Micromechanical tunable vertical-cavity surface-emitting lasers

We report the study on a short wavelength-tunable vertical-cavity surface-emitting laser utilizing a monolithically integrated bridge tuning microelectromechanical system. A deformable-bridge top mirror suspended above an active region is utilized. Applied bridge-substrate bias produces an electrostatic force which reduces the spacing of air-gap and tunes the resonant wavelength toward a shorter wavelength (blue-shift). Good laser characteristics are obtained: such as continuous tuning ranges over 11 nm near 940 nm for 0--9 V tuning bias, the peak output power near 1 mW and the full-width-half-maximum limited to approximately 3.2--6.8 nm. A detailed simulation of the micromechanical and optical characteristics of these devices is performed, and the ratio of bridge displacement to wavelength shift has been found to be 3:1.     

Study on shock wave-induced cavitation bubbles dissolution process

This study investigated dissolution processes of cavitation bubbles generated during in vivo shock wave(SW)-induced treatments. Both active cavitation detection(ACD) and the B-mode imaging technique were applied to measure the dissolution procedure of bi Spheres contrast agent bubbles by in vitro experiments. Besides, the simulation of SW-induced cavitation bubbles dissolution behaviors detected by the B-mode imaging system during in vivo SW treatments, including extracorporeal shock wave lithotripsy(ESWL) and extracorporeal shock wave therapy(ESWT), were carried out based on calculating the integrated scattering cross-section of dissolving gas bubbles with employing gas bubble dissolution equations and Gaussian bubble size distribution. The results showed that(i) B-mode imaging technology is an effective tool to monitor the temporal evolution of cavitation bubbles dissolution procedures after the SW pulses ceased, which is important for evaluation and controlling the cavitation activity generated during subsequent SW treatments within a treatment period;(ii) the characteristics of the bubbles, such as the bubble size distribution and gas diffusion, can be estimated by simulating the experimental data properly.     

“一定溶质质量分数的氯化钠溶液的配制”项目式教学*——自制洗鼻液

以“盐水洗鼻”中洗鼻液的配制为抓手和主要任务,通过学生将任务拆解成子任务并转化为化学问题,在合作探究、实际操作中,掌握溶质、溶剂及溶质质量分数之间的关系,配制出符合标准的洗鼻液。     

包膜黏弹特性及声驱动参数对相互作用微泡动力学行为的影响

关于多气泡相互作用的理论研究对于深入理解超声造影剂在医疗领域中的应用机理具有重要意义。本工作建立了一个2维轴对称有限元模型来研究流体环境中超声造影剂双气泡相互作用,讨论了驱动超声频率和气泡尺寸对气泡之间吸引和排斥趋势的影响,得到了气泡半径与气泡之间距离随时间变化的曲线,以及气泡周围流体速度场的细节,并且研究了气泡包膜参数(即表面张力系数和粘度系数)对气泡相互作用的影响.结果表明,相互作用中的气泡对整体的相对运动趋势由驱动频率和共振频率之间的关系决定;在超声参数固定时,气泡包膜的粘弹特性可用来调控气泡间相互作用强度。结果对实验中观察到的气泡聚集现象进行了合理解释,并为超声造影剂在医疗实践中的应用提供了基础理论支撑.     

水产品中喹烯酮和喹赛多及其主要代谢物残留的HPLC-MS/MS检测方法研究

以草鱼、南美白对虾、中华绒鳌蟹为样品,建立了喹烯酮(QCT)和喹赛多(CYA)及其主要代谢物脱二氧喹烯酮(BDQCT)、3-甲基喹啉-2-羧酸(MQCA)、脱二氧喹赛多(BDCYA)和喹啉-2-羧酸(QCA)多残留的高效液相色谱-串联质谱(HPLC-MS/MS)确证检测方法。组织样品经乙腈-乙酸乙酯(1∶1)、盐酸溶液分步提取,Oasis MAX固相萃取柱净化,以甲醇、乙腈和0.1%甲酸溶液为流动相,经Waters XBridge C18色谱柱分离后,采用HPLC-MS/MS仪进行测定。采取正离子选择反应监测模式检测,外标法定量。结果表明,喹烯酮和喹赛多及其主要代谢物的响应值与其质量浓度在2~500μg/L范围内线性关系良好。在加标浓度为5~50μg/kg范围内,6种待测物的平均回收率为76.3%~94.2%,相对标准偏差为4.2%~11.7%。方法的检出限为0.5~1.6μg/kg,定量下限为2.0~5.0μg/kg。该方法适用于水产品中QCT和CYA及其主要代谢物残留的确证检测和同时定量分析。     

Oligo(rU)_(15)对SDS/DEAB混合胶束向囊泡转化的诱导作用

囊泡是由表面活性剂分子分散在水中形成的具有密闭双分子层结构的球形或者椭球形的分子有序组合体,在生物学、材料学、化学和医药学等领域具有极为重要和广泛的应用~([1-4]).     

高斯叠代法研究相控阵非线性声场

相控阵在聚焦超声治疗应用中不可避免地受到非线性影响,提出了采用高斯叠代法计算相控阵的非线性声场。在该方法中,利用预设焦点参数并应用伪逆矩阵算法得到阵元的激励参数;然后将阵元近似拟合成一组高斯声束的叠加,通过高斯声束叠代计算非线性声场。数值计算中以64阵元一维相控阵为研究对象;线性条件下,高斯叠代法结果与菲涅耳积分结果的误差低于0.5%,验证了该方法的可行性;单焦点及双焦点模式的相控阵非线性声场结果表明非线性效应能提高焦点聚焦性能,并且非线性效应与激励声压及激励频率成正比。     

固体粗糙界面与超声的非线性相互作用研究

本文提出了一种随机弹性接触界面与超声的非线性相互作用理论. 首先建立了描述随机弹性接触界面的模型, 然后分别研究了界面间应力-应变关系在线性简化模型、指数模型、高斯模型下与超声的非线性相互作用. 数值仿真和实验研究结果均表明高斯模型更适合描述固体接触界面. 本文在介观结构上解释了固体界面与超声的相互作用, 对工业超声无损检测裂缝、缺陷及损伤有指导意义. 关键词： 超声无损检测 固体粗糙界面 非线性效应     

Two-Dimensional Lorentz Force Image Reconstruction for Magnetoacoustic Tomography with Magnetic Induction

Magnetoacoustic tomography with magnetic induction has shown potential applications in imaging the electrical impedance for biological tissues. We present a novel methodology for the inverse problem solution of the 2-D Lorentz force distribution reconstruction based on the acoustic straight line propagation theory. The magnetic induction and acoustic generation as well as acoustic detection are theoretically provided as explicit formulae and also validated by the numerical simulations for a multilayered cylindrical phantom model. The reconstructed 2-D Lorentz force distribution reveals not only the conductivity configuration in terms of shape and size but also the amplitude value of the Lorentz force in the examined layer. This study provides a basis for further study of conductivity distribution reconstruction of MAT-MI in medical imaging.     

载流子输运和寄生参数对隧道再生双有源区垂直腔面发射激光器调制特性的影响

建立了一种适用于多量子阱和多有源区的多层速率方程模型. 通过小信号分析,得到了光子密度、载流子俘获、逃逸和隧穿时间等关键参数对单有源区和隧道再生双有源区垂直腔面发射激光器频率响应特性的影响,并分析了在相同驱动电流下隧道再生双有源区器件调制带宽大于单有源区器件的原因. 进一步研究了隧道再生双有源区内腔接触氧化限制型垂直腔面发射激光器的寄生电参数及其寄生电路,对其频率响应进行了模拟分析. 关键词： 垂直腔面发射激光器 速率方程 调制特性 隧道再生