全文获取类型
收费全文 | 104篇 |
免费 | 2篇 |
专业分类
化学 | 65篇 |
力学 | 2篇 |
数学 | 24篇 |
物理学 | 15篇 |
出版年
2019年 | 2篇 |
2018年 | 1篇 |
2016年 | 3篇 |
2015年 | 2篇 |
2014年 | 2篇 |
2013年 | 3篇 |
2012年 | 1篇 |
2011年 | 2篇 |
2010年 | 5篇 |
2009年 | 4篇 |
2008年 | 1篇 |
2007年 | 2篇 |
2006年 | 6篇 |
2005年 | 8篇 |
2004年 | 4篇 |
2003年 | 2篇 |
2002年 | 1篇 |
2001年 | 4篇 |
1999年 | 3篇 |
1998年 | 1篇 |
1997年 | 2篇 |
1996年 | 6篇 |
1995年 | 9篇 |
1994年 | 1篇 |
1993年 | 3篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 4篇 |
1980年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1972年 | 2篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1968年 | 2篇 |
1967年 | 1篇 |
1931年 | 1篇 |
1897年 | 1篇 |
排序方式: 共有106条查询结果,搜索用时 15 毫秒
1.
2.
Lopez-Martens A Hannachi F Dossing T Schück C Collatz R Gueorguieva E Vieu C Leoni S Herskind B Khoo TL Lauritsen T Ahmad I Blumenthal DJ Carpenter MP Gassmann D Janssens RV Nisius D Korichi A Bourgeois C Astier A Ducroux L Le Coz Y Meyer M Redon N Sharpey-Schafer JF Wilson AN Korten W Bracco A Lucas R 《Physical review letters》1996,77(9):1707-1710
3.
Information
Congresses, Conferences, Symposia, Meetings, and Seminars in the Field of Chemical Sciences held in 1995–1996 相似文献4.
5.
Mecke A Majoros IJ Patri AK Baker JR Holl MM Orr BG 《Langmuir : the ACS journal of surfaces and colloids》2005,21(23):10348-10354
Polycationic polymers are used extensively in biology to disrupt cell membranes and thus enhance the transport of materials into the cell. The highly polydisperse nature of many of these materials makes obtaining a mechanistic understanding of the disruption processes difficult. To design an effective mechanistic study, a monodisperse class of polycationic polymers, poly(amidoamine) (PAMAM) dendrimers, has been studied in the context of supported dimyristoylphosphatidylcholine (DMPC) lipid bilayers using atomic force microscopy (AFM). Aqueous solutions of amine-terminated generation 7 (G7) PAMAM dendrimers caused the formation of 15-40-nm-diameter holes in lipid bilayers. This effect was significantly reduced for smaller G5 dendrimers. For G3, no hole formation was observed. In addition to dendrimer size, surface chemistry had a strong influence on dendrimer-lipid bilayer interactions. In particular, acetamide-terminated G5 did not cause hole formation in bilayers. In all instances, the edges of bilayer defects proved to be points of highest dendrimer activity. A proposed mechanism for the removal of lipids by dendrimers involves the formation of dendrimer-filled lipid vesicles. By considering the thermodynamics, interaction free energy, and geometry of these self-assembled vesicles, a model that explains the influence of polymer particle size and surface chemistry on the interactions with lipid membranes was developed. These results are of general significance for understanding the physical and chemical properties of polycationic polymer interactions with membranes that lead to the transport of materials across cell membranes. 相似文献
6.
Information
Congresses, conferences, symposia, meetings, and seminars in the field of chemical sciences held in 1995–1996 相似文献7.
Structural Polymorphism and Thin Film Transistor Behavior in the Fullerene Framework Molecule 5,6;11,12‐di‐o‐Phenylenetetracene 下载免费PDF全文
Dipl.‐Ing. Tobias Wombacher Dr. Andrea Gassmann Sabine Foro Prof. Heinz von Seggern Prof. Dr. Jörg J. Schneider 《Angewandte Chemie (International ed. in English)》2016,55(20):6041-6046
The molecular structure of the hydrocarbon 5,6;11,12‐di‐o‐phenylenetetracene (DOPT), its material characterization and evaluation of electronic properties is reported for the first time. A single‐crystal X‐ray study reveals two different motifs of intramolecular overlap with herringbone‐type arrangement displaying either face‐to‐edge or co‐facial face‐to‐face packing depicting intensive π–π interactions. Density functional theory (DFT) calculations underpin that a favorable electronic transport mechanism occurs by a charge hopping process due to a π‐bond overlap in the DOPT polymorph with co‐facial arene orientation. The performance of polycrystalline DOPT films as active organic semiconducting layer in a state‐of‐the‐art organic field effect transistor (OFET) device was evaluated and proves to be film thickness dependent. For 40 nm layer thickness it displays a saturation hole mobility (μhole) of up to 0.01 cm2 V?1 s?1 and an on/off‐ratio (Ion/Ioff) of 1.5×103. 相似文献
8.
Hessler JA Budor A Putchakayala K Mecke A Rieger D Banaszak Holl MM Orr BG Bielinska A Beals J Baker J 《Langmuir : the ACS journal of surfaces and colloids》2005,21(20):9280-9286
Apoptosis is defined by a distinct set of morphological changes observed during cell death including loss of focal adhesions, the formation of cell membrane buds or blebs, and a decrease in total cell volume. Recent studies suggest that these dramatic morphological changes, particularly apoptotic volume decrease (AVD), are an early prerequisite to apoptosis and precede key biochemical time-points. Here we use atomic force microscopy to observe early stage AVD of KB cells undergoing staurosporine-induced apoptosis. After a 3-h exposure to 1 microM staurosporine, a 32% decrease in total cell height and a 50% loss of total cell volume is observed accompanied by only a 15% change in cell diameter. The observed AVD precedes key biochemical hallmarks of apoptosis such as loss of mitochondrial membrane potential, phosphatidyl serine translocation, nuclear fragmentation, and measurable caspase-3 activity. This suggests that morphological volume changes occur very early in the induction of apoptosis. 相似文献
9.
10.
Capillary zone electrophoresis is applied to investigate the recombinant insulin-like growth factor and recombinant hirudin. During the production of these peptides in S. cerevisiae, byproducts with small variations in the structure of the polypeptide chain are obtained. The different peptides are separated in a fused silica capillary and detected on-column by ultraviolet absorption or fluorescence. Separation times are 10–40 min. The excellent separation efficiencies obtained indicate that capillary zone electrophoresis is complementary to liquid chromatography in the analysis of these peptides. 相似文献