全文获取类型
收费全文 | 184篇 |
免费 | 15篇 |
专业分类
化学 | 145篇 |
晶体学 | 3篇 |
力学 | 9篇 |
数学 | 12篇 |
物理学 | 30篇 |
出版年
2022年 | 1篇 |
2021年 | 5篇 |
2020年 | 3篇 |
2019年 | 13篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 6篇 |
2015年 | 12篇 |
2014年 | 9篇 |
2013年 | 16篇 |
2012年 | 9篇 |
2011年 | 20篇 |
2010年 | 15篇 |
2009年 | 7篇 |
2008年 | 14篇 |
2007年 | 11篇 |
2006年 | 7篇 |
2005年 | 8篇 |
2004年 | 9篇 |
2003年 | 4篇 |
2002年 | 9篇 |
2001年 | 3篇 |
2000年 | 5篇 |
1999年 | 1篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1991年 | 1篇 |
排序方式: 共有199条查询结果,搜索用时 15 毫秒
121.
Beyhan Erdem Saliha Büşra Avşar Sezer Erdem Nalan Tekin 《Journal of Dispersion Science and Technology》2013,34(9):1227-1235
AbstractFe3O4@SiO2@NH2 nanocomposite was prepared for highly effective adsorption of two anionic dyes one of which is triarylmethane dye (light green, LG) and the other is azo dye (brilliant yellow, BY). The characterization results demonstrated that superparamagnetic Fe3O4 nanoparticles were covered with silica and functionalized with amino groups successfully without losing magnetic character. The effects of adsorbent dosage, contact time, pH, temperature, and dye molecular structure on the adsorption were investigated. Acidic pH was better for both LG and BY, on the other hand, alkaline pH was favorable to some extent for LG in comparison with BY due to the contribution of stacking effect in addition to electrostatic attraction. Kinetic data demonstrated that the driving force for adsorption process could be explained by pseudo-second order mechanism in both systems. The equilibrium data were more compatible with Langmuir isotherm than those of Freundlich isotherm and the maximum adsorption capacities of Fe3O4@SiO2@NH2 calculated from Langmuir isotherm model for LG and BY at 30?°C and natural pH of the solution were 40.2 and 35.5?mg g?1. Thermodynamic calculations related to temperature dependence demonstrated that the adsorption process was spontaneous and exothermic. 相似文献
122.
Yumak T Kuralay F Muti M Sinag A Erdem A Abaci S 《Colloids and surfaces. B, Biointerfaces》2011,82(2):397-403
The interaction of PLGA-chitosan Nanoplexes with ocular mucosa was investigated ex vivo and in vivo to assess their potential as ocular delivery system. Fluorescent Rhodamine Nanoplexes (Rd-Nanoplexes) were prepared by ionotropic gelation method. The size and morphology of Nanoplexes was investigated by TEM, SEM and PCS. The corneal retention, uptake and penetration of Nanoplexes were analyzed by spectrofluorimetry and confocal microscopy. Corneas from Rd-Nanoplexes-treated rabbits were evaluated for the in vivo uptake and ocular tolerance. The Nanoplexes prepared were round with a mean diameter of 115.6±17nm and the encapsulation efficiency of Rd was 59.4±2.5%. Data from ex vivo and in vivo studies showed that the amounts of Rd in the cornea were significantly higher for Nanoplexes than for a control Rd solution, these amounts being fairly constant for up to 24h. Confocal microscopy of the corneas revealed paracellular and transcellular uptake of the Nanoplexes. The uptake mechanism postulated was adsorptive-mediated endocytosis and opening of the tight junctions between epithelial cells. No alteration was microscopically observed after ocular surface exposure to Nanoplexes. Taken together, these data demonstrate that Nanoplexes are potentially useful as ocular drug carriers. 相似文献
123.
Coupling amperometry and total internal reflection fluorescence microscopy at ITO surfaces for monitoring exocytosis of single vesicles 总被引:1,自引:0,他引:1
124.
In the present study a chitosan/ionic liquid modified pencil graphite electrode (CHIT‐IL‐PGEs) was developed for the first time for enhanced electrochemical monitoring of nucleic acid, and the interaction of the anticancer drug Mitomycin C (MC) and calf thymus double stranded DNA (dsDNA) by measuring the oxidation signals of MC and guanine in the same voltammetric scale. Differential pulse voltammetry, cyclic voltammetry and electrochemical impedance spectroscopy techniques were used to evaluate the performance of the CHIT‐IL based biosensor on electrochemical monitoring of DNA, and drug‐DNA interaction. The experimental parameters, IL, dsDNA and MC concentration and the interaction time were then optimized. 相似文献
125.
Four new trinuclear Fe(III) and Cr(III) complexes involving tetradenta Schiff bases N,N′-bis(salicylidene)ethylenediamine-(salenH2) or bis(salicylidene)-o-phenylenediamine-(saloph H2) with 2,4,6-tris(4-nitrophenylimino-4′-formylphenoxy)-1,3,5-triazine (TNPI-TRIPOD) have been synthesized and characterized by means of elemental analysis carrying out 1H-NMR., IR spectroscopy, thermal analyses and magnetic susceptibility measurements. The complexes can also be characterized as high-spin distorted octahedral Fe(III) and Cr(III) bridged by nitro. The nitro play a role as bridges for weak anti-ferromagnetic intramolecular exchange. 相似文献
126.
127.
Electrochemical Detection of Activated Protein C Using an Aptasensor Based on PAMAM Dendrimer Modified Pencil Graphite Electrodes
下载免费PDF全文
![点击此处可从《Electroanalysis》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Electrochemical aptasensing of APC was carried out using PAMAM dendrimer modified pencil graphite electrodes (PGEs) for the first time herein. Poly(amidoamine) dendrimer having 16 succinamic acid surface groups (generation 2, G2‐PS) modified PGEs were developed, and then were utilized for APC monitoring using differential pulse voltammetry, electrochemical impedance spectroscopy and cyclic voltammetry. The selectivity of single‐use aptasensor was tested against to other proteins; BSA and THR as well as to the affinity of APC binding to different DNA aptamer, or oligonucleotide. Voltammetric APC detection was also explored in a diluted fetal bovine serum resulting with a detection limit DL as 1.5 µg/mL. 相似文献
128.
Hasan Kırmızıbekmez Hilal Bardakcı Milena Masullo Özge Kamburoğlu Gonca Eryılmaz Galip Akaydın Erdem Yeşilada Sonia Piacente 《Helvetica chimica acta》2014,97(11):1571-1576
A new flavonol glycoside, quercetin 3‐O‐[6′′′‐O‐3,5‐dihydroxycinnamoyl‐β‐glucopyranosyl‐(1→2)]‐β‐galactopyranoside (named lilacifloroside; 1 ) and a new iridoid 2 (named asperulogenin), were isolated from the aerial parts of Asperula lilaciflora in addition to eight known secondary metabolites, i.e., quercetin, kaempferol, quercetin 3‐O‐β‐glucopyranosyl‐(1→2)‐β‐galactopyranoside, quercetin 3‐O‐β‐glucopyranosyl‐(1→2)‐arabinopyranoside, asperuloside, deacetylasperulosidic acid, asperulosidic acid methyl ester, and chlorogenic acid. The structures were elucidated on the basis of extensive 1D‐ and 2D‐NMR experiments as well as MS data. Compound 1 contains the rare 3,5‐dihydroxycinnamoyl moiety in its structure. This work constitutes the first phytochemical study of the title plant. 相似文献
129.
130.