新显色剂偶氮胂DBM与轻稀土元素的显色反应及应用

作为稀土显色剂,含不对称胂(膦)酸基的变色酸双偶氮衍生物优于对称的同类化合物。为了进一步提高稀土显色剂的灵敏度和选择性,在不对称变色酸双偶氮衍生物非胂酸基一侧的偶氮基对位上引入推电子基团,邻位引入卤素取代基,得到一系列新的不对称变色酸双偶氮衍生物。其一般结构为:     

二组分混合物的最小流化特性

分析且分混合物的３种混合／分离状态及在完全混合时发生连续相转变的极限组成。提出一修养国非等密度体系混合／分离状态的法则与确定混合物空隙率简易可行的随意松散堆积方法。     

1—苯乙酰基—4—芳酰基氨基硫脲的合成及其在碱催化下的环化反应

1-酰基-4-芳基氨基硫脲类化合物在碱性条件下环化为具有广泛生物活性的3-取代基-4-芳基-1,2,4-三唑啉-5-硫酮的反应报道甚多,但1,4-位都含羰基的酰氨基硫脲在碱性条件下环化反应迄今报道较少。我们曾研究了1-[5-(α-萘)-2H-四唑-2-乙酰基]-4-芳酰基氨基硫脲和1-(α-萘乙酰基)-4-芳酰基氨基硫脲在碱催化下环化为3-取代基-4-芳酰基-1,2,4-三唑啉-5-硫酮的反应,它们在低浓度下均有一定的生物活性。本文研究了1-苯乙酰基-4-芳酰基氨基硫脲1_(a～m)在1mol/L K_2CO_3溶液催化下的环化反应,得到环化产物3-苄基-4-芳酰基-1,2,     

Microwaves and cellular immunity. II. Immunostimulating effects of microwaves and naturally occurring antioxidant nutrients

The effect of 8.15-18 GHz (1 Hz within) microwave radiation at a power density of 1 microW/cm2 on the tumor necrosis factor (TNF) production and immune response was tested. A single 5 h whole-body exposure induced a significant increase in TNF production in peritoneal macrophages and splenic T cells. The mitogenic response in T lymphocytes increased after microwave exposure. The activation of cellular immunity was observed within 3 days after exposure. The diet containing lipid-soluble nutrients (beta-carotene, alpha-tocopherol and ubiquinone Q9) increased the activity of macrophages and T cells from irradiated mice. These results demonstrate that irradiation with low-power density microwaves stimulates the immune potential of macrophages and T cells, and the antioxidant treatment enhances the effect of microwaves, in particular at later terms, when the effect of irradiation is reduced.     

循环流化床(CFB)煤/焦气化反应的研究 Ⅰ.操作气速、固体循环速率对循环流化床气化反应的影响

报道了山西西山焦煤飞灰，在小型循环流化床气化反应器上，以二氧化碳为气化介质，在不同操作条件下（气速、固体循环速率）的气化反应。研究结果表明，ＣＯ出口浓度及碳转化率随着ＣＦＢ操作气速减小、固体颗粒循环速率的增加而增加。即在ＣＦＢ床中，提高气体、固体停留时间（床内固体颗粒浓度）有利于ＣＦＢ气化的进行。ＣＯ浓度及碳转化率沿床高的变化趋势与床内颗粒浓度分布一致。     

发射光谱法测定钢中微量钡

钡作为炼钢过程中的示踪元素,在钢中起到置换作用,其原理与炼钢中加铝、钙有相似之处,同时能起到与镁在钢中吸化碳化物晶化晶界作用。国标尚未制定出钢中微量钡的测定方法,本文采用发射光谱法,阴极条件下激发测定钢中微量钡,测定限达0.001％,此法已应用于钢中微量钡的测定。 1 试验部分 1.1 仪器与主要试剂 希尔格—E742型大型水晶棱镜摄谱仪 钡标准溶液:称取BaCl_2·2H_2O1.779g于烧杯中加热溶解,冷却后移入1L量瓶中,用二次水定容。此溶液钡浓度为1mg·ml~(-1)。用时稀释成含钡0.01mg·ml~(-1)的工作液。 其它试剂均采用高纯试剂     

Flow injection amperometric detection of ascorbic acid using a Prussian Blue film-modified electrode

The PB film-modified electrode was used as an amperometric detector for flow injection analysis of ascorbic acid. The modified electrode detector showed good sensitivity, stability and reproducibility. The calibration curve for ascorbic acid was linear over the concentration range from 5.0x10(-6) to 1.0x10(-3) mol l(-1) with a slope of 19.9 mA mol(-1) per litre and a correlation coefficient of 0.999. The detection limit of this method was 2.49x10(-6) mol l(-1). The relative standard deviation of six replicate injections of 2.5x10(-4) mol l(-1) ascorbic acid was 2.5%. The results obtained for ascorbic acid determination in pharmaceutical products are in good agreement with those obtained by using the procedure involving the reaction between triiodide and ascorbic acid.     

High-throughput ribozyme-based assays for detection of viral nucleic acids

Many reports have suggested that target-activated ribozymes hold potential value as detection reagents. We show that a "half"-ribozyme ligase is activated similarly by three unstructured oligoribonucleotides representing the major sequence variants of a hepatitis C virus 5'-untranslated region (5'-UTR) target and by a structured RNA corresponding to the entire 5'-UTR. Half-ribozyme ligation product was detected both in an ELISA-like assay and in an optical immunoassay through the use of hapten-carrying substrate RNAs. Both assay formats afford a limit of detection of approximately 1 x 10(6) HCV molecules (1.6 attomol, 330 fM), a sensitivity which compares favorably to that provided by standard immunoassays. These data suggest that target-activated ribozyme systems are a viable approach for the sensitive detection of viral nucleic acids using high-throughput platforms.     

有机硅及其改性聚合物膜用于有机溶剂水溶液的渗透汽化分离

采用室温固化硅橡胶及其它三种改性硅氧烷聚合物制成渗透汽化膜,分离丙酮(A),丁酮(B)、乙醇(E)及异丙醇(P)等有机物的水溶液。结果表明,随着透过温度提高、透量成指数关系增大,但对分离系数影响甚小。透量大小顺序为A>B>E>P,分离系数大小顺序为A>B>P>E,当膜材料中(CH_3)_2SiO链节含量由70%上升到100%时,有机物的透量及分离系数同时增加。