Directed Evolution of Human Cu,Zn-SOD Under Artificial Oxidant Pressures

IntroductionSuperoxide dismutases play an important rolein organisms′ defense against highly reactiveoxygen species by removing the superoxideanions[1— 3 ] . According to their metal cofactor,three differentclasses of superoxide dismutases canbe distinguished:Cu,Zn- SOD,Fe- SOD and Mn-SOD. These three SODs are different in thephylogenetic distribution pattern,prokaryotescontain Mn- SOD,Fe- SOD or both,and Cu,Zn-SODs in the cytosol and peroxisomes of eukaryotesand homologous prote…     

Highly Sensitive Spectrofluorimetric Determination of Trace Amounts of Indium(Ⅲ) with Salicylaldehyde Salicyloylhydrazone

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｒｅｃｅｎｔｙｅａｒｓ ,ａｒｏｙｌｈｙｄｒａｚｏｎｅｓｗｈｉｃｈｃｏｎｔａｉｎｇｒｏｕｐ—ＣＯＮＨＮ ＣＨ—ｈａｖｅｂｅｅｎｔｅｓｔｅｄａｓｆｌｕｏｒｉ ｍｅｔｒｉｃｒｅａｇｅｎｔｓｆｏｒｔｈｅｄｅｔｅｒｍｉｎａｔｉｏｎｏｆａｌｕｍｉｎｕｍ ,ｇａｌｌｉｕｍ ,ｓｃａｎｄｉｕｍ ,ｚｉｎｃ ,ｃｏｐｐｅｒａｎｄｏｔｈｅｒｍｅｔａｌｉｏｎｓ[17] .Ｔｈｅｒｅａｃｔｉｏｎｏｆａｍｅｔａｌｉｏｎｗｉｔｈａｃｈｅｌａｔｉｎｇａｇｅｎｔｐｒｏｄｕｃｅｓａｒｉｇｉｄｍｏｌｅｃｕｌｅｗｉｔｈａ…     

基于FPGA的血液分析仪驱动电路设计

提出了一种基于 FPGA 的血液分析仪驱动电路设计,以及一种基于频率测量的步进电机故障检测方法.其驱动电路采用模块化和自底向上的设计方法,实现对4个步进电机和24路电磁阀的并行驱动和实时故障检测,并可通过串行通讯与主控机进行数据交换.     

聚合物-富勒烯太阳能电池器件物理研究进展

近期共轭聚合物-富勒烯太阳能电池的器件效率已突破10%并接近商业应用的标准,在科研和产业领域引起了广泛关注. 伴随器件效率的提升,对有机太阳能电池器件物理过程的认识也在不断深入. 本文就近年来聚合物太阳能电池的代表性工作进行综述,着重介绍提高器件效率的新方法,涵盖三相本体异质结、反向器件、等离激元共振效应和叠层器件等热点技术;并就器件工作的物理过程进行探讨,介绍热激子分离理论、非整数次电荷复合等新观点. 通过材料设计、器件表征优化和理论计算等方法对聚合物太阳能电池进行的综合研究将有力推进这一新兴领域的发展和产业化.     

γ-聚谷氨酸水凝胶的性质、制备及其应用

系统介绍了γ-聚谷氨酸水凝胶的制备方法及其生物可降解性、高吸水性及保湿性、pH敏感性、生物相容性和可修饰性等性能,同时综合介绍了其在组织工程、药物控释和创面修复等方面的应用,结合本研究组工作对其未来的发展进行了展望。     

Preparation of Zirconia Based Packing Material and Its Evaluation

Silica-based packing materials have two serious drawbacks: lackness of pH stability and severe peak tailing in separation of basic solutes1,2. Recently, zirconia has been put much attention because of its high mechanical and chemical stability. Zirconia is completely stable from pH 1 to 14, even at temperature of 100(C3. The porous zirconia microspheres used as column packings can be synthesized by means of polymerization-induced colloid aggregation (PICA) method4,5 or a sol-gel process6. M…     

EFFECTS OF ALKALI AND RARE EATTH METAL OXIDES ON THE THERMAL STABILITY AND THE CARBON DEPOSITION OVER A NiO/Al_2O_3 CATALYST

采用固定床流动反应装置、ＣＯ吸附、ＴＧ、ＴＰＯ、ＸＰＳ和ＸＲＤ等手段考察了ＮｉＯ／Ａｌ２Ｏ３和ＬｉＮｉＬａＯ／Ａｌ２Ｏ３催化剂上的甲烷部分氧化反应。实验结果表明，ＬｉＮｉＬａＯ／Ａｌ２Ｏ３对甲烷部分氧化反应具有较高的反应活性。锂和镧的添加不仅改善了活性组分镍的分散度，而且提高了ＮｉＯ／Ａｌ２Ｏ３的抗积碳能力和热稳定性     

Fourth-Order Splitting Methods for Time-Dependant Differential Equations

This study was suggested by previous work on the simulation of evolution equations with scale-dependent processes,e.g.,wave-propagation or heat-transfer,that are modeled by wave equations or heat equations.Here,we study both parabolic and hyperbolic equations.We focus on ADI (alternating direction implicit) methods and LOD (locally one-dimensional) methods,which are standard splitting methods of lower order,e.g.second-order.Our aim is to develop higher-order ADI methods,which are performed by Richardson extrapolation,Crank-Nicolson methods and higher-order LOD methods,based on locally higher-order methods.We discuss the new theoretical results of the stability and consistency of the ADI methods.The main idea is to apply a higher- order time discretization and combine it with the ADI methods.We also discuss the dis- cretization and splitting methods for first-order and second-order evolution equations. The stability analysis is given for the ADI method for first-order time derivatives and for the LOD (locally one-dimensional) methods for second-order time derivatives.The higher-order methods are unconditionally stable.Some numerical experiments verify our results.     

Synthesis and Crystal Structure of α-( N-Protected a mino)β- lactam Derivative of 1 ,5-Benzothiazepine

１　ＩＮＴＲＯＤＵＣＴＩＯＮＲｅｃｅｎｔｌｙ,ａｎｕｍｂｅｒｏｆｄｅｒｉｖａｔｉｖｅｓｏｆｂｅｎｚｏｔｈｉａｚｅｐｉｎｅｈａｖｅｂｅｅｎｐｒｅｐａｒｅｄａｎｄｓｔｕｄｉｅｄｆｏｒｔｈｅｉｒｐｈａｒｍａｃｏｌｏｇｉｃａｌａｃｔｉｖｉｔｉｅｓ〔１５〕．Ｉｎｏｕｒｐｒｅｖｉｏｕｓｗｏｒｋ,ｗｅｈａｖｅｉｎｃｏｒｐｏｒａｔｅｄｔｈｅβｌａｃｔａｍｒｉｎｇｉｎｔｏ１,５ｂｅｎｚｏｔｈｉａｚｅｐｉｎｅｂｙｒｅａｃｔｉｏｎｏｆ１,５ｂｅｎｚｏｔｈｉａｚｅｐｉｎｅｗｉｔｈｓｏｍｅａｃｙｌｃｈｌｏｒｉｄ…     

Synthesis and Crystal Structure of Dicesium trans Dicarbonatotetraaquomagnesium, Cs_2[Mg(CO_3)_2(H_2O)_4]

ＩｎｔｒｏｄｕｃｔｉｏｎＰｒｅｖｉｏｕｓｌｙ,ｗｅｒｅｐｏｒｔｅｄｔｈｅｃｒｙｓｔａｌｓｔｒｕｃｔｕｒｅｏｆＫ２［Ｎｉ（ＣＯ３）２（Ｈ２Ｏ）４］［１］,ｗｈｉｃｈｃｒｙｓｔａｌｌｉｚｅｄｉｎｔｈｅｂａｙｌｉｓｓｉｔｅｔｙｐｅｓｔｒｕｃｔｕｒｅａｎｄｗａｓｆｏｕｎｄｔｏｂｅｉｓｏｓｔｒｕｃｔｕｒａｌｗｉｔｈＫ２［Ｃｏ（ＣＯ３）２（Ｈ２Ｏ）４］［２］ａｎｄＫ２Ｍｇ（ＣＯ３）２·４Ｈ２Ｏ［３］．Ｉｎｏｒｄｅｒｔｏｓｙｓｔｅｍａｔｉｃａｌｌｙｉｎｖｅｓｔｉｇａｔｅｔｈｅｏｃｃｕｒｒｅｎｃｅｏｆｔｈｅｃｏ…