%,与对照药剂噻嗪酮杀虫活性基本相当.作用机制测试结果表明7d对褐飞虱乙酰胆碱酯酶活性的抑制率为75.21%,高于噻嗪酮对褐飞虱乙酰胆碱酯酶的抑制率(52.17%).     

Non-Isothermal Kinetics of the Decomposition Reaction of Cluster [Ag3WS3Br]（PPh3）3 and [Cu3WS3Br]（PPh3）3

The thermal behaviors of clusters [Ag3WS3Br](PPh3)3 and [Cu3WS3Br](PPh3)3 (PPh3=triphenyl phosphine) in a nitrogen atmosphere were studied under the non-isothermal conditions by simultaneous TG-DTG-DSC and EDS techniques. The results showed that the evolution of PPh3 generally proceeded before the release of the other moiety in one or two step-mode. The mechanisms, the kinetic and the thermodynamic parameters for decomposition of PPh3 of both clusters were determined and calculated by jointly using several methods, which showed that its evolution was controlled by Avrami-Erofeev equation. The results also showed that there was no new stable phase composed of W-Ag(Cu)-S-Br after release of organic moiety PPh3 and that CVD method was not applicable to their further processing.     

应用激光和CCD的远程位移检测实验研究

研究了利用线阵CCD对远程位移激光检测的方法 ,设计了光路、信号处理电路 ,并通过实验验证了该方法的可行性。该检测手段成本相对较低 ,具有自动、连续在线检测 ,非接触 ,精度高的特点。