工科基础物理实验课程教学改革与实践

提出了模块化教学体系的新思路及具体实施方案。在教学上将传统内容与现代高新技术相互结合;教学方法上将程序式与多元式相结合,注重了基本技能、实验总结能力和创新精神的培养。总结了试点以来取得的教学经验和体会,并对不足之处进行了分析。     

从(-)-莽草酸出发合成(3R,5R)-3,4,5-三苯甲酰氧基环己酮

报道了一种合成手性中间体(3R,5R)-3,4,5-三羟基环己酮的新方法。首次以(-)-莽草酸为起始原料,经苯甲酰化、双键氢化、选择性还原甲酯、羟基碘代、碘代烃消除、双键双羟化、片哪醇断裂等步骤,以44.9%的总收率合成了(3R,5R)-3,4,5-三苯甲酰氧基环己酮,所有化合物的结构经¹H NMR、 ¹³C NMR、 IR及MS等确证。      

熊去氧胆酸的合成研究进展

熊去氧胆酸（UDCA）是一种多功能亲水性胆汁酸,是治疗胆汁淤积性肝病的重要药物之一。以胆酸（CA）、猪去氧胆酸（HDCA）、鹅去氧胆酸（CDCA）等为起始原料的化学合成法已广泛应用于工业化生产;生物合成主要以CDCA或CA为底物,经氧化还原脱氢酶异构化得到UDCA,工艺绿色、环保、高效,是该类药物合成研究的主要方向。本文对UDCA的化学、生物合成方法进行了综述,分析并展望了现有技术的优势及发展方向。     

新型热声谐振机构的理论分析和实验验证

谐振管作为热声发动机的重要组成部分,其长度占整个系统轴向长度的大部分。本文提出了一种利用液体和弹性膜组成谐振系统的方法,并使用这种谐振系统取代谐振管,使系统轴向尺寸减少为原来的1/5。文中利用线性热声理论对该谐振系统的谐振频率进行了计算,并对不同阻尼系数对系统的耗散做出了分析。实验结果表明,在利用驻波热声发动机驱动的情况下,谐振系统自激起振,谐振频率为360 Hz,实际谐振频率与计算值误差在5%以内。     

Controlling Entanglement Dynamics by Choosing Appropriate Ratio between Cavity-Fiber Coupling and Atom-Cavity Coupling

The entanglement characteristics including the so-called sudden death effect between two identical twolevel atoms trapped in two separate cavities connected by an optical fiber are studied. The results show that the time evolution of entanglement is sensitive not only to the degree of entanglement of the initial state but also to the ratio between cavity-fiber coupling （v） and atom-cavity coupling （g）. This means that the entanglement dynamics can be controlled by choosing specific v and ft.     

Design study of an FEL oscillator with a waveguide

We present a design study of a free electron laser （FEL） oscillator for high power THz source experiments on the basis of the Shanghai femtosecond accelerator device. A circular groove guide is used as a new interaction structure. Plane metal meshes are used as upstream and downstream mirrors of the resonator. The general design parameters are presented. We analyzed the spontaneous emission and stimulated emission in the oscillator using these parameters.     

Design of a PXR experiment based on the NCEL

Parametric X-ray Radiation （PXR） can be used as a novel, quasi-monochromatic energy-tunable and high-yield X-ray source. It is produced at the Bragg angle by a relativistic electron beam passing through the periodic structure of crystal materials. This article concerns the PXR experiment using low energy electrons （10 MeV） from NCEL （Novel Compact Electron-Linac）. The difficulty of the experiment is to distinguish the PXR photons form the background. The design of the experiment relies mainly on the yield of PXR, the Bremsstrahlung background of the X-rays and the capability of the detector.     

High Power THz Undulator Radiation from Linear Accelerator

A 30-MeV femto-second electron linac is built at the Shanghai Institute of Applied Physics, which can produce high power, coherent THz undulator radiation. We report the experimental facility and measurement of the power, frequency spectrum. First experiments show the averaged power at THz to be about 20mW.     

Numerical Investigation on Inviscid Instability of Streaky Structures in Incompressible Boundary Layer Flow

Numerical investigation is made on the effect of streaky structures in transition by inviscid linear disturbance equation with temporal mode. Several disturbances with different streamwise wave numbers were induced, and the evolutions with time step were received. It suggests that the exponential growth and periodic variation of the waves are in existence. As the streamwise wave number increases, the disturbance growth rate begins by increasing, reaches a maximum at around α=0.4 with a disturbance frequency of 0.2186 ＋ 0.001457i, and then decreases. Furthermore, the eigenfunctions of pressure disturbance are plotted.