MRI of the temporal lobe: normal variations, with special reference toward epilepsy.

Recent investigations of epilepsy, Alzheimer's disease, amnesia, and schizophrenia have used magnetic resonance imaging (MRI) to evaluate changes in temporal lobe structures. Normal variations in these structures need to be defined before one can use these structures to describe abnormal conditions. Twenty-nine normal volunteers were studied by coronal MRI. Frequent findings include notching of the uncus by the tentorium or adjacent vessels (22/29) and asymmetry of the temporal horns (20/29). This finding of uncal notching strengthens the evidence against "incisural sclerosis" as the basis for hippocampal sclerosis. Temporal horn dilatation occurred in four. However, mild asymmetry of the temporal horn was seen frequently at its anterior tip (16/29) and may be related to head rotation. Asymmetry of the choroidal fissure was never marked. Mild asymmetry was common at the hippocampal head (pes). Mild enlargement of the right temporal lobe by visual inspection is not uncommon. Subtle asymmetry of the white matter between the hippocampus and the collateral sulcus occurred in six. The collateral sulcus does not always point to the temporal horn. The occipitotemporal sulcus may point to the temporal horn. Asymmetric uncal protrusion (0/29) and Sylvian fissure dilatation (4/29) occur rarely.     

The CST bounce universe model——A parametric study

A bounce universe model with a scale-invariant and stable spectrum of primordial density perturbations was constructed using a consistent truncation of the D-brane dynamics from Type IIB string theory. A coupling was introduced between the tachyon field and the adjoint Higgs field on the D3-branes to lock the tachyon at the top of its potential hill and to model the bounce process,which is known as the Coupled Scalar and Tachyon Bounce(CSTB) Universe. The CSTB model has been shown to be ghost free,and it fulfils the null energy condition; in addition, it can also solve the Big Bang cosmic singularity problem. In this paper we conduct an extensive follow-up study of the parameter space of the CSTB model. In particular we are interested in the parameter values that can produce a single bounce to arrive at a radiation-dominated universe. We further establish that the CSTB universe is a viable alternative to inflation, as it can naturally produce a sufficient number of e-foldings in the locked inflation epoch and in the post-bounce expansion to overcome the four fundamental limitations of the Big Bang cosmology, which are flatness, horizon,homogeneity and singularity, resulting in a universe of the current size.     

Synthesis of multiple boron-containing analogs via Ugi-4CR

Research on Chemical Intermediates - One of the most significant challenges in boron neutron capture therapy (BNCT) is to have an ideal boron delivery agent which can deliver sufficient numbers of...     

Optimization of a hybrid vibration absorber for vibration control of structures under random force excitation

A recently reported design of a hybrid vibration absorber (HVA) which is optimized to suppress resonant vibration of a single degree-of-freedom (SDOF) system is re-optimized for suppressing wide frequency band vibration of the SDOF system under stationary random force excitation. The proposed HVA makes use of the feedback signals from the displacement and velocity of the absorber mass for minimizing the vibration response of the dynamic structure based on the H₂ optimization criterion. The objective of the optimal design is to minimize the mean square vibration amplitude of a dynamic structure under a wideband excitation, i.e., the total area under the vibration response spectrum is minimized in this criterion. One of the inherent limitations of the traditional passive vibration absorber is that its vibration suppression is low if the mass ratio between the absorber mass and the mass of the primary structure is low. The active element of the proposed HVA helps further reduce the vibration of the controlled structure and it can provide significant vibration absorption performance even at a low mass ratio. Both the passive and active elements are optimized together for the minimization of the mean square vibration amplitude of the primary system. The proposed HVA are tested on a SDOF system and continuous vibrating structures with comparisons to the traditional passive vibration absorber.     

A tandem Heck-carbocyclization/Suzuki-coupling approach to the stereoselective syntheses of asymmetric 3,3-(diarylmethylene)indolinones

[reaction: see text] An efficient and versatile method for stereoselective synthesis of (E)-3,3-(diarylmethylene)indolinones by a palladium-catalyzed tandem Heck-carbocyclization/Suzuki-coupling sequence is presented. Factors influencing yield and selectivity, namely catalyst, coordinating ligand, and solvent, are detailed.     

On the blow-up of heat flow for conformal -harmonic maps

Using a comparison theorem, Chang, Ding, and Ye (1992) proved a finite time derivative blow-up for the heat flow of harmonic maps from (a unit ball in ) to (a unit sphere in ) under certain initial and boundary conditions. We generalize this result to the case of -harmonic map heat flow from to . In contrast to the previous case, our governing parabolic equation is quasilinear and degenerate. Technical issues such as the development of a new comparison theorem have to be resolved.

     

Experimental study of the radiative decays K+-->mu(+)nue(+)e(-) and K+-->e(+)nue(+)e(-)

Experiment 865 at the Brookhaven Alternating Gradient Synchrotron obtained 410 K+-->e(+)nue(+)e(-) and 2679 K+-->mu(+)nue(+)e(-) events including 10% and 19% background. The branching ratios were measured to be [2.48+/-0.14(stat)+/-0.14(syst)]x10(-8) (m(ee)>150 MeV) and (7.06+/-0.16+/-0.26)x10(-8) (m(ee)>145 MeV), respectively. Results for the decay form factors are presented.     

Relationship of hippocampus and amygdala to coronal MRI landmarks

Magnetic resonance imaging is playing an increasingly important role in the evaluation of the hippocampus, particularly in epilepsy, schizophrenia, and Alzheimer's dementia. Because of the complex configuration of the hippocampus, it is difficult to compare from patient to patient. We developed a system to allow comparison of the hippocampus on coronal images. We performed 34 magnetic resonance studies on 29 normal subjects. Ten anatomic landmarks were identified. These landmarks have a consistent 5-mm periodicity regardless of usual head flexion. In the second phase of our investigation, we showed that the amygdala, hippocampal head, hippocampal body, and hippocampal tail have a consistent relationship to the coronal magnetic resonance imaging landmarks.