降解PET聚酯瓶实验条件的研究——综合研究型实验设计

为了从废PET聚酯瓶中回收对苯二甲酸(TPA),分别对比研究了酸性水解法、肼解法和醇碱联合法降解PET聚酯瓶的反应收率及环境友好性、经济性等.通过正交实验,探索了醇碱联合解聚法的最佳反应条件.采用红外光谱对回收的对苯二甲酸进行了表征,结合量子化学计算对振动光谱和分子间氢键进行了研究.     

Preparation and Structure of a New Coagulation Factor XI Catalytic Domain for Drug Discovery

Human blood coagulation factor XI (FXI) is a key enzyme in the amplification phase of blood coagulation cascade,and is recognized as an important target for anti-coagulant deve-lopment in recent years.We designed a new mutant form of FXIa catalytic domain rhFXI 370～607 (N73Q-N113Q-C123S),and report here the facile preparation,protein crystallization,and crystal structure of this protein.We highlight a few unique structural features of FXIa after comparison with the trypsin family serine proteases at sequence and structural levels.This work provides a foundation to develop new small molecular FXIa inhibitors with increased potency and specificity.     

ENDPOINT ESTIMATES FOR THE COMMUTATOR OF PSEUDO-DIFFERENTIAL OPERATORS

It is well known that the commutator Tb of the Calder′on-Zygmund singular integral operator is bounded on Lp(Rn) for 1 p +∞if and only if b∈BMO [1]. On the other hand, the commutator Tb is bounded from H1(Rn) into L1(Rn) only if the function b is a constant [2]. In this article, we will discuss the boundedness of commutator of certain pseudo-differential operators on Hardy spaces H1. Let Tσbe the operators that its symbol is S01,δwith 0≤δ 1, if b∈LMO∞, then, the commutator [b, Tσ] is bounded from H1(Rn) into L1(Rn) and from L∞(Rn) into BMO(Rn); If [b, Tσ] is bounded from H1(Rn) into L1(Rn) or L∞(Rn) into BMO(Rn), then, b∈LMO_(loc).     

Maltose-binding Protein Improving the Crystallizability of C2 Domain of Human Coagulation Factor V

Human coagulation Factor V（FV）, together with Factor Xa, assembles to prothrombinase complex on activated cell surface, which converts prothrombin into thrombin, leading to fibrin deposition. The C2 domain of FV is believed to be a primary anchor for the assembly of pro- thrombinase on the cell surface, and was proposed as a target to intervene with pathological thrombotic events. We report here the crystal structure of the C2 domain of FV fused to maltose-binding protein（MBP）. The fusion tag of MBP is critical to generate the crystal for this study. There is no strong interaction between MBP and FVC2. The overall structure of FVC2 is similar to the previous FVC2 structures, suggesting the MBP fusion does not perturb the molecular structure of FVC2. This crystal form of FVC2 can be used for future study of molecular interaction between FVC2 and its inhibitors.     

基于单像素成像的微小位移测量方法

激光散斑位移测量法是一种重要的现代光学位移测量方法,由于受到图像传感器元件感光性能限制,难以在强干扰光条件下获得有效散斑场信息,进而无法获取位移场数据,因此,基于单像素成像技术,本文提出一种新的激光散斑位移测量方法:对散斑信息进行图案编码调制,并使用单像素探测器采集调制后的光强信息;利用Walsh-Hadamard Transformation(WHT)成像算法对散斑场图像进行重建;最后结合自相关算法确定物体的位移场信息。分别利用商业相机和单像素成像技术对散射介质的单轴微小位移进行测量,结果表明基于单像素成像技术的激光散斑位移测量技术可以获得较好的测量结果。相比于传统测量方法,基于单像素成像技术的激光散斑位移测量方法在复杂环境中具有一定的优势,可实现强光干扰下的位移场测量。     

Novel temperature modeling and compensation method for bias of ring laser gyroscope based on least-squares support vector machine

Bias of ring-laser-gyroscope (RLG) changes with temperature in a nonlinear way. This is an important restraining factor for improving the accuracy of RLG. Considering the limitations of least-squares regression and neural network, we propose a new method of temperature compensation of RLG bias building function regression model using least-squares support vector machine (LS-SVM). Static and dynamic temperature experiments of RLG bias are carried out to validate the effectiveness of the proposed method. Moreover, the traditional least-squares regression method is compared with the LS-SVM-based method. The results show the maximum error of RLG bias drops by almost two orders of magnitude after static temperature compensation, while bias stability of RLG improves by one order of magnitude after dynamic temperature compensation. Thus, the proposed method reduces the influence of temperature variation on the bias of the RLG effectively and improves the accuracy of the gyro scope considerably.     

混合溶剂中多组分电解质溶液热力学性质的研究——Ⅲ.HCl-NaCl-i-PrOH-H_2O体系(5—45℃)

在恒定溶液总离子强度I=1.00mol·kg~(-1), 改变异丙醇在混合溶剂中的摩尔分数x=0.025、0.075和0.100条件下,测定了无液接界电池(A)和电池(B)的电动势。 Pt,H_2(1.013×10~5Pa)|HCl(m),i-PrOH(x),H_2O(1-x)|AgCl-Ag (A) Pt,H_2(1.013×10~5Pa)|HCl(m_A),NaCl(m_B),i-PrOH(x),H_2O(1-x)|AgCl-Ag(B) 根据电池(A)的电动势,确定混合溶剂中Ag-AgCl电极的标准电极电势,讨论了HCl的迁移性质。利用电池(B)的电动势,确定HCl活度系数γ_A。结果表明,在恒定I为1.00mol·kg~(-1)时,HCl的活度系数仍然服从Harned规则。在恒定溶液组成时,lgγ_A对热力学温度的倒数1/T作图,具有良好直线关系。进一步讨论了混合物中HCl的相对偏摩尔焓和HCl的溶剂化数及介质效应。     

对称矩阵分解因子的直接换元修正法

§1.引言 考虑非线性方程组 F(x)=0, (1)其中F:Ω?R~n→R~n使F′(x)对称.本文给出求解(1)的一种分解修正法,这种方法始于Jacobian F′(x)的初始对称三角分解,然后利用换元技巧直接修正上三角分解因子,进而前代与回代求迭代点.本文分析了分解修正法的运算量,证明了这个算法不用重新启动仍具有局部超线性收敛性和大范围收敛性.此外,这个算法自然保持分解因子的稀疏传递性和修正矩阵的对称传递性,特别当Jacobian正定时,还具有正定传递性.由此本文完成了[1]和[2]无法完成的工作.本算法特别适于大规模带状方程组和最优化问题,数值例子也表明了这一点.     

素环上导子的线性组合

In this paper we discuss the linear combination of derivations in prime rings which was initiated by Niu Fengwen.Our aim is to improve Niu‘s result.For the proof of the main theorem we generalize a result of Bresar and obtain a lemma that is of independent interest.