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31.
32.
Naoyuki Masuda Osamu Yamamoto Masahiro Fujii Tetsuro Ohgami Ayako Moritomo Toru Kontani 《合成通讯》2013,43(17):2305-2316
Various N‐3‐alkylated thiazolidenesulfonamide derivatives were efficiently prepared by the direct endo‐selective alkylation of thiazolylsulfonamides. The effects of different bases and solvents were investigated, and the NaH–THF combination was found to be the most effective at conferring high yields and endo‐selectivity. 相似文献
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Masahiro Terashima Takuya Miyayama Tetsuro Shirao Hin Wai Mo Yasuhiro Hatae Hiroshi Fujimoto Katsumi Watanabe 《Surface and interface analysis : SIA》2020,52(12):948-952
Low-energy inverse photoelectron spectroscopy (LEIPS) and ultraviolet photoelectron spectroscopy (UPS) incorporated into the multitechnique XPS system were used to probe the ionization potential and the electron affinity of organic materials, respectively. By utilizing gas cluster ion beam (GCIB), in situ analyses and depth profiling of LEIPS and UPS were also demonstrated. The band structures of the 10-nm-thick buckminsterfullerene (C60) thin film on Au (100 nm)/indium tin oxide (100 nm)/glass substrate were successfully evaluated in depth direction. 相似文献
35.
Yukiko Yasuoka Yuichiro Izumi Takashi Fukuyama Haruki Omiya Truyen D. Pham Hideki Inoue Tomomi Oshima Taiga Yamazaki Takayuki Uematsu Noritada Kobayashi Yoshitaka Shimada Yasushi Nagaba Tetsuro Yamashita Masashi Mukoyama Yuichi Sato Susan M. Wall Jeff M. Sands Noriko Takahashi Katsumasa Kawahara Hiroshi Nonoguchi 《Molecules (Basel, Switzerland)》2022,27(3)
Anemia is a major complication of chronic renal failure. To treat this anemia, prolylhydroxylase domain enzyme (PHD) inhibitors as well as erythropoiesis-stimulating agents (ESAs) have been used. Although PHD inhibitors rapidly stimulate erythropoietin (Epo) production, the precise sites of Epo production following the administration of these drugs have not been identified. We developed a novel method for the detection of the Epo protein that employs deglycosylation-coupled Western blotting. With protein deglycosylation, tissue Epo contents can be quantified over an extremely wide range. Using this method, we examined the effects of the PHD inhibitor, Roxadustat (ROX), and severe hypoxia on Epo production in various tissues in rats. We observed that ROX increased Epo mRNA expression in both the kidneys and liver. However, Epo protein was detected in the kidneys but not in the liver. Epo protein was also detected in the salivary glands, spleen, epididymis and ovaries. However, both PHD inhibitors (ROX) and severe hypoxia increased the Epo protein abundance only in the kidneys. These data show that, while Epo is produced in many tissues, PHD inhibitors as well as severe hypoxia regulate Epo production only in the kidneys. 相似文献
36.
The Cu, As and Se contents of Au-containing CuAsSe glasses significantly affected both the resistivity in the memory state and the time required to reach the memory state, whereas the Au content affects only the latter. The main crystalline species formed in these glasses was a CuAsSe compound, and its formation was enhanced by the addition of Au. The role of Au in the memory effect was discussed on the basis of crystallization behavior of glasses. 相似文献
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Tetsuro Yamamoto 《Numerische Mathematik》1980,34(2):189-199
Summary On the basis of an existence theorem for solutions of nonlinear systems, a method is given for finding rigorous error bounds for computed eigenvalues and eigenvectors of real matrices. It does not require the usual assumption that the true eigenvectors span the whole space. Further, a priori error estimates for eigenpairs corrected by an iterative method are given. Finally the results are illustrated with numerical examples.Dedicated to Professor Yoshikazu Nakai on his sixtieth birthday 相似文献
40.
Hiroyuki Inouye Yoshio Takeda Shinichi Uesato Kenichi Uobe Toshiro Hashimoto Tetsuro Shingu 《Tetrahedron letters》1980,21(11):1059-1062
Hydrangenoside A, isolated along with its three congeners from Hydrangea macrophylla, was proved to have a novel type of structure which is thought to be biosynthesized through an aldol-type condensation of secologanin with a unit formed by the shikimate-malonate route followed by decarboxylation. 相似文献