Two New Triterpene Saponins from the Seed Residue of Hippophae rhamnoides L.

Two new triterpene saponins, named hippophosides E and F ( 1 and 2 , resp.), together with two known compounds, were isolated from the seed residue of Hippophae rhamnoides L. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D‐ and 2D‐NMR and HR‐MS experiments, and by comparison with literature data.     

Exploiting the 1,2,3‐Triazole Moiety to Generate Carbazole Molecular Architectures through Click Approach

Reaction of 3,6‐dichlorocarbazole with propargyl bromide in the presence of a basic medium gave an N‐propargylated carbazole. The latter compound was converted into molecular architectures containing 1,2,3‐triazole moiety through Cu(I)‐catalyzed 1,3‐cycloaddition reaction with different azides. Similarly, 2‐azidomethyl benzothiazole was cliched with N‐Boc‐protected N´‐propargyl glutamate to give the biomolecule 2‐triazolylmethyl product.     

A Convenient Synthesis of Pyridophenanthroline Derivatives under Catalyst Free Conditions

A three‐component reaction between an aromatic aldehyde, quinolin‐6‐amine or quinolin‐5‐amine, and tert‐butyl 2,4‐dioxopiperidine‐1‐carboxylate in reflux EtOH gave pyrido phenanthroline derivatives in high yields under catalyst free conditions. The rare C‐H…F hydrogen bond is found in the crystal structure of 6h .