Simultaneous determination of cloramphenicol, salicylic acid and resorcinol by capillary zone electrophoresis and its application to pharmaceutical dosage forms

This study demonstrates the separation of active ingredients in acne formulations (salicylic acid, cloramphenicol and resorcinol in presence of azulene) by capillary zone electrophoresis. Factors affecting their separations were the buffer pH and concentration, applied voltage, sample preparation, and presence of additives. Optimun results were obtained with a 50 mM sodium tetraborate-50 mM sodium phosphate, pH 9.0. The carrier electrolyte gave baseline separation with good resolution, short migration times (<6 min), great reproducibility and accuracy. Calibration plots were linear over at least three orders of magnitude of analyte concentrations, the lower limits of detection being within the range 0.39-1.25 μg ml⁻¹. The procedure was fast and reliable and commercial pharmaceuticals could be analysed without prior sample clean-up procedure.     

On existence and asymptotic stability of solutions of a nonlinear integral equation

We prove an existence theorem for a nonlinear integral equation being a Volterra counterpart of an integral equation arising in the traffic theory. The method used in the proof allows us to obtain additional characterization in terms of asymptotic stability of solutions of an equation in question.     

The Orevkov invariant of an affine plane curve

We show that although the fundamental group of the complement of an algebraic affine plane curve is not easy to compute, it possesses a more accessible quotient, which we call the Orevkov invariant.

     

Comparison of Several Calibration Procedures for Glass Electrodes in Proton Concentration

Several reported procedures for calibrating glass electrodes in proton concentration are compared. Some recommendations for non-experts are also given. The examined procedures can be classified into two broad categories, namely: those based on direct potential difference measurements of solutions of known proton concentration and those that use one or several pH standards to calibrate the electrode and subsequently measure the pH of solutions containing known proton concentrations. With a single buffer, the two types of procedures lead to equivalent results. However, if two pH buffers are used, the slope of the calibration graph in proton concentration will differ from the real electrode slope to an extent proportional to the difference between the liquid junction potentials of the two buffers. Therefore, any other method is preferable under these circumstances.     

On the spectral picture of an irreducible subnormal operator II

In this paper we show that the spectral picture of an irreducible subnormal operator may be arbitrarily prescribed subject only to certain natural necessary conditions. This completes work begun by the second author.

     

Influence of mass moment of inertia on the normal modes of a preloaded solar array mast

Earth-orbiting spacecraft often contain solar arrays or antennas supported by a preloaded mast. Due to weight and cost considerations, the supporting structures of the spacecraft appendages are made extremely light and flexible. Therefore, it is essential to investigate the influence of all physical and structural parameters on the dynamic behavior of the overall structure. The governing equation of motion and its general solution for the preloaded mast are developed. Furthermore, the mass moment of inertia of the mast subjected to bending vibrations is included in the governing equation of motion to investigate its influence on determining the circular frequencies. To verify the developed formulations, a finite element technique was implemented. The accuracy and limitation of the technique on calculating the circular frequencies are discussed. Although the study described in this paper primarily focuses on the mast for the space station solar arrays, the developed formulations and techniques can be applied to any large and flexible beam in zero gravity.     

Invariant Subspaces for Semigroups of Algebraic Operators

T. Laffey showed (Linear and Multilinear Algebra6(1978), 269–305) that a semigroup of matrices is triangularizable if the ranks of all the commutators of elements of the semigroup are at most 1. Our main theorem is an extension of Hthis result to semigroups of algebraic operators on a Banach space. We also obtain a related theorem for a pair {A, B} of arbitrary bounded operators satisfying rank (AB−BA)=1 and several related conditions. In addition, it is shown that a semigroup of algebraically unipotent operators of bounded degree is triangularizable.