Intranasal irradiation with the xenon chloride ultraviolet B laser improves allergic rhinitis

We earlier reported that the 308 nm xenon chloride (XeCl) ultraviolet B (UVB) laser is highly effective for the treatment of inflammatory skin diseases. Since UVB irradiation has been shown to exert both local and systemic immunosuppression, we investigated the clinical efficacy of UVB irradiation in allergic rhinitis. In an open study, groups of patients with severe allergic rhinitis received intranasal irradiation with a 308 nm XeCl UVB excimer laser for two weeks. In the low-dose group (n=10), treatment was given twice weekly, starting with 0.25x the individual minimal erythema dose (MED), whereas patients in the medium-dose group (n=8) were treated four times weekly, starting with 0.4x MED. In each group, the dosage was gradually increased. Evaluation was based on the symptom scores. The effect of the XeCl laser on the skin prick test reaction was also studied. In the low-dose group, seven patients completed the study, and there was no improvement in the nasal symptoms. In the medium-dose group, the XeCl UVB irradiation significantly inhibited the rhinorrhoea, the sneezing, the nasal obstruction and the total nasal score (p<0.05). The XeCl UVB excimer laser also inhibited the allergen-induced skin prick test in a dose-dependent manner. These results suggest that the XeCl UVB excimer laser might serve as a new therapeutic tool in the treatment of allergic rhinitis.     

The German bakery waste incident; use of a combined approach of screening and confirmation for dioxins in feed and food

During the last six years several incidents have occurred with dioxins in feed, stressing the need for rapid screening methods for these compounds. The most recent incident was the contamination of bakery waste used for animal feed due to the use of waste wood for drying of the material. In addition to Germany, the material was also shipped to the Netherlands. Levels up to 12 ng TEQ/kg have been detected, being about 15 times over the current limit of 0.75 ng TEQ/kg. In the Netherlands a combined strategy of screening with the CALUX-bioassay and the HRGC/HRMS confirmatory method was used to rapidly control the incident. Pigs were contaminated by the incident but only to a very limited extent. Despite the rather low limits for pig meat, the CALUX bioassay showed excellent performance, once again confirming the value of this assay.     

On Some Three-Color Ramsey Numbers

 In this paper we study three-color Ramsey numbers. Let K _i,j denote a complete i by j bipartite graph. We shall show that (i) for any connected graphs G ₁, G ₂ and G ₃, if r(G ₁, G ₂)≥s(G ₃), then r(G ₁, G ₂, G ₃)≥(r(G ₁, G ₂)−1)(χ(G ₃)−1)+s(G ₃), where s(G ₃) is the chromatic surplus of G ₃; (ii) (k+m−2)(n−1)+1≤r(K _1,k , K _1,m , K _n )≤ (k+m−1)(n−1)+1, and if k or m is odd, the second inequality becomes an equality; (iii) for any fixed m≥k≥2, there is a constant c such that r(K _k,m , K _k,m , K _n )≤c(n/logn), and r(C _2m , C _2m , K _n )≤c(n/logn) ^m/(m−1) for sufficiently large n. Received: July 25, 2000 Final version received: July 30, 2002 RID="*" ID="*" Partially supported by RGC, Hong Kong; FRG, Hong Kong Baptist University; and by NSFC, the scientific foundations of education ministry of China, and the foundations of Jiangsu Province Acknowledgments. The authors are grateful to the referee for his valuable comments. AMS 2000 MSC: 05C55     

104 nm period grating fabrication in fused silica by immersion two-beam interferometric laser induced backside wet etching technique

A substantial extension of the method of two-beam interferometric laser induced backside wet etching (TWIN-LIBWE), the immersion TWIN-LIBWE, is used to fabricate fused silica gratings with a 104 nm period. The spatially filtered fourth harmonic of Nd:YAG laser (λ=266 nm, τ_FWHM=8 ns) pulses were split into two parts which then interfered at the backside of the fused silica target in contact with a liquid absorber (naphthalene methyl methacrylate saturated solution with a concentration of 1.85 mol/dm³). The hypotenuse of a rectangular fused silica prism is attached to the fused silica target with the use of distilled water as the immersion liquid. On steering the beams through the sides of the prisms, the angle between the two laser beams has been substantially increased. The resulting period of 104 nm is the minimal grating constant achievable under such experimental conditions and, to our knowledge, the smallest laser generated grating period in fused silica at present. PACS 42.62; 42.79; 81.65     

Dynamic stability of rotor-bearing systems subjected to random axial forces

This paper investigates the lateral vibration of a spinning disk-shaft system supported by a pair of ball bearings and subjected to a pair of random axial forces at both ends. The axial forces are assumed as the sum of a static force and a random process with a zero mean. Due to the random axial forces, the rotor-bearing system may experience parametric random instability under certain situations. In this work, the finite element method is applied to yield a set of discretized system equations first. The set of discretized system equations is partially uncoupled by the modal analysis procedure suitable for gyroscopic systems. The stochastic averaging method is then adopted to obtain Ito's equations for the response amplitudes of the system. Finally the first- and second-moment stability criteria are utilized to determine the stability boundaries of the system. Numerical results show that the rotor-bearing system is always stable in the sense of the first-moment stability, and the effects of the average axial compressive force and the disk mass, which will lower all frequencies of the system, tend to destabilize the second-moment stability of the system.     

Laser-induced periodic surface structures on different poly-carbonate films

Laser-induced periodic surface structures (LIPSS) were generated on oriented and amorphous thick, as well as on spin-coated thin, poly-carbonate films by polarized ArF excimer laser light. The influence of the film structure and thickness on the LIPSS formation was demonstrated. Below a critical thickness of the spin-coated films the line-shaped structures transformed into droplets. This droplet formation was explained by the laser-induced melting across the whole film thickness and subsequent de-wetting on the substrate. The thickness of the layer melted by laser illumination was computed by a heat-conduction model. Very good agreement with the critical thickness for spin-coated films was found. The original polymer film structure influences the index of refraction of the thin upper layer modified by the laser treatment, as was proven by the dependence of the structure’s period on the angle of incidence both for ‘s’- and ‘p’-polarized beams. The effect of the original surface roughness – grains in thick films or holes in thin films – was studied using atomic force microscopy. It was shown that the oblique incidence of ‘s’-polarized beams results in an intensity confinement in the direction of the forward scattering and in asymmetrical interference pattern formation around these irregularities. A new, two-dimensional grating-like structure was generated on spin-coated films. These gratings might be used as a special kind of mask. Received: 10 July 2001 / Accepted: 23 July 2001 / Published online: 30 August 2001     

Travelling-wave amplified spontaneous emission excited in a prismatic geometry

A new experimental realisation of the travelling-wave amplified spontaneous emission (TWASE) is described utilising a prismatic arrangement to get the pulse front delay in the pump beam. Rhodamine dye solutions were pumped by the amplified 25 ps long 555 nm pulses of a distributed feedback dye laser. The pulse shortening in the TWASE resulted in 12 ps output pulses with 18% energy efficiency. The observed spectrum showed numerous lines, and it contained the amplified Raman line of the pump beam. Several spots were found in the far-field zone of the generated TWASE.     

Dye laser pulse shortening and stabilization by Q-switching

The properties of passive Q-switched short-cavity dye lasers (SCDL) and passive Q-switched distributed-feedback dye lasers (DFDL) are investigated theoretically by using rate-equation models. The calculations, in agreement with experimental results, predict a significant decrease of the pulse energy fluctuation and the pulse duration of both the SCDL and DFDL, when passive Q-switching is used.     

A study on generalized quasi-power increasing sequences

In the present paper, we have proved a general theorem dealing with an application of quasi (β-σ)-power increasing sequences. This theorem also includes several new results.