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Wannaporn DisadeeChulabhorn Mahidol Poolsak SahakitpichanSomkit Sitthimonchai Somsak Ruchirawat Tripetch Kanchanapoom 《Tetrahedron》2011,67(23):4221-4226
Six new flavonol 3-O-robinobiosides and 3-O-(2″-O-α-l-rhamnopyranosyl)-robinobiosides, sesuviosides A-F, were isolated from the aerial portion of Sesuvium portulacastrum together with ecdysterone, adenosine, 2′-O-methyladenosine, and l-tryptophan. The structure elucidations were based on analyses of chemical and spectroscopic data including 1D and 2D-NMR. Sesuviosides A-F and their aglycones exhibited radical scavenging activity using DPPH and ORAC assays. 相似文献
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Acharavadee Pansanit Nattha Ingavat Thammarat Aree Chulabhorn Mahidol Somsak Ruchirawat Prasat Kittakoop 《Tetrahedron letters》2012,53(16):2129-2131
Nitrones are formed from the reaction of aspergillusol A (1) and a ketone/aldehyde in phosphate buffer and aqueous solutions with pH ranges of 6.8–8.6, resembling physiological conditions. The reaction of 1 with 1-substituted cyclohexanones gave the (1′S1,2′R1)-isomer, diastereoselectively. 相似文献
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Athikomkulchai S Prawat H Thasana N Ruangrungsi N Ruchirawat S 《Chemical & pharmaceutical bulletin》2006,54(2):262-264
Two new compounds, 3'-(4'-hydroxy-3',5'-dimethoxyphenyl)-propyl benzoate (1) and 3'-(4'-hydroxyphenyl)-propyl benzoate (3) together with known compounds, 3'-(4'-hydroxy-3'-methoxyphenyl)-propyl benzoate (2), poilaneic acid (4), farnesyl acetone (5) and 4-hydroxybenzaldehyde (6) were isolated and identified from the branches of Croton hutchinsonianus. Their structures were determined by spectroscopic methods. The three phenylpropyl benzoates (1-3) were found to exhibit antifungal activity against Candida albicans (IC(50) 5.36-11.41 microg/ml). Compounds 1-2 (IC(50) 2.11-4.95 microg/ml) exhibited potent but non-selective activity against the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) whereas 3 (IC(50) 1.88 microg/ml) preferentially inhibited the enzyme COX-2. 相似文献
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