Synthesis and Crystal Structure of MnSm_4(SiO_4)_3O

ＳｙｎｔｈｅｓｉｓａｎｄＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆＭｎＳｍ_４（ＳｉＯ_４）_３Ｏ￥ＣｈｉＬｉ－Ｓｈｅｎｇ；ＤｅｎｇＳｈｕｉ－Ｑｕａｎ；ＺｈｕａｎｇＨｏｎｇ－Ｈｕｉ；ＨｕａｎｇＪｉｎ－Ｓｈｕｎ；（ＳｔａｔｅＨｅｙｌａｂｏｒａｔｏｒｙｏｆＳｔｒ?..     

Synthesis and Crystal Structure of Trigadolinium Bromoorthosilicate，Gd_3Br（SiO_4）_2

ＳｙｎｔｈｅｓｉｓａｎｄＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆＴｒｉｇａｄｏｌｉｎｉｕｍＢｒｏｍｏｏｒｔｈｏｓｉｌｉｃａｔｅ，Ｇｄ_３Ｂｒ（ＳｉＯ_４）_２ＭａｏＪｉａｎｇ－Ｇａｏ；ＺｈｕａｎｇＨｏｎｇ－Ｈｕｉ；ＨｕａｎｇＪｉｎ－Ｓｈｕｎ（ＳｔａｔｅＫｅ?..     

原子发射光谱分析

本文是《分析试验室》期刊单年度定期评述中关于原子发射光谱分析的第三篇综述文章。文中对１９９３－１９９４年期间我国在ＡＥＳ领域所取得的主要进展作了简要的评述。评述内容包括基础理论、应用研究、仪器研制、新方法建立以及一般样品分析。研究领域主要涉及到电感耦合等离子体原子发射光谱法，微波等离子体原子发射光谱法，电弧和火花原子发射光谱法，辉发放电原子发射光谱法和亚稳态能量转移光谱法等。引用文献２１１篇。     

Microwave‐assisted synthesis of phenylenedi(4′,4“‐tetrahydroquinoline) and di(4′,4”‐tetrahydropyridine) derivatives

The synthesis of bifunctional pyridine and quinolione derivatives were investigated using terephthalic and isophthalic aldehydes as a precursor. The reaction proceeds under microwave irradiation with good yield (70–92%) and short reaction time (7–9 min.). We provide a rapid and efficient method of synthesizing a range of bifunctional monocyclic and bicyclic products related to 1,4‐dihydropyridines (1,4‐DHPs).     

Molecularly imprinted sol-gel nanotubes membrane for biochemical separations

In this study, we report a simple procedure for applying molecular imprinting functional groups to the inner surfaces of the template-synthesized sol-gel nanotubes for chemical separation of estrone. The silica nanotubes were synthesized within the pores of nanopore alumina template membranes using a sol-gel method by simultaneous hydrolysis of a silica monomer-imprinted molecule complex and tetraethoxysilane (TEOS). A covalent imprinting strategy was employed by generating a sacrificial spacer through the reaction of the isocyanate group of 3-(triethoxysilyl)propyl isocyanate and a phenol moiety of estrone to form a thermally cleavable urethane bond. This allowed us to remove the imprinted estrone by simple thermal reaction and to simultaneously introduce functional groups into the cavity formed by the silica nanotubes. Experiments indicated that estrone could be bound selectively by such an approach and have a binding affinity of 864 +/- 137 (n = 3).     

用含偶氮基的聚苯乙烯大分子引发剂合成两亲性嵌段共聚物

采用含偶氮基的聚苯乙烯预聚物（ＰＳ ＡＣＰＣ）作为引发剂，合成了苯乙烯（Ｓｔ）分别与甲基丙烯酸（ＭＡＡ）、甲基丙烯酸（β 羟丙酯）（ＨＰＭＡ）的嵌段共聚物，考察了ＰＳ ＡＣＰＣ引发第二单体的聚合反应行为，以及影响第二单体转化率和均聚物含量、共聚物组成的因素．用溶解性、凝胶渗透色谱（ＧＰＣ）、红外光谱（ＩＲ）、核磁共振（ＮＭＲ）、动态接触角（ＤＣＡ）等表征了嵌段共聚物．     

顺磁性聚酯金属配合物的合成及其驰豫性能的研究

本文通过二乙三胺五乙酸（ＤＴＰＡ）或乙二胺四乙酸（ＥＤＴＡ）的双酸酐与二元醇或二元酚进行聚合反应，制备了两个系列共１５种新的聚酯型大分子配体及其顺磁性金属配合物，用核磁、红外光谱以及元素分析表征了配体和配合物的结构。初步试验结果表明，与相应的小分子金属配合物相比，聚酯金属配合物具有较高的弛豫性能。     

核磁共振法(NMR)和pH法研究Zn(Ⅱ)与HEDP(1-羟基乙叉-1,1-二膦酸)的配合物

本文用核磁共振法(NMR)和pH法对Zn(Ⅱ)与1-羟基乙叉-1,1-二膦酸(1-hydroxyethylidenel,1-diphosphonic acid,简称HEDP,以H₄L表示)的配合物进行了研究,由于pH<7时溶液中有沉淀生成,故NMR的研究是在溶液pH>7时进行.测定了溶液中不同Zn(Ⅱ)/HEDP摩尔比和pH值时³¹PNMR的化学位移。研究结果表明在pH7.5-11.0范围内生成Zn(Ⅱ)/HEDP=1(摩尔比)组成的配合物,在pH11.8-12.3范围内生成Zn(Ⅱ)/HEDP=2(摩尔比)组成的配合物,分别用pH法和NMR法测定了上述组成配合物的稳定常数.结果如下: logK_[zn(HL)^-] logK_[znL^2-] logK_[zn2L] pH法 4.69 7.51 11.63 NMR法——6.88-7.19 12.44.     

Enhanced indoor radon concentration by using radon-rich well water in a Japanese wooden house in Fukuoka, Japan

Summary Radon measurements were carried out in a Japanese wooden house built on granitic geology, where radon-rich well water is used. Atmospheric radon concentrations were measured over one year with passive integrated radon monitors. The monitors were distributed at several locations in the house and were replaced every two months. In order to confirm the diurnal variation and heterogeneous distribution of radon, short-term measurements were carried out accordingly. Radon, its decay products and terrestrial gamma-radiations were measured in this survey. From the long-term measurement, the radon concentration in the house ranged from 14 to 184 Bq^. m^-3with an arithmetic mean of 45 Bq^. m^-3. A radon concentration of 184 Bq^. m^-3was observed in the bathroom in spring (March-May) though the radon level was normal in the living room and bedroom. In order to characterize the house, similar measurements were conducted in several surrounding houses. There was a significant difference in radon concentration between the investigated houses. There was a spatial distribution of the radon concentration and the highest value was found in the bathroom. Radon and its decay products concentrations varied with time, which increased from midnight to morning whereas they decreased during daytime. Although the radon concentration in tap water was 1 Bq^. l^-1, a high level of 353 Bq^. l^-1was found in the well water.While well water was being used, the indoor radon concentration near the bathroom increased rapidly with a maximum value of 964 Bq^. m^-3. It is clear that the use of well water enhanced the radon level around the bathroom.     

Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway

Splenectomy has been reported to improve liver fibrosis in patients with cirrhosis and hypersplenism. However, the mechanisms remain unclear. Tumor necrosis factor superfamily 14 (TNFSF14; also known as LIGHT) is highly expressed in the context of fibrosis and promotes disease progression in patients with fibrotic diseases such as pulmonary and skin fibrosis. Here, we determined whether splenectomy controls the production of LIGHT to improve liver fibrosis. Splenectomy reduced serum LIGHT levels in cirrhotic patients with hypersplenism and a ConA-induced liver fibrosis mouse model. Blocking LIGHT resulted in the downregulation of TGF-β1 in RAW264.7 cells. LIGHT treatment of RAW264.7 and JS1 cells in coculture regulated transforming growth factor-β1 (TGF-β1) expression through the activation of JNK signaling. Small interfering RNA-mediated silencing of lymphotoxin β receptor (LTβR) in macrophages resulted in pronounced decreases in the levels of fibrosis and αSMA in JS1 cells. These results indicated that LIGHT bound to LTβR and drove liver fibrosis in vitro. Blocking TGF-β1 abolished the effect of LIGHT in vitro. Furthermore, the administration of recombinant murine LIGHT protein-induced liver fibrosis with splenectomy, while blocking LIGHT without splenectomy improved liver fibrosis in vivo, revealing that the decrease in fibrosis following splenectomy was directly related to reduced levels of LIGHT. Thus, high levels of LIGHT derived from the spleen and hepatic macrophages activate JNK signaling and lead to increased TGF-β1 production in hepatic macrophages. Splenectomy attenuates liver fibrosis by decreasing the expression of LIGHT.Subject terms: Tumour-necrosis factors, Liver fibrosis, Hepatic stellate cells, Liver cirrhosis, Experimental models of disease