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Bernhard Beckermann Daniel Bessis Luca Perotti Daniel Vrinceanu 《Numerical Algorithms》2012,61(2):189-208
We describe a new method of computing matrix Padé approximants of series with integer data in an efficient and fraction-free way, by controlling the growth of the size of intermediate coefficients. This algorithm is applied to compute high precision Padé approximants of matrix-valued generating functions of time series. As an illustration we show that we can successfully recover from noisy equidistant sampling data a joint damped signal of four antenna, even in the presence of background signals. 相似文献
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Luca Fabrizio Di Cerbo 《Annals of Global Analysis and Geometry》2012,41(3):371-380
We derive an obstruction to the existence of cuspidal Einstein metrics on finite-volume complex surfaces. This generalizes
a theorem of LeBrun for compact complex surfaces. As in the compact case, such a result relies on a scalar curvature estimate.
Finally, the obstruction is made explicit on some examples. 相似文献
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Coronary artery diseases are a leading cause of mortality and are increasingly prevalent with age. However, the large number of age-increasing co-morbidities make difficult to understand the impact of cardiovascular ageing alone on the coronary flow pattern. The present study aims to shed light on the effect of arterial and ventricular ageing on the coronary circulation, which is here studied by means of a validated mathematical model. Forward and backward pressure and flow waves are analysed, as well as their intensity. Results highlight a complex spatiotemporal coronary wave pattern, where intense waves originate from the aorta (particularly in systole) and from the deep myocardium, during both the isovolumic compression and the diastolic phase. The subendocardial viability ratio decreases with age, the total coronary flow is slightly reduced, and the left-ventricular work increases. Consequently, the left-ventricular work per unit of blood flow increases, thus limiting the cell oxygen availability abundance, and therefore increasing the risk of myocardial infarction. Our results highlight a physiological age-induced supply/demand unbalance, which can augment the risk of myocardial ischemia and can contribute to pave the way to other typical coronary pathological processes. 相似文献
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Bianca Flavia Bonini Luca Bernardi Mauro Comes-Franchini Gabriella Dessole Mariafrancesca Fochi Alfredo Ricci 《Phosphorus, sulfur, and silicon and the related elements》2013,188(5-6):1273-1277
Abstract Enantiomerically pure 2-hydroxyalkyl, 2-aminoalkyl and 2-iminoalkyl ferrocenyl p-tolylsulfides are easily prepared in good yields and with complete diastereocontrol from (S)-(2-p-tolylthio)ferrocencarboxyaldehyde. 2-Iminoalkyl ferrocenyl derivatives can be used as ligands in asymmetric catalysis and as starting materials for asymmetric Staudinger reaction. 相似文献
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Marco Cespi Luca Casettari Giulia Bonacucina Gianfabio Giorgioni Diego R Perinelli Giovanni Filippo Palmieri 《先进技术聚合物》2013,24(11):1018-1024
This paper deals with a new application of diblock methoxy polyethylene glycol‐polylactide block copolymers, a class of synthetic biomaterials largely studied in the pharmaceutical and biomedical fields owing to their favorable properties such as biocompatibility, biodegradability, low immunogenicity, and good mechanical properties. In this work, these materials were evaluated as additives for gastro‐soluble pharmaceutical coating aimed to reduce film stiffness and water permeability. Two copolymers with different polylactide chain lengths were synthesized and characterized in term of molecular weight and solid‐state properties. A series of free films with different hypromellose/copolymers ratio were prepared and characterized in terms of appearance, components miscibility, plasticity, and water vapor permeability. The obtained results demonstrate that copolymers effectively influence hypromellose film properties according to their concentration and molecular weight. Specifically, the addition of the copolymer with a molecular weight of 6.5 kDa in a ratio hypromellose:polymer 5:1, allowed to obtain films with good appearance, improved plasticization, and water permeability properties. For higher molecular weight, copolymer or different ratios was not possible to observe the improvement of all the properties at the same time. The results also make possible to define the critical features to improve in order to use block copolymers as additive in hypromellose film coating. The availability of new water‐soluble additives able to work as plasticizer and moisture sealer in polymeric films represents an important progress not only in the field of pharmaceutical coating but also in that of food coatings, as for example in the formulation of edible films. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献