三类白细胞核孔筛滤试验的双参数模型

白细胞核孔筛滤试验是估计白细胞变形性的主要方法之一．我们对这一试验的三类情形提出了生物流体力学模型，这三类情形是：（i）自身重力过滤；（ii）恒压过滤；（iii）恒流量过滤．在以前的模型中，细胞阻力被假定为一常数，而在本文中，我们考虑细胞阻力时，同时顾及了驱动压力和白细胞个体变形性差异的影响．而且，我们在Moessmer实验基础上，对多形核粒性白细胞通过核孔的时间假定了一个概率分布函数．最后我们得到了以上三种情形的数值解，第一种情形的解与实验结果的对比是令人满意的．文中的双参数，A和B，代表了不同压力下白细胞变形性的不同．     

激光二极管泵浦腔内倍频Nd：YVO4／KTP绿光噪声研究

从实验上测量了Ｎｄ：ＹＶＯ４／ＫＴＰ腔内激光器绿光噪声和腔长、泵浦功率的变化关系，并从理论上进行了分析计算、，找出多纵模情况下影响绿光噪声大小的关键因素。理论计算与实验结果相一致。     

包头市青山区8～10岁儿童碘缺乏病甲状腺肿大率及尿碘监测分析

调查了内蒙古青山区８～１０岁儿童碘缺乏病甲状腺肿大率，结果表明，甲状腺肿大率为１９．６％，且以城乡结合部居住儿童为高，监测了其尿碘，尿碘水平１００μｇ／Ｌ以下者为１１．２％，其中５０μｇ／Ｌ者了有发现，据此情况，今后仍要强化防治工作。     

Core velocity distribution in swirling pipe flow

Zusammenfassung Der stationäre Zustand des Kernbereiches für die Wirbelbewegung einer reibungsbehafteten Flüssigkeit in einem Rohr kann durch Burgers Linienwirbel dargestellt werden, vorausgesetzt, dass die axiale Strömungskomponente mit der Richtung des abfallenden Drucks zusammenfällt. Der Bereich der Festkörperdrehung nimmt durch Verringerung des Druckgefälles zu, und der Kern kann bei Erreichen eines hinreichend grossen, der Strömung entgegengerichteten Druckgefälles zum Stillstand gebracht werden.     

A proteomic strategy for the identification of caspase-associating proteins

We report the efficient in vivo labelling of caspases expressed inside apoptotic HeLa cells using fluoromethyl ketone (fmk)-containing probes; preliminary results indicated that these probes may be used to identify caspase-associating proteins.     

Research into releasing inorganic phosphate and base from 5′-dTMP irradiated by a low energy ion beam

Research into radiation damage of nucleotide is an important area in radiation biology. In this paper, the yield of inorganic phosphate and base released from 5′-dTMP irradiated by a 30 keV N⁺ ion beam was investigated in several aspects. The effect of particle fluence on yield and the influence of treatment with 0.1 N NaOH was deduced. By analysis, it is known that the alkali treatment not only increases the yield of inorganic phosphate, but also damages and splits the base released from irradiated 5′-dTMP. When the irradiated samples are treated by 0.1 N NaOH immediately, the yield of inorganic phosphate is increased by a factor of 1.7 and the concentration of base decreased to half of the original value. But the yield of inorganic phosphate could be increased by a factor of 2.8 after 40 min of alkali treatment. On the other hand, when 5prime;-dTMP was irradiated by the ion beam, the G(Pi) obtained was above 0.44, higher than with γ-radiation.     

The series solution of the Marchenko equation

The convergence of a Neumann-series solution of the Marchenko equation in L ₂[x, ∞) is proved and an explicit expression of the series solution is given.     

Biocompatible Micelles Based on Comb‐like PEG Derivates: Formation,Characterization, and Photo‐responsiveness

A novel comb‐like derivative CPEG‐g‐DNQ was prepared by incorporating light responsive 2‐diazo‐1,2‐naphthoquinone (DNQ) groups into the structure of comb‐like poly(ethylene glycol) (CPEG). DLS and TEM results showed that CPEG‐g‐DNQ self‐assembled into spherical micelles with an average size of about 135 nm in water. Upon exposure to light, the micelles could be disrupted because of the conversion of hydrophobic DNQ to hydrophilic 3‐indenecarboylic acid. Additionally, hydrophobic coumarin 102 was successfully loaded into the micelles and photo‐induced ON‐OFF release was demonstrated by fluorescence spectroscopy. MTT assay revealed that the micelles are biocompatible. These photo‐responsive micelles might have great potential for controlled release of hydrophobic drugs.

     

油酰柠檬酸三乙酯的合成及红外光谱研究

以柠檬酸和乙醇为原料,在磷酸和苯磺酸混合催化剂作用下,加热回流,酯化生成柠檬酸三乙酯。以油酸与氯化亚砜为原料,通过酰化反应合成油酰氯。再使柠檬酸三乙酯与油酰氯在吡啶作用下,通过酰基化反应合成油酰柠檬酸三乙酯。采用红外光谱法对原料、中间体、产物进行了红外光谱测试,并进行了红外谱图的分析与比较,证明了各步产品为目的产物。根据原料、中间体、产物红外谱图中相应特征吸收峰的消失或是出现,证明了所选择的合成工艺路线是可行的。     

A method for extracting human gait series from accelerometer signals based on the ensemble empirical mode decomposition

In this paper,the ensemble empirical mode decomposition(EEMD) is applied to analyse accelerometer signals collected during normal human walking.First,the self-adaptive feature of EEMD is utilised to decompose the accelerometer signals,thus sifting out several intrinsic mode functions(IMFs) at disparate scales.Then,gait series can be extracted through peak detection from the eigen IMF that best represents gait rhythmicity.Compared with the method based on the empirical mode decomposition(EMD),the EEMD-based method has the following advantages:it remarkably improves the detection rate of peak values hidden in the original accelerometer signal,even when the signal is severely contaminated by the intermittent noises;this method effectively prevents the phenomenon of mode mixing found in the process of EMD.And a reasonable selection of parameters for the stop-filtering criteria can improve the calculation speed of the EEMD-based method.Meanwhile,the endpoint effect can be suppressed by using the auto regressive and moving average model to extend a short-time series in dual directions.The results suggest that EEMD is a powerful tool for extraction of gait rhythmicity and it also provides valuable clues for extracting eigen rhythm of other physiological signals.