A 4-Methylumbelliferone-based Fluorescent Probe for Sodium New Houttuyfonate

A new fluorogenic probe for sodium new houttuyfonate (SNH) was proposed. 4‐Methylumbelliferyl‐2,4‐dinitrobenzenesulfonate (4‐MUDNBS) was a nonfluorescent compound and was synthesized via the one‐step reaction of 4‐methylumbelliferone (4‐MU) with 2,4‐dinitrobenzenesulfonyl chloride. In basic media, SNH was decomposed to produce sodium sulfite, which then reacted with 4‐MUDNBS to yield highly fluorescent 4‐MU, hence leading to the fluorescence increase of the reaction solution. A linear correlation existed between the emission intensity and the concentration of SNH within the range from 0.5 to 15 μg·mL⁻¹ with a detection limit of 0.15 μg· mL⁻¹ (3δ). The effect of substituents on the benzenesulfonyl moiety of the probe is discussed, and the presence of electronegative groups is favorable for the proposed cleavage reaction.     

Electrogenerated chemiluminescence of poly[(2,2′-bipyridyl)(4-(2-pyrrol-1-ylethyl)-4′-methyl-2,2′-bipyridyl)2]ruthenium (II) film

Elelctrogenerated chemiluminescence (ECL) of electropolymerized films based on [(2,2′-bipyridyl)(4-(2-pyrrol-1-ylethyl)-4′-methyl-2,2′-bipyridyl)₂]ruthenium (II) was firstly investigated in both organic and aqueous solution. The ECL behaviors have been explained by two typical mechanisms, namely, redox-cycling type and oxidative-reduction type. For the former, no co-reactant was required and for the latter, tripropylamine (TPA) and (NH₄)₂C₂O₄ were selected as co-reactants in the organic and aqueous system, respectively.     

Photopromoted carbonylation of 1-bromo-6-chlorohexane under ambient conditions

Photopromoted carbonylation of 1-bromo-6-chlorohexane with CO catalyzed by CuBr2 and CdI2 has been carried out under ambient conditions. The results indicate that the carbonylation proceeds with the major product of chloroester ClCH2（CH2）5COOCH3 under catalysis of CuBr2. Furthermore, the activity of the carbonylation can be improved by addition of basic additives （NaOAc, Na3PO4 or （n-C4H9）3N）. Among these additives, （n-C4H9）3N is the most efficient in terms of the yield of ClCH2（CH2）5COOCH3. However, the methoxycarbonyl substituting chlorine product of BrCH2（CH2）5COOCH3 is not obtained in the presence of CdI2. This is quite different from the carbonylation of monochloroalkane.     

Schiff碱N,N’-双水杨醛缩-1,6-己二胺的光致变色光谱研究

用稳态和时间相关荧光光谱、紫外 -可见吸收光谱和傅立叶变换红外光谱等方法研究了 Schiff碱N ,N -双水杨醛缩 -1 ,6-己二胺 ( BSH)的光致变色行为 .确定了光致变色的产物为双质子转移的酮式结构 .     

A MEMS micromirror driven by electrostatic force

A microelectromechanical systems (MEMS) micromirror is demonstrated in this paper. The micromirror is actuated by an electrostatic force and can achieve a large out of plane stroke by eliminating the electrostatic pull-in effect. The micromirror consists of a mirror of 400 μm by 400 μm in the center, a spring and three fixed bottom electrodes each side. Design principles and the analytical model are both developed, and they are verified by finite element analysis (FEA). The resonant frequency for the piston movement of the designed micromirror is about 2.5 kHz by FEA simulation. The micromirror prototype has been fabricated by a surface micromachining process and it is successfully tested using a microsystem analyzer. An out of plane stroke of 1.65 μm is observed at 100 V and it agrees well with the predicted result from analytical model.     

Synthesis,Crystal Structure and Magnetic Behaviour of {[Co(dimb)2(H2O)2]·(NO3)2·(H2O)2}n

The title complex {[Co(dimb)₂(H₂O)₂]·(NO₃)₂·(H₂O)₂}_n ( 1 ) (dimb = 1,3‐di(imidazol‐1‐ylmethyl)‐5‐methylbenzene) has been hydrothermally synthesized by the reaction of dimb with Co(NO₃)₂·6H₂O in aqueous solution. The cobalt(II) atoms are linked by bridging dimb ligands to form 2D corrugated and wavy networks containing Co₄(dimb)₄ macrocyclic motifs. Two neighboring independent layers interlinked each other in a parallel fashion to construct three‐dimensional structure by O–H···O, N–H···O and C–H···O hydrogen bonds. Magnetic measurement shows the weak antiferromagnetic interaction with a one‐dimensional chain model in the range of 5–300 K, with J of –0.68 cm⁻¹.     

Synthesis and Properties of D-Thymidylyl (3'→5')L-Thymidine (D/L-TpT)

Inrecentyearsmuchefforthasbeenspenttodevelopoligonucleotideanalogsashighlyselectivepharmaceuticalagentstoblockexpressionofdisease-associatedproteins'-'.andtheseefT'ortshaveresultedilltheapprovaloffomiversensodium(vitravene',"),thefirstantisensedrug,byFDAinAugust1998fortreatmentofAIDSpatientswithcytomegalovirus(CMV)-inducedretinitis6.However,thegreatpotentialofantisenseoligonucleotidesasantiviralandanticanceragentsiscompromisedbytheirnucleasesusceptibilityandlowcellmembranepermeability.L-D…