Application of ion-exchange cartridge clean-up in food analysis IV. Confirmatory assay of benzylpenicillin, phenoxymethylpenicillin, oxacillin, cloxacillin, nafcillin and dicloxacillin, in bovine tissues by liquid chromatography-electrospray ionization tandem mass spectrometry

A multiresidue analytical method was developed for the confirmation of benzylpenicillin (PCG), phenoxymethylpenicillin (PCV), oxacillin (MPIPC), cloxacillin (MCIPC), nafcillin (NFPC) and dicloxacillin (MDIPC) in bovine tissues using electrospray ionization liquid chromatography-tandem mass spectrometry (LC-ESI-MS-MS) with a product ion scan mode. All penicillins gave [M-H]-, [M-H-CO2]- and [M-H-141]- as the product ion, when [M-H]- was selected as the precursor ion. Combination of an ion-exchange cartridge clean-up and the LC-ESI-MS-MS method can reliably identify all of these penicillins fortified at a concentration of 0.05 mg/kg in bovine tissues, including liver, kidney and muscle. The limits of confirmation satisfy the maximum residue limits for each of the penicillins established by the World Health Organization, US Food and Drug Administration, European Union and Japan.     

Survey of residual tetracyclines in kidneys of diseased animals in Aichi Prefecture, Japan (1985-1997)

A survey was conducted to determine the incidence of tetracycline antibiotic (TCAs) residues in the kidneys of slaughtered animals that did not pass inspection for human consumption by the Japanese Food Sanitation Law and the Meat Inspection Law at the slaughterhouses in Aichi Prefecture, Japan, from April 1985 to March 1998. The kidneys were analyzed by the AOAC Official Method 995.09. Among 424 animals (147 cattle and 277 pigs), 131 (30.9%) were contaminated with TCAs, including 69 (16.3%) with chlortetracycline (CTC), 61 (14.4%) with oxytetracycline (OTC), 3 (0.7%) with tetracycline (TC), and 1 (0.2%) with doxycycline (DC). One sample (cattle kidney) was contaminated with both OTC and DC. The frequencies of OTC and TC residues were significantly higher (p < 0.05) in cattle than in pigs, whereas, the frequency of CTC was significantly higher (p < 0.01) in pigs. Pig kidney samples collected in 1991-1997 had significantly higher incidences of TCAs and CTC (p < 0.01) residues than those in 1985-1986.     

NAD(P)+-NAD(P)H model. 38. Reduction of aldehyde by 1,4-dihydroquinolin derivative

Benzaldehyde are reduced to benzyl alcohol by a model compound of NAD(P)H almost quantitatively. Reductions of some other aldehydes are also mentioned.     

Global solvability for abstract semilinear evolution equations

The Cauchy problem for the abstract semilinear evolution equation u^′(t) = Au (t) + B (u (t)) + C (u (t)) is discussed in a general Banach space X. Here A is the so‐called Hille‐Yosida operator in X, B is a differentiable operator from D (A) into X, and C is a locally Lipschitz continuous operator from D (A) into itself. A vectorvalued functional defined only on X is used and appropriate conditions on the nonlinear operators B and C are imposed so that a vector‐valued functional defined on the domain of the operator A may be constructed in order to specify the growth of a global solution. The advantage of our formulation lies in the fact that it is possible to obtain a global solution by checking some energy inequalities concerning only low order derivatives (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)     

Fundamental groups of the complements of certain plane non-tame torus sextics

The moduli space of torus sextics with the configuration of singularities {A₂+A₅+2E₆} has two connected components. We compute the fundamental groups π₁(CP²−C) for sextics C in both components and study their differences.     

An ergodic theorem for asymptotically nonexpansive mappings in the intermediate sense

This paper is concerned with an ergodic theorem for asymptotically nonexpansive mappings in the intermediate sense in Banach spaces.

     

Estimation of surface charges on dielectric materials for high power rf windows

The surface discharges observed at rf windows and vacuum circuit breakers (VCBs) are one of the difficulties faced when developing high-power rf windows or compact VCBs. The surface discharge is considered to take place due to the release of the surface charges. Despite the importance of the surface charging/discharging, these phenomena have not been well evaluated. In this paper, the surface charges are estimated using the multipulse method, where electron beam irradiates a sample up to the saturation condition of surface charges. The amount of surface charges on alumina and TiN coated alumina are compared and the charging mechanism is discussed.