Microcantilevers as gas‐phase sensing platforms: Simplification and optimization of the production of polymer coated porous‐silicon‐over‐silicon microcantilevers

The asymmetric roughening of silicon microcantilevers using different vapor stain‐etching conditions is studied with the aim of optimizing face selective coating of microcantilevers by polymers through simple dipping. The effect of roughening is studied by following the time‐dependent guest‐induced bending of silicone microcantilevers coated with a poly‐4‐vinylpyridine sensing layer. A correlation between the surface roughness of the microcantilevers and their time‐dependent guest‐induced bending is gained from combining high resolution scanning electron microscopy studies of the surface of the microcantilevers as well as their cross‐sections with time‐dependent guest‐induced microcantilever bending. The purpose of the present work is to lay the foundations for a small and relatively simple gas‐phase sensing tool based on a microcantilever platform capable of offering wide range sensing capabilities. © 2013 Wiley Periodicals, 2014 , 52, 141–146     

Adaptive identification in graphs

An adaptive version of identifying codes is introduced. These codes are motivated by various engineering applications. Bounds on adaptive identifying codes are given for regular graphs and torii in the square grid. The new codes are compared to the classical non-adaptive case.     

“Cone-free” primal-dual path-following and potential-reduction polynomial time interior-point methods

We present a framework for designing and analyzing primal-dual interior-point methods for convex optimization. We assume that a self-concordant barrier for the convex domain of interest and the Legendre transformation of the barrier are both available to us. We directly apply the theory and techniques of interior-point methods to the given good formulation of the problem (as is, without a conic reformulation) using the very usual primal central path concept and a less usual version of a dual path concept. We show that many of the advantages of the primal-dual interior-point techniques are available to us in this framework and therefore, they are not intrinsically tied to the conic reformulation and the logarithmic homogeneity of the underlying barrier function.Part of the research was done while the author was a Visiting Professor at the University of Waterloo.Research of this author is supported in part by a PREA from Ontario and by a NSERC Discovery Grant. Tel: (519) 888-4567 ext.5598, Fax: (519) 725-5441Mathematics Subject Classification (2000): 90C51, 90C25, 65Y20,90C28, 49D49     

Engineered self-organization of neural networks using carbon nanotube clusters

A novel approach was developed to form engineered, electrically viable, neuronal networks, consisting of ganglion-like clusters of neurons. In the present method, the clusters are formed as the cells migrate on low affinity substrate towards high affinity, lithographically defined carbon nanotube templates on which they adhere and assemble. Subsequently, the gangliated neurons send neurites to form interconnected networks with pre-designed geometry and graph connectivity. This process is distinct from previously reported formation of clusterized neural networks in which a network of linked neurons collapses via neuronal migration along the inter-neuron links. The template preparation method is based on photo-lithography, micro-contact printing and carbon nanotube chemical vapor deposition techniques. The present work provides a new approach to form complex, engineered, interconnected neuronal network with pre-designed geometry via engineering the self-assembly process of neurons.     

The rheologic properties of erythrocytes: a study using an automated rheoscope

Red blood cells (RBCs) suspended in a high-viscosity medium were filmed while flowing through a microchannel using an automated rheoscope. Under these conditions, erythrocytes take different orientations and undergo varying deformation according to their location in the velocity profile. Measurements of the mean deformation at several distances from the center of the microchannel at a constant flow rate were acquired for normal and thalassemia erythrocytes. The measurements demonstrate how diagnosis can be made based on a single flow rate in contrast to conventional methods where shear is mechanically controlled. The spatial distribution and velocity of RBCs and rigid microspheres (1 μm) were measured. The maximum slip velocity was found to be linearly correlated to the flow rate for both cells and microspheres. RBCs showed enhanced inward lateral migration compared to the rigid spheres, which is attributed to RBC deformation. The results demonstrate the coupling between RBC mechanical properties and their motion in microvessels. This paper was presented at Annual European Rheology Conference (AERC) held in Hersonisos, Crete, Greece, April 27-29, 2006.     

Structure of gum arabic in aqueous solution

Gum arabic, a natural polysaccharide derived from exudates of Acacia senegal and Acacia seyal trees, is a commonly used food hydrocolloid. The complex chemical structure of the gum has been widely studied revealing a multifraction material consisting mainly of a highly branched polysaccharide and a protein–polysaccharide complex (GAGP) as a minor component. This work investigates its mesoscopic structure in aqueous solution by small‐angle X‐ray and neutron scattering combined with cryotransmission electrons microscopy. Scattering measurements reveal an intricate shape composed of many spheroidal aggregates assigned to the polysaccharide with a small amount of larger coils. A scattering peak is observed at moderate to high concentrations, the spacing of which exhibits a c^?1/3 power law relation to polymer concentration (c). Upon addition of salt, this peak disappears, indicating its electrostatic nature. The large coils contribute a q^?2 power law at the low scattering vector (q) range. However, at low concentration in which the interaggregate peak is not observed, a q^?1 power law at the low q range indicates the possible existence of a fraction with a locally extended conformation. © 2006 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 44: 3265–3271, 2006     

Extending Scope of Robust Optimization: Comprehensive Robust Counterparts of Uncertain Problems

In this paper, we propose a new methodology for handling optimization problems with uncertain data. With the usual Robust Optimization paradigm, one looks for the decisions ensuring a required performance for all realizations of the data from a given bounded uncertainty set, whereas with the proposed approach, we require also a controlled deterioration in performance when the data is outside the uncertainty set. The extension of Robust Optimization methodology developed in this paper opens up new possibilities to solve efficiently multi-stage finite-horizon uncertain optimization problems, in particular, to analyze and to synthesize linear controllers for discrete time dynamical systems. Research was supported by the Binational Science Foundation grant #2002038     

Plasticization of a polymer layer harnessed to a silicon microcantilever as a highly sensitive and selective means to detect nitroaromatic derivatives

A new approach to the chemo‐mechanical detection of trace amounts of nitroaromatics, even in the presence of high concentrations of background materials, is presented. The detection scheme is based on the plasticization of an aminopropyl silane layer that is harnessed to a silicon beam following its reaction with nitroaromatic systems. The reaction‐induced plasticization attenuates the temperature induced bending of the polymer‐beam sandwich, offering a simple and very sensitive tool for the detection of nitroaromatic systems. Using this approach, it was possible to detect a sample of 100 pg TNT even in the presence of a ～10⁹ fold excess of a background material such as acetonitrile. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014 , 52, 2124–2130     

Sensitive and selective PET-based diimidazole luminophore for Zn(II) ions: a structure-activity correlation

3-(3-Ethoxymethyl-1H-imidazol-2-yl)-3-(1-ethoxymethyl-1H-imidazol-2-yl)-3H-benzo[de]isochromen-1-one, 4, is a novel photoinduced electron transfer (PET) chemosensor that becomes fluorescent upon binding metal ions and shows a strong preference toward Zn(II) ions. The new bisimidazol PET sensor and its zinc complex were prepared and characterized in terms of their crystal structures, absorption and emission spectra, and orbital energy diagrams. Free 4 is a weakly luminescent species. On the basis of detailed DFT calculations, we suggest that the poor luminescence yield of free 4 originates from its orbital structure in which two pi-orbitals of the two imidazole rings, HOMO and HOMO-1, are situated between two pi-orbitals of the isochromene-one system, HOMO-2 and LUMO. The absorption and emission processes occur between the two pi-orbitals of the isochromene-one system, HOMO-2 and LUMO, and the two pi-imidazole orbitals serve as quenchers for the excited state of the molecule through nonradiative processes. Upon binding Zn(II) ions, 4 becomes a highly luminescent species having a luminescence maximum peaking at 375 nm (lambda(ex) = 329 nm). The significant 900-fold enhancement in luminescence upon binding of the Zn(II) ions is attributed to the stabilization of the pi-orbitals of the imidazole rings upon their engagement in new bonds with the zinc ion. The affinity of 4 to zinc ions in acetonitrile is found to be very high, Ka > 3 x 10(6) M(-1), while with other metals ions, the association constants are considerably weaker.     

Structure of algal-born phenolic polymeric adhesives

Adhesive materials extracted from the brown alga Fucus serratus are composed of phenolic polymer, alginate, and CaCl2. The phenolic polymer undergoes an oxidation reaction in the presence of bromoperoxidase, KI, and H2O2. The nanostructure of the adhesive was investigated using small angle X-ray scattering, light scattering, and cryo- transmission electron microscopy experiments. These have shown that the phenolic polymer undergoes self-assembly and forms flexible chain-like objects. Oxidation or adding alginate does not alter this structure. However, once calcium ions are added, a rigid network is formed. Presumably, this network is responsible for the cohesive strength of the glue.