A Quinoxaline−Naphthaldehyde Conjugate for Colorimetric Determination of Copper Ion

This work facilitates detection of bivalent copper ion by a simple Schiff base probe QNH based on a quinoxaline−naphthaldehyde framework. The detailed study in absorption spectroscopy and theoretical aspects and crystal study of the probe and probe−copper complex has been discussed. The detection limit of the probe in the presence of Cu²⁺ is 0.45 µM in HEPES−buffer/acetonitrile (3/7, v/v) medium for absorption study. The reversibility of the probe−copper complex has been investigated by EDTA. The selective visual detection of copper has been established also in gel form.     

Introduction of Ferrocene as a Facilitator for the Construction of Supramolecular Polymers

Proper monomer design is the key to enhancing the strength of noncovalent interactions between the molecules toward the efficient formation of supramolecular polymers (SPs). We have designed and synthesized 1,n′-disubstituted ferrocene-azobenzene-long alkyl chains, Fc(CONH-Azo-TDP)₂, to afford SPs with a high probability. The design exploits the ‘‘molecular ball-bearing’’ property of the ferrocene core, which allows two azobenzene arms to rotate in the planes of cyclopentadienyl rings, generating the most suitable molecular conformation required for SP formation. This ferrocene monomer formed a supergel consisting of SPs supported by strong intermolecular (H-bonding and π-π stacking) interactions and higher enthalpy gain than the reference molecules, where the central ferrocene core was replaced by flexible aliphatic as well as rigid benzene linkers. The molecular conformation involved in SPs, the strength of noncovalent interactions, and the process of supramolecular polymerization were investigated through NMR, UV-Vis, XRD and TEM studies. The results demonstrate that ferrocene may act as a good modulator for constructing efficient SPs.